scholarly journals Syncope as the Initial Manifestation of Advanced Nasopharyngeal Carcinoma: A Case Report

2022 ◽  
Vol 8 ◽  
Author(s):  
Si-Cheng Zhang ◽  
Mao-Qing Lin ◽  
Li-Wei Zhang ◽  
Xue-Qin Lin ◽  
Man-Qing Luo ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Carotid Sinus ◽  
The Elderly ◽  
Initial Symptom ◽  
Initial Manifestation ◽  
Carotid Sinus Syndrome ◽  
Positron Emission ◽  
Nasopharyngeal Biopsy ◽  
History Of

Carotid sinus syndrome is a principal cause of syncope in the elderly. Syncope, associated with carotid sinus syndrome which is secondary to metastasis of advanced nasopharyngeal carcinoma, rarely occurs. The current study reported a 66-year-old woman, who presented with a history of frequent and recurrent syncope as the initial symptom, and was eventually diagnosed with advanced nasopharyngeal carcinoma. The positron emission tomography scan demonstrated a diagnosis of advanced nasopharyngeal carcinoma with involvement in carotid sheath space, and nasopharyngeal biopsy revealed non-keratinized nasopharyngeal carcinoma. After diagnosis and treatment, the patient had no recurrence of syncope. In summary, our case study suggests that great importance should be attached to potential intrinsic causes of syncope especially in the case of nasopharyngeal carcinoma, as it is an insidious malignancy which needs to be precisely identified.

Headache as the Initial Manifestation of Acute Aortic Dissection Type A

Cephalalgia ◽  
1998 ◽  
Vol 18 (8) ◽  
pp. 583-584 ◽  
Author(s):  
C Stöllberger ◽  
J Finsterer ◽  
C Fousek ◽  
FR Waldenberger ◽  
H Haumer ◽  
...  
Keyword(s):  
Chest Pain ◽  
Aortic Dissection ◽  
Initial Symptom ◽  
Thoracic Pain ◽  
Initial Manifestation ◽  
Initial Symptoms ◽  
Rare Differential Diagnosis ◽  
History Of ◽  
Diastolic Murmur ◽  
Base Of The Skull

The most common initial symptom of aortic dissection is chest pain. Other initial symptoms include pain in the neck, throat, abdomen and lower back, syncope, paresis, and dyspnoea. Headache as the initial symptom of aortic dissection has not been described previously. A 61-year-old woman with a history of migraine and arterial hypertension developed continuous bifrontal headache. Two hours later, right-sided thoracic pain and a diastolic murmur were suggestive of aortic dissection that was confirmed by echocardiography and subsequent surgery. The dissection commenced in the ascending aorta and involved all cervical arteries until the base of the skull. Headache as the initial manifestation of aortic dissection was assumed due to either vessel distension or pericarotid plexus ischemia. Aortic dissection has to be considered as a rare differential diagnosis of frontal headache, especially in patients who develop aortic regurgitation or chest pain for the first time.

scholarly journals Behavioral variant of frontotemporal dementia or frontal variant of Alzheimer's disease? A case study

2019 ◽  
Vol 13 (3) ◽  
pp. 356-360
Author(s):  
Leonardo Cruz de Souza ◽  
Luciano Inácio Mariano ◽  
Renata Freire de Moraes ◽  
Paulo Caramelli
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Frontotemporal Dementia ◽  
Csf Biomarkers ◽  
Positron Emission ◽  
Personality Changes ◽  
Clinical Presentations ◽  
History Of ◽  
Executive Deficits

ABSTRACT Alzheimer's disease (AD) has heterogeneous clinical presentations. Amnestic progressive disorder leading to dementia is the most typical, but non-amnestic presentations are also recognized. Here we report a case of frontal variant of AD. A right-handed woman, aged 68 years, was referred for progressive behavioral disorders and personality changes. She had a corroborated history of dietary changes, hyperorality, impulsivity, affective indifference and apathy, with functional impairment. Cognitive assessment yielded severe executive deficits. Positron emission tomography with fluorodeoxyglucose showed marked hypometabolism in frontotemporal regions, with relative preservation of parietal regions. CSF AD biomarkers showed low Aβ42, high Tau and high P-Tau. The patient fulfilled criteria for probable behavioral variant frontotemporal dementia. However, considering the AD pathophysiological signature on CSF biomarkers, a diagnosis of frontal variant of AD was established. In the perspective of disease-modifying therapies, it is important to identify atypical Alzheimer presentations, as these patients may be candidates for specific treatments.

The Clinical Characterstics of Vasodepressor and Cardioinhibitory Carotid Sinus Syndrome in the Elderly

1993 ◽  
Vol 22 (suppl 3) ◽  
pp. P17-P17
Author(s):  
S. J. McIntosh ◽  
J. Lawson ◽  
R. A. Kenny
Keyword(s):  
Carotid Sinus ◽  
The Elderly ◽  
Carotid Sinus Syndrome

The carotid sinus syndrome: A frequently overlooked cause of syncope in the elderly

1986 ◽  
Vol 4 (4) ◽  
pp. 376-383 ◽  
Author(s):  
Jon Schellack ◽  
J. Timothy Fulenwider ◽  
Richard A. Olson ◽  
Robert B. Smith ◽  
Kamal Mansour
Keyword(s):  
Carotid Sinus ◽  
The Elderly ◽  
Carotid Sinus Syndrome

Borderline Personality Disorder in the Elderly: A Case Study

1986 ◽  
Vol 31 (9) ◽  
pp. 859-860 ◽  
Author(s):  
Daniel J. Siegel ◽  
Gary W. Small
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Natural History ◽  
The Elderly ◽  
Borderline Personality ◽  
History Of

Little is known about the natural history of Borderline Personality Disorder (BPD) among the aged. A case is presented of a 69-year-old woman who met six of the eight DSM-III criteria for the diagnosis of BPD, The case suggests that features of BPD persist throughout life and may worsen with the stresses associated with aging.

scholarly journals The carotid sinus syndrome: A frequently overlooked cause of syncope in the elderly

1986 ◽  
Vol 4 (4) ◽  
pp. 376-383 ◽  
Author(s):  
Jon Schellack ◽  
J.Timothy Fulenwider ◽  
Richard A. Olson ◽  
Robert B. Smith ◽  
Kamal Mansour
Keyword(s):  
Carotid Sinus ◽  
The Elderly ◽  
Carotid Sinus Syndrome
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