scholarly journals Neodymium-140 DOTA-LM3: Evaluation of an In Vivo Generator for PET with a Non-Internalizing Vector

2017 ◽  
Vol 4 ◽  
Author(s):  
Gregory W. Severin ◽  
Lotte K. Kristensen ◽  
Carsten H. Nielsen ◽  
Jesper Fonslet ◽  
Andreas I. Jensen ◽  
...  
Keyword(s):  
In Vivo Generator

scholarly journals Efforts to Control the Errant Products of a Targeted In vivo Generator

2005 ◽  
Vol 65 (11) ◽  
pp. 4888-4895 ◽  
Author(s):  
Jaspreet Singh Jaggi ◽  
Barry J. Kappel ◽  
Michael R. McDevitt ◽  
George Sgouros ◽  
Carlos D. Flombaum ◽  
...  
Keyword(s):  
In Vivo Generator

[166Dy]Dysporium/[166Ho]Holmium In Vivo generator

1995 ◽  
Vol 46 (8) ◽  
pp. 759-764 ◽  
Author(s):  
Suzanne V. Smith ◽  
Nadine Di Bartolo ◽  
Saed Mirzadeh ◽  
Richard M. Lambrecht ◽  
F.F. Knapp ◽  
...  
Keyword(s):  
In Vivo Generator

The in vivo generator for radioimmunotherapy

1989 ◽  
Vol 26 (1-12) ◽  
pp. 498-500 ◽  
Author(s):  
L.F. Mausner ◽  
R.F. Straub ◽  
S.C. Srivastava
Keyword(s):  
In Vivo Generator

Radiolabeled TPP with 166Dy/166Ho in vivo generator as a novel therapeutic agent

2020 ◽  
Vol 326 (1) ◽  
pp. 813-821
Author(s):  
Nafise Salek ◽  
Sara Vosoughi ◽  
Ali Bahrami Samani ◽  
Simindokht Shirvani Arani ◽  
Mohammad Ghannadi Maragheh
Keyword(s):  
Therapeutic Agent ◽  
In Vivo Generator ◽  
Novel Therapeutic

[166Dy]Dy/166Ho hydroxide macroaggregates: an in vivo generator system for radiation synovectomy

2004 ◽  
Vol 61 (6) ◽  
pp. 1227-1233 ◽  
Author(s):  
G. Ferro-Flores ◽  
O. Hernández-Oviedo ◽  
C. Arteaga de Murphy ◽  
J.I. Tendilla ◽  
F. Monroy-Guzmán ◽  
...  
Keyword(s):  
Radiation Synovectomy ◽  
Generator System ◽  
In Vivo Generator

Preparation of 166Dy/166Ho-EDTMP: a potential in vivo generator system for bone marrow ablation

2004 ◽  
Vol 25 (6) ◽  
pp. 615-621 ◽  
Author(s):  
Martha Pedraza-L??pez ◽  
Guillermina Ferro-Flores ◽  
Consuelo Arteaga de Murphy ◽  
Jose I. Tendilla ◽  
Octavio Villanueva-S??nchez
Keyword(s):  
Bone Marrow ◽  
Generator System ◽  
Bone Marrow Ablation ◽  
In Vivo Generator ◽  
Marrow Ablation

A possible in vivo generator 103Pd/103mRh—Recoil considerations

2008 ◽  
Vol 66 (10) ◽  
pp. 1346-1349 ◽  
Author(s):  
Johann van Rooyen ◽  
Zoltan Szucs ◽  
Jan Rijn Zeevaart
Keyword(s):  
In Vivo Generator

Promising prospects of 44mSc/44Sc as an in vivo generator: Biological evaluation and PET images

2014 ◽  
Vol 41 (7) ◽  
pp. 631 ◽  
Author(s):  
S. Huclier-Markai ◽  
C. Alliot ◽  
J. Rousseau ◽  
N. Chouin ◽  
M. Fani ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
In Vivo Generator

scholarly journals Determination, Modeling and Evaluation of Kinetics of 223Ra Sorption on Hydroxyapatite and Titanium Dioxide Nanoparticles

Materials ◽  
2020 ◽  
Vol 13 (8) ◽  
pp. 1915 ◽  
Author(s):  
Petra Suchánková ◽  
Ekaterina Kukleva ◽  
Karel Štamberg ◽  
Pavel Nykl ◽  
Michal Sakmár ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Titanium Dioxide Nanoparticles ◽  
Sorption Kinetics ◽  
Point Of View ◽  
Particle Therapy ◽  
Radium 223 ◽  
Free Air ◽  
In Vivo Generator ◽  
Kinetics Of

Sorption kinetics of radium on hydroxyapatite and titanium dioxide nanomaterials were studied. The main aim of the current study was to determine the rate-controlling process and the corresponding kinetic model, due to the application of studied nanomaterials as α-emitters’ carriers, and to assess the sorption properties of both materials from the radiopharmaceutical point of view by time regulated sorption experiments on the nanoparticles. Radium-223 was investigated as radionuclide used in targeted alpha particle therapy as an in vivo generator. It was found that the controlling process of the 223Ra sorption kinetics was the diffusion in a reacted layer. Therefore, parameters like particle size, their specific surface area, contact time and temperature played important role. Moreover, the composition of liquid phase, such as pH, the concentration of 223Ra, ionic strength, the presence of complexation ligands, etc., had to be considered. Experiments were conducted under free air conditions and at pH 8 for hydroxyapatite and pH 6 for titanium dioxide in Britton–Robinson buffer. Initial 223Ra concentration was in the range from 10−11 to 10−12 mol/L. It was found that sorption kinetics was very fast (more than 90% in the first hour) in the case of both nanomaterials, so they can be directly used for efficient radium sorption.

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