scholarly journals Limfoma Non-Hodgkin Primer Vertebra Torakalis dengan Kompresi Progresif Medula Spinalis

2016 ◽  
Vol 1 (3) ◽  
pp. 193-203
Author(s):  
Nurhuda Hendra Setyawan ◽  
Lina Choridah ◽  
Yana Supriatna
Keyword(s):  
Spinal Cord ◽  
Hodgkin Lymphoma ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Spinal Tumors ◽  
Clinical Consequence ◽  
Histopathological Analysis ◽  
Systemic Involvement ◽  
Non Hodgkin Lymphoma ◽  
Rare Occasion

Primary vertebral of non-hodgkin lymphoma presented without systemic involvement is extremely rare. Bone is only 1% found as the primary origin of lymphoma. Primary vertebral location is only 1.7% of all primary bone lymphomas. The tumor grows insidiously and may reach considerable size and clinical consequence prior to diagnosis. When the tumor compresses or infltrates the spinal cord, the symptoms may be rapidly progressive, and proper surgical treatment may be needed to preserve function and to maintain the quality of life.We reported a 70-year-old man presented with progressive lower extremities weakness and numbness, back pain, and incontinentia alvi for the last six months. Magnetic resonance imaging demonstrated T1 and T2 hypointense mass that destructed 10th thoracic vertebral body, right laminae, and right pedicle. The mass compressed spinal canal and spinal cord. Histopathological analysis from open biopsy revealed a non-hodgkin lymphoma of the 10th thoracic vertebra.Isolated primary bony lymphoma of the spine is a very rare occasion. In our case, the initial complaints may be the result of progressive spinal cord compression. Thus, radiologists have to be familiar with imaging fndings of various spinal tumors that can cause spinal cord compression.

Co-Incidence of Guillain-Barré Syndrome and Spinal Cord Compression in Non-Hodgkin Lymphoma

1994 ◽  
Vol 25 (01) ◽  
pp. 36-38 ◽  
Author(s):  
K. Gücüyener ◽  
S. Keskil ◽  
M. Baykaner ◽  
E. Bilir ◽  
A. Oğuz ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Hodgkin Lymphoma ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Guillain Barre Syndrome ◽  
Non Hodgkin Lymphoma ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

A multicenter study of 66 patients with spinal cord compression at diagnosis of B-cell non-Hodgkin lymphoma.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 8560-8560
Author(s):  
Isabelle Fleury ◽  
Sandy Amorim ◽  
Nicolas Mounier ◽  
Bertrand Coiffier ◽  
Jehan Dupuis ◽  
...  
Keyword(s):  
Spinal Cord ◽  
B Cell ◽  
Hodgkin Lymphoma ◽  
Spinal Cord Compression ◽  
Multicenter Study ◽  
Cord Compression ◽  
Non Hodgkin Lymphoma

Clinical outcomes of treatment for spinal cord compression due to primary non-Hodgkin lymphoma

2013 ◽  
Vol 13 (6) ◽  
pp. 641-650 ◽  
Author(s):  
Yu Tang ◽  
Xinghai Yang ◽  
Jianru Xiao ◽  
Ke Liu ◽  
Wangjun Yan ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Hodgkin Lymphoma ◽  
Clinical Outcomes ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Non Hodgkin Lymphoma

scholarly journals Initial presentation of Hodgkin’s Lymphoma as Extradural Spinal Cord Compression: A case report

2020 ◽  
Vol 11 (2) ◽  
pp. 101-103
Author(s):  
Rishav Mukherjee ◽  
Sampurna Chowdhury
Keyword(s):  
Spinal Cord ◽  
Hodgkin Lymphoma ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Acute Onset ◽  
Initial Presentation ◽  
Classical Hodgkin Lymphoma ◽  
Night Sweats ◽  
History Of ◽  
Mediastinal Widening

A 23 year old female presented with acute onset paraparesis. She denied any history of fever, weight loss or drenching night sweats. Neither did she have any obvious lymphadenopathy on general examination. Chest Xray was however suggestive of mediastinal widening and her MRI spine showed metastases with superior mediastinal SOL. Biopsy of this SOL ultimately revealed classical Hodgkin lymphoma. Thus this was a very unusual initial presentation of Hodgkin lymphoma presenting as Epidural Spinal Cord Compression. Hasenclever IPS score was 2. Patient was treated with radiotherapy followed by ABVD chemotherapy and achieved remission in 3months.

Decompression surgery and intraoperative radiation therapy (IORT) for metastatic spinal tumors

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 20515-20515
Author(s):  
K. Karasawa ◽  
N. Hanyu ◽  
T. Chang ◽  
G. Kuga ◽  
D. Yoshida ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Response Rate ◽  
Posterior Instrumentation ◽  
Cord Compression ◽  
Intraoperative Radiation Therapy ◽  
Spinal Tumors ◽  
Decompression Surgery ◽  
Intraoperative Radiation ◽  
Neurological Response

20515 Background: Metastatic spinal tumors often cause spinal cord compression and jeopardize the quality of life of the patients much. To decrease the local symptomatic recurrence rate, we have been adding IORT to decompression surgery. Methods: For those patients whose life expectancy was more than 6 months were eligible for this treatment. Posterior decompression by laminectomy of the involved vertebrae was performed. Following decompression, the patient was irradiated the lesions intraoperatively with electrons generated from Microtron by shielding the spinal cord with lead plate. The central aspects of the vertebrae were irradiated by scattered electrons detouring from the edge of the lead shield up to 40% of the administered dose. Following IORT, posterior instrumentation was performed. External beam radiotherapy might be added pre- and/or postoperatively when considered necessary. Results: 108 patients were treated between 1992–2005. There were 58 males and 50 females. Age ranged from 26 to 85 with a median of 62.5. By primary sites, 26 breast, 24 kidney, 18 colorectum, 17 lung 12 prostate and 11 thyroid cases were included. Irradiated spines were cervical in 6, thoracic in 76, and lumbar/sacral in 27. Overall median follow-up period was 12.7months. Median IORT dose was 20Gy (range 15–26Gy) and median electron energy was 16MeV (range 11–22MeV). There were 37 cases with preoperative RT and 41 cases with postoperative RT. Overall median survival time was 14.5months (breast 15.3, kidney 22.6, colorectum 5.7, lung 6.2, prostate 31.6, thyroid 60.6months). Neurological response rate was 73.1%. Ambulatory rates were 87.0% for success and 80.6% for rescue by Klimo's definition(2005). There were only 8 symptomatic relapses (7%). As for major complications, only one myelopathy has been observed. Conclusions: Decompression surgery and IORT for metastatic spinal tumors with impending spinal cord compression was a promising treatment modality with excellent local control and neurological response rate and with minimal toxicity especially for those patients with long-term prognosis. No significant financial relationships to disclose.

The surgical management of metastatic spinal tumors based on an Epidural Spinal Cord Compression (ESCC) scale

2015 ◽  
Vol 15 (8) ◽  
pp. 1738-1743 ◽  
Author(s):  
Nasir A. Quraishi ◽  
George Arealis ◽  
Khalid M.I. Salem ◽  
Sanjay Purushothamdas ◽  
Kimberly L. Edwards ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Surgical Management ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Spinal Tumors

scholarly journals Spinal cord compression as tumor onset: an unusual case report of Hodgkin lymphoma in a teenager

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Giulia Salomone ◽  
Milena La Spina ◽  
Giuseppe Belfiore ◽  
Gregoria Bertuna ◽  
Laura Cannavò ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Back Pain ◽  
Hodgkin Lymphoma ◽  
Spinal Cord Compression ◽  
Diagnostic Delay ◽  
Specific Treatment ◽  
Immunohistochemical Analysis ◽  
Cord Compression ◽  
Neurological Function ◽  
Neurological Abnormalities

Abstract Background Spinal cord compression (SCC) is an uncommon, severe complication of Hodgkin lymphoma (HL), occurring in 0.2% of cases at the onset and in 6% during disease progression. We present a teenager with SCC with clinical onset of HL; her pre-existing neurological abnormalities covered the presence of an epidural mass, which could have misled us. Case presentation A 13-year-old girl presented with a three-month history of lower back pain and degrading ability to walk. She suffered from a chronic gait disorder due to her preterm birth. A magnetic resonance imaging of the spine revealed an epidural mass causing collapse of twelfth thoracic vertebra and thus compression and displacement of the spinal cord. Histological examination with immunohistochemical analysis of the epidural mass demonstrated a classic-type Hodgkin lymphoma. Early pathology-specific treatment allowed to avoid urgent surgery, achieve survival and restore of neurological function. Conclusions Children and adolescents with back pain and neurological abnormalities should be prioritized to avoid diagnostic delay resulting in potential loss of neurological function. SCC requires a prompt radiological assessment and an expert multidisciplinary management.

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