scholarly journals Bioengineered exosomes as delivery vehicles of small interfering RNA for stem cell engineering and in vivo delivery

2016 ◽  
Vol 4 ◽  
Author(s):  
Jin Yoonhee ◽  
Lee Jung Seung ◽  
Park Hyuni-Ji ◽  
Min Sungjin ◽  
Cho Seung-Woo
Keyword(s):  
Stem Cell ◽  
Small Interfering Rna ◽  
Cell Engineering ◽  
Stem Cell Engineering ◽  
Delivery Vehicles ◽  
Interfering Rna ◽  
In Vivo Delivery

Delivery Vehicles for Small Interfering RNA In Vivo

2008 ◽  
Vol 19 (2) ◽  
pp. 125-132 ◽  
Author(s):  
Antonin R. de Fougerolles
Keyword(s):  
Small Interfering Rna ◽  
Delivery Vehicles ◽  
Interfering Rna

Preclinical Imaging of siRNA Delivery

2016 ◽  
Vol 69 (10) ◽  
pp. 1073 ◽  
Author(s):  
Nicholas Fletcher ◽  
Aditya Ardana ◽  
Kristofer J. Thurecht
Keyword(s):  
Molecular Imaging ◽  
Clinical Application ◽  
Small Interfering Rna ◽  
Sirna Delivery ◽  
Preclinical Imaging ◽  
Current State ◽  
Delivery Vehicles ◽  
Significant Uptake ◽  
Interfering Rna

Small interfering RNA (siRNA) is emerging as a class of therapeutic with extremely high potential, particularly in the field of oncology. Despite this growing interest, further understanding of how siRNA behaves in vivo is still required before significant uptake into clinical application. To this end, many molecular imaging modalities have been utilised to gain a better understanding of the biodistribution and pharmacokinetics of administered siRNA and delivery vehicles. This highlight aims to provide an overview of the current state of the field for preclinical imaging of siRNA delivery.

In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers

2010 ◽  
Vol 24 (9) ◽  
pp. 3122-3134 ◽  
Author(s):  
Paula Ofek ◽  
Wiebke Fischer ◽  
Marcelo Calderón ◽  
Rainer Haag ◽  
Ronit Satchi‐Fainaro
Keyword(s):  
Small Interfering Rna ◽  
Interfering Rna ◽  
In Vivo Delivery
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