scholarly journals A Diastereodivergent and Enantioselective Approach to syn- and anti-Diamines: Development of 2-Azatrienes for Cu-Catalyzed Reductive Couplings with Imines that Furnish Allylic Amines

2021 ◽  
Author(s):  
Pengfei Zhou ◽  
Xinxin Shao ◽  
Steven Malcolmson
Keyword(s):  
Allylic Amines ◽  
Reductive Couplings

scholarly journals A Diastereodivergent and Enantioselective Approach to syn- and anti-Diamines: Development of 2-Azatrienes for Cu-Catalyzed Reductive Couplings with Imines that Furnish Allylic Amines

2021 ◽  
Author(s):  
Pengfei Zhou ◽  
Xinxin Shao ◽  
Steven Malcolmson
Keyword(s):  
Enantioselective Synthesis ◽  
Allylic Amines ◽  
Reductive Couplings

We introduce a new reagent class, 2-azatrienes, as a platform for catalytic enantioselective synthesis of allylic amines. Herein, we demonstrate their promise by diasteredivergent and enantioselective synthesis of <i>syn</i>- and <i>anti</i>-1,2-diamines by Cu-bis(phosphine)-catalyzed reductive couplings with imines. With Ph-BPE, <i>anti</i>-diamines are obtained, and with the rarely utilized t-Bu-BDPP, <i>syn</i>-diamines are generated.<br>

scholarly journals A Diastereodivergent and Enantioselective Approach to syn- and anti-Diamines: Development of 2-Azatrienes for Cu-Catalyzed Reductive Couplings with Imines that Furnish Allylic Amines

2021 ◽  
Author(s):  
Pengfei Zhou ◽  
Xinxin Shao ◽  
Steven Malcolmson
Keyword(s):  
Enantioselective Synthesis ◽  
Allylic Amines ◽  
Reductive Couplings

We introduce a new reagent class, 2-azatrienes, as a platform for catalytic enantioselective synthesis of allylic amines. Herein, we demonstrate their promise by diasteredivergent and enantioselective synthesis of <i>syn</i>- and <i>anti</i>-1,2-diamines by Cu-bis(phosphine)-catalyzed reductive couplings with imines. With Ph-BPE, <i>anti</i>-diamines are obtained, and with the rarely utilized t-Bu-BDPP, <i>syn</i>-diamines are generated.<br>

Palladium(II)-catalysed oxidation of allylic amines with molecular oxygen

1994 ◽  
pp. 357 ◽  
Author(s):  
Rolf A. T. M. van Benthem ◽  
Henk Hiemstra ◽  
Jasper J. Michels ◽  
W. Nico Speckamp
Keyword(s):  
Molecular Oxygen ◽  
Allylic Amines ◽  
Catalysed Oxidation

Allylic selenides in organic synthesis: new methods for the synthesis of allylic amines

1986 ◽  
Vol 51 (26) ◽  
pp. 5243-5252 ◽  
Author(s):  
Regan G. Shea ◽  
Jeffrey N. Fitzner ◽  
John E. Fankhauser ◽  
Andreas Spaltenstein ◽  
Philip A. Carpino ◽  
...  
Keyword(s):  
Organic Synthesis ◽  
Allylic Amines ◽  
New Methods

scholarly journals Exploring the full catalytic cycle of rhodium(i)–BINAP-catalysed isomerisation of allylic amines: a graph theory approach for path optimisation

2017 ◽  
Vol 8 (6) ◽  
pp. 4475-4488 ◽  
Author(s):  
Takayoshi Yoshimura ◽  
Satoshi Maeda ◽  
Tetsuya Taketsugu ◽  
Masaya Sawamura ◽  
Keiji Morokuma ◽  
...  
Keyword(s):  
Graph Theory ◽  
Reaction Mechanism ◽  
Catalytic Cycle ◽  
Theory Approach ◽  
Allylic Amines ◽  
Reaction Route ◽  
Reaction Method ◽  
Mapping Strategy ◽  
Global Reaction ◽  
Induced Reaction

The reaction mechanism of the cationic rhodium(i)–BINAP complex catalysed isomerisation of allylic amines was explored using the artificial force induced reaction method with the global reaction route mapping strategy.

Highly Regioselective and Diastereoselective Epoxidation of Allylic Amines with Oxone.

ChemInform ◽  
2005 ◽  
Vol 36 (48) ◽  
Author(s):  
Varinder K. Aggarwal ◽  
Guang Yu Fang
Keyword(s):  
Allylic Amines
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