scholarly journals Damage to Broca’s area OR the anterior temporal lobe is implicated in stroke-induced agrammatic comprehension: it depends on the task

2015 ◽  
Vol 6 ◽  
Author(s):  
Rogalsky Corianne ◽  
LaCroix Arianna ◽  
Chen Kuan-Hua ◽  
Anderson Steven ◽  
Damasio Hanna ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Broca’S Area ◽  
Broca's Area ◽  
Anterior Temporal Lobe

The temporal cortex

2020 ◽  
pp. 253-259
Author(s):  
Edmund T. Rolls
Keyword(s):  
Temporal Lobe ◽  
Language Production ◽  
Inferior Frontal Gyrus ◽  
Temporal Cortex ◽  
Visual Object ◽  
Broca’S Area ◽  
Semantic Representations ◽  
Broca's Area ◽  
Anterior Temporal Lobe ◽  
Face Expression

The inferior and middle temporal gyri are involved visual object recognition, with the more dorsal areas involved in face expression, gesture, and motion representation that is useful in social behaviour. The superior temporal cortex is involved in auditory processing. The anterior temporal lobe is involved in semantic representations, for example information about objects, people, and places. Network mechanisms involved in semantic representations are described. The output of this system reaches the inferior frontal gyrus, which on the left is Broca’s area, involved in language production. The concept that the semantics for language are computed in the anterior temporal lobe, and communicates with Broca’s area for speech production, is introduced.

scholarly journals The neurobiology of agrammatic sentence comprehension: a lesion study

2017 ◽  
Author(s):  
Corianne Rogalsky ◽  
Arianna N. LaCroix ◽  
Kuan-Hua Chen ◽  
Steven W. Anderson ◽  
Hanna Damasio ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Sentence Processing ◽  
Word Order ◽  
Sentence Comprehension ◽  
Functional Neuroimaging ◽  
Matching Task ◽  
Broca’S Area ◽  
Broca's Area ◽  
Cognitive Demands ◽  
Lesion Symptom Mapping

AbstractBroca’s area has long been implicated in sentence comprehension. Damage to this region is thought to be the central source of “agrammatic comprehension” in which performance is substantially worse (and near chance) on sentences with noncanonical word orders compared to canonical word order sentences (in English). This claim is supported by functional neuroimaging studies demonstrating greater activation in Broca’s area for noncanonical versus canonical sentences. However, functional neuroimaging studies also have frequently implicated the anterior temporal lobe (ATL) in sentence processing more broadly, and recent lesion-symptom mapping studies have implicated the ATL and mid temporal regions in agrammatic comprehension. The present study investigates these seemingly conflicting findings in 66 left hemisphere patients with chronic focal cerebral damage. Patients completed two sentence comprehension measures, sentence-picture matching and plausibility judgments. Patients with damage including Broca’s area (but excluding the temporal lobe; n=11) on average did not exhibit the expected agrammatic comprehension pattern, e.g. their performance was > 80% on noncanonical sentences in the sentence-picture matching task. Patients with ATL damage (n=18) also did not exhibit an agrammatic comprehension pattern. Across our entire patient sample, the lesions of patients with agrammatic comprehension patterns in either task had maximal overlap in posterior superior temporal and inferior parietal regions. Using voxel-based lesion symptom mapping (VLSM), we find that lower performances on canonical and noncanonical sentences in each task are both associated with damage to a large left superior temporal-inferior parietal network including portions of the ATL, but not Broca’s area. Notably however, response bias in plausibility judgments was significantly associated with damage to inferior frontal cortex, including gray and white matter in Broca’s area, suggesting that the contribution of Broca’s area to sentence comprehension may be related to task-related cognitive demands.

scholarly journals The Neurobiology of Agrammatic Sentence Comprehension: A Lesion Study

2018 ◽  
Vol 30 (2) ◽  
pp. 234-255 ◽  
Author(s):  
Corianne Rogalsky ◽  
Arianna N. LaCroix ◽  
Kuan-Hua Chen ◽  
Steven W. Anderson ◽  
Hanna Damasio ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Sentence Processing ◽  
Word Order ◽  
Sentence Comprehension ◽  
Functional Neuroimaging ◽  
Matching Task ◽  
Broca’S Area ◽  
Broca's Area ◽  
Cognitive Demands ◽  
Lesion Symptom Mapping

Broca's area has long been implicated in sentence comprehension. Damage to this region is thought to be the central source of “agrammatic comprehension” in which performance is substantially worse (and near chance) on sentences with noncanonical word orders compared with canonical word order sentences (in English). This claim is supported by functional neuroimaging studies demonstrating greater activation in Broca's area for noncanonical versus canonical sentences. However, functional neuroimaging studies also have frequently implicated the anterior temporal lobe (ATL) in sentence processing more broadly, and recent lesion–symptom mapping studies have implicated the ATL and mid temporal regions in agrammatic comprehension. This study investigates these seemingly conflicting findings in 66 left-hemisphere patients with chronic focal cerebral damage. Patients completed two sentence comprehension measures, sentence–picture matching and plausibility judgments. Patients with damage including Broca's area (but excluding the temporal lobe; n = 11) on average did not exhibit the expected agrammatic comprehension pattern—for example, their performance was >80% on noncanonical sentences in the sentence–picture matching task. Patients with ATL damage ( n = 18) also did not exhibit an agrammatic comprehension pattern. Across our entire patient sample, the lesions of patients with agrammatic comprehension patterns in either task had maximal overlap in posterior superior temporal and inferior parietal regions. Using voxel-based lesion–symptom mapping, we find that lower performances on canonical and noncanonical sentences in each task are both associated with damage to a large left superior temporal–inferior parietal network including portions of the ATL, but not Broca's area. Notably, however, response bias in plausibility judgments was significantly associated with damage to inferior frontal cortex, including gray and white matter in Broca's area, suggesting that the contribution of Broca's area to sentence comprehension may be related to task-related cognitive demands.

scholarly journals Syntax-sensitive regions of Broca’s area and the posterior temporal lobe are differentially recruited by production and perception

2020 ◽  
Author(s):  
William Matchin ◽  
Emily Wood
Keyword(s):  
Temporal Lobe ◽  
Regions Of Interest ◽  
Syntactic Processing ◽  
Broca’S Area ◽  
Broca's Area ◽  
Fmri Study ◽  
Lesion Symptom Mapping

AbstractNeuroimaging studies of syntactic processing typically result in similar activation profiles in Broca’s area and the posterior temporal lobe (PTL). However, substantial functional dissociations between these regions have been demonstrated with respect to lesion-symptom mapping in aphasia. To account for this, Matchin & Hickok (2020) proposed that both regions play a role in syntactic processing, broadly construed, but attribute distinct functions to these regions with respect to production and comprehension. Here we report an fMRI study designed to test this hypothesis by contrasting the subvocal articulation and comprehension of structured jabberwocky phrases (syntactic), sequences of real words (lexical), and sequences of pseudowords (phonological). We defined two sets of language-selective regions of interest (ROIs) in individual subjects for Broca’s area and the PTL using the contrasts [syntactic > lexical] and [syntactic > phonological]. We found robust significant interactions of comprehension and production between these two regions at the syntactic level, for both sets of language-selective ROIs. This suggests a core difference in the function of these regions: language-selective subregions of Broca’s area play a role in syntax driven by the demands of production, whereas language-selective subregions of the PTL play a role in syntax driven by the demands of comprehension.

The „narrow faculty“ and Broca's area

2008 ◽  
Vol 35 (S 01) ◽  
Author(s):  
M Musso ◽  
A Schneider ◽  
C Büchel ◽  
C Weiller
Keyword(s):  
Broca’S Area ◽  
Broca's Area

scholarly journals Cerebral trauma-induced dyschromatopsia in the left hemifield: case presentation

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yoko Mase ◽  
Yoshitsugu Matsui ◽  
Eriko Uchiyama ◽  
Hisashi Matsubara ◽  
Masahiko Sugimoto ◽  
...  
Keyword(s):  
Visual Field ◽  
Color Vision ◽  
Temporal Lobe ◽  
Fusiform Gyrus ◽  
Ganglion Cell Complex ◽  
Automated Perimetry ◽  
Subjective Symptoms ◽  
Anterior Temporal Lobe ◽  
Case Presentation ◽  
Cerebral Trauma

Abstract Background Acquired color anomalies caused by cerebral trauma are classified as either achromatopsias or dyschromatopsias (Zeki, Brain 113:1721–1777, 1990). The three main brain regions stimulated by color are V1, the lingual gyrus, which was designated as human V4 (hV4), and the fusiform gyrus, designated as V4α. (Zeki, Brain 113:1721–1777, 1990). An acquired cerebral color anomaly is often accompanied by visual field loss (hemi- and quadrantanopia), facial agnosia, prosopagnosia, visual agnosia, and anosognosia depending on the underlying pathology (Bartels and Zeki, Eur J Neurosci 12:172–193, 2000), (Meadows, Brain 97:615–632, 1974), (Pearman et al., Ann Neurol 5:253–261, 1979). The purpose of this study was to determine the characteristics of a patient who developed dyschromatopsia following a traumatic injury to her brain. Case presentation The patient was a 24-year-old woman who had a contusion to her right anterior temporal lobe. After the injury, she noticed color distortion and that blue objects appeared green in the left half of the visual field. Although conventional color vision tests did not detect any color vision abnormalities, short wavelength automated perimetry (SWAP) showed a decrease in sensitivity consistent with a left hemi-dyschromatopsia. Magnetic resonance imaging (MRI) detected abnormalities in the right fusiform gyrus, a part of the anterior temporal lobe. At follow-up 14 months later, subjective symptoms had disappeared, but the SWAP abnormalities persisted and a thinning of the sectorial ganglion cell complex (GCC) was detected. Conclusion The results indicate that although the subjective symptoms resolved early, a reduced sensitivity of SWAP remained and the optical coherence tomography (OCT) showed GCC thinning. We conclude that local abnormalities in the anterior section of fusiform gyrus can cause mild cerebral dyschromatopsia without other symptoms. These findings indicate that it is important to listen to the symptoms of the patient and perform appropriate tests including the SWAP and OCT at the early stage to objectively prove the presence of acquired cerebral color anomaly.

Sign in / Sign up

Export Citation Format

Share Document