scholarly journals Female Pattern Hair Loss in Female and Male: A Quantitative Trichoscopic Analysis in Chinese Han Patients

2021 ◽  
Vol 8 ◽  
Author(s):  
Xi Chen ◽  
Xiangqian Li ◽  
Baifu Chen ◽  
Yue Yin ◽  
Jianzhong Zhang ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Hair Loss ◽  
Hair Shaft ◽  
Occipital Area ◽  
Chinese Han ◽  
Hair Density ◽  
Single Hair ◽  
Shaft Diameter ◽  
Female Pattern Hair Loss ◽  
Normal Controls

Objectives: To investigate the trichoscopic features of female pattern hair loss (FPHL) in Chinese Han patients and analyze the difference between male and female patients with FPHL.Materials and Methods: Trichoscopic images were taken in four different scalp areas, including right frontal hairline, vertex, right parietal and occipital areas. Hair density, hair shaft diameter, vellus hair ratio and single hair follicle unit ratio were counted manually and analyzed.Results: Seventy-three subjects were enrolled in this study, including 38 patients with FPHL (28 females and 10 males) and 35 normal controls without hair loss. The hair density and hair shaft diameter of FPHL patients reduced in the whole scalp. Vellus hair ratio and single hair follicle unit ratio were both increased in FPHL compared to normal controls. The vertex was the most affected area and the hair shaft diameter showed the most significant difference. Parietal and occipital area were also affected in FPHL. The reduction or increase was correlated with the severity of Ludwig staging. Very few gender differences were detected in male and female FPHL patients.Conclusion: FPHL patients showed decreased hair density and hair shaft diameter, accompanied by increased vellus hair ratio and single hair follicle unit ratio. Parietal and occipital area can be also affected in FPHL, though not as severe as in vertex area. FPHL in male basically has the same characteristic as those in female patients.Limitation: The main limitation of the study is the small sample size which only enrolled 10 male FPHL patients, in comparison to the female cases. The findings could not be representative of the normal population with the limited sample size.

scholarly journals The Female Pattern Hair Loss: Review of Etiopathogenesis and Diagnosis

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Anja Vujovic ◽  
Véronique Del Marmol
Keyword(s):  
Hair Loss ◽  
Current Knowledge ◽  
Diagnostic Testing ◽  
Clinical Manifestations ◽  
Hair Follicles ◽  
Hair Density ◽  
Female Pattern Hair Loss ◽  
Significant Impairment ◽  
Pattern Distribution

Female pattern hair loss (FPHL) is the most common hair loss disorder in women. Initial signs may develop during teenage years leading to a progressive hair loss with a characteristic pattern distribution. The condition is characterized by progressive replacement of terminal hair follicles over the frontal and vertex regions by miniaturized follicles, that leads progressively to a visible reduction in hair density. Women diagnosed with FPHL may undergo significant impairment of quality of life. FPHL diagnosis is mostly clinical. Depending on patient history and clinical evaluation, further diagnostic testing may be useful. The purpose of the paper is to review the current knowledge about epidemiology, pathogenesis, clinical manifestations, and diagnosis of FPHL.

Hair density, hair diameter and the prevalence of female pattern hair loss

2001 ◽  
Vol 144 (2) ◽  
pp. 297-304 ◽  
Author(s):  
M.P. Birch ◽  
J.F. Messenger ◽  
A.G. Messenger
Keyword(s):  
Hair Loss ◽  
Hair Density ◽  
Female Pattern Hair Loss ◽  
Hair Diameter

Assessment of hair density and caliber in Caucasian and Asian female subjects with female pattern hair loss by using the Folliscope

2012 ◽  
Vol 66 (1) ◽  
pp. 166-167 ◽  
Author(s):  
Bryan Shiu Lun Lee ◽  
Jung-Yi Lisa Chan ◽  
Assaf Monselise ◽  
Kevin McElwee ◽  
Jerry Shapiro
Keyword(s):  
Hair Loss ◽  
Hair Density ◽  
Female Pattern Hair Loss ◽  
Female Subjects

scholarly journals A study on the efficacy of platelet rich plasma for the treatment of patterned hair loss

2020 ◽  
Vol 6 (2) ◽  
pp. 208
Author(s):  
Neerja Puri ◽  
Sushma Thakur
Keyword(s):  
Hair Loss ◽  
Platelet Rich Plasma ◽  
Dermal Papilla ◽  
Hair Shaft ◽  
Novel Therapy ◽  
Dermal Papilla Cells ◽  
Female Pattern Hair Loss ◽  
Average Improvement ◽  
Good Improvement ◽  
Evidence Based Therapy

<p class="abstract"><strong>Background:</strong> Platelet rich plasma (PRP) is a promising and novel therapy new therapy for the treatment of androgenetic alopecia. There are various growth factors in PRP which induce the proliferation of dermal papilla cells.</p><p class="abstract"><strong>Methods:</strong> We selected twenty-five cases of both male and female pattern hair loss for the study.<strong></strong></p><p class="abstract"><strong>Results:</strong> Very good improvement was seen in 8 (32%) patients, good improvement was seen in 12 (48%) patients, average improvement, was seen in 2 (8%) and poor improvement, was seen in 3 (12%) patients. Regarding the side effects of PRP, bruising was seen in 2 (8%), pain was seen in 3 (12%). After 4 months of treatment, average hair count increased by 40% and average hair shaft diameter increased by 56%.</p><p class="abstract"><strong>Conclusions:</strong> PRP is a novel therapy, but is not an evidence-based therapy for the treatment of alopecia.</p>

Clinical, Trichoscopic And Immunohistochemical Evaluation of Autologous Adipose Derived Adult Stem Cell Injection in the Treatment of Female Pattern Hair Loss

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Hoda Ahmed Moneib ◽  
Ghada Fathy Mohamed ◽  
Naglaa Samir Ahmed ◽  
Mahy El-Bassiouny El-Sayed Abou-Noor
Keyword(s):  
Hair Follicle ◽  
Hair Loss ◽  
Adult Stem Cells ◽  
Adult Stem Cell ◽  
Dermal Papilla ◽  
Hair Follicles ◽  
Dermal Papilla Cells ◽  
Female Pattern Hair Loss

Abstract Background Cellular and cell-derived components of adipose-derived tissue for the purposes of dermatologic and aesthetic rejuvenation applications have become increasingly studied and integrated into clinical practice. The hair follicle goes through phases of growth, regression, and quiescence, and it is suspected that adipocytes secrete factors to promote activation of hair follicles dermal papilla cells, increasing migration, and proliferation in vitro; as well as increasing conversion of hair follicles from the telogen to anagen phase in vivo. Objectives Evaluation of efficacy and safety of adipose-derived adult stem cells (ADSCs) injection in hair follicle regeneration in female pattern hair loss (FPHL). Methods 33 patients were included and divided into 3 groups according to Sinclair’s classification according to severity. ADSCs were extracted from lipoaspirate and injected into the frontoparietal scalp. Patients were assessed clinically, trichoscopically and immunohistochemically. Results At week 24, there was improvement of hair thickness and count, both in frontal and occipital areas. Histopathological and immunohistochemical assessment at week 12 showed decrease of perifollicular inflammation and decrease of DKK-1 immunostaining. Conclusion The use of ADSCs in treatment of FPHL in subjects included in this study showed improvement of perifollicular inflammation, in addition to density and thickness of hair.

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