Analysis of Primary Iris and Ciliary Body Cysts in Chinese Patients With Primary Angle Closure Disease

Aim: To investigate the incidence and clinical features of primary iris and ciliary body cysts in Chinese primary angle closure disease (PACD). Patients were evaluated by measuring and analyzing the cysts with an ultrasound biomicroscope (UBM).Methods: The data of patients diagnosed with PACD were reviewed. Demographic data were collected, and the cyst number, size, location, and trabecular-iris angle (TIA) were measured, with the size including the longest diameter (LD) and its corresponding vertical diameter (CVD).Results: A total of 1,334 cases (2,317 eyes) were reviewed, and 409 cysts were found in 131 cases (168 eyes), with an average of 2.43 ± 3.14 cysts per eye. The ages of the patients with cysts ranged from 25 to 80 years, with an average age of 55.24 ± 12.22 years. The detection rate was 7.3%, and the majority of cysts were located in the iridociliary sulcus. Among the 131 patients, 94 had monocular cysts, while binocular cysts occurred in 37 patients. The locations of the cysts in both eyes were mainly in the inferior and temporal quadrants (42.5 and 34.0%, respectively). The cysts were mainly of medium size (49.9%), followed by small cysts (33.3%), large cysts (14.7%) and giant cysts (2.2%). The average LD was 0.68 ± 0.33 mm, and the average CVD was 0.45 ± 0.23 mm. There were no statistically significant differences in the TIA between the cyst area and unaffected area.Conclusions: The incidence of cysts is 7.3% in the PACD population. The cysts are mainly monocular, medium in size, and located in the iridociliary sulcus. Additionally, the cysts were located mainly in the inferior and temporal quadrants. These cysts have little effect on the anterior chamber angle.

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Intraocular lens position and anterior chamber angle changes after cataract extraction in eyes with primary angle-closure glaucoma

Journal of Cataract & Refractive Surgery ◽

10.1016/s0886-3350(97)80089-2 ◽

1997 ◽

Vol 23 (7) ◽

pp. 1109-1113 ◽

Cited By ~ 56

Author(s):

Chang-Hao Yang ◽

Por-Tying Hung

Keyword(s):

Anterior Chamber ◽

Intraocular Lens ◽

Cataract Extraction ◽

Angle Closure Glaucoma ◽

Angle Closure ◽

Anterior Chamber Angle ◽

Primary Angle Closure ◽

Primary Angle Closure Glaucoma ◽

Lens Position ◽

Chamber Angle

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Effect of Phacoemulsification on Anterior Chamber Angle in Eyes with Medically Uncontrolled Filtered Primary Angle-Closure Glaucoma

Journal of Ophthalmology ◽

10.1155/2020/8720450 ◽

2020 ◽

Vol 2020 ◽

pp. 1-6

Author(s):

Chengguo Zuo ◽

Bing Long ◽

Xinxing Guo ◽

Liming Chen ◽

Xing Liu

Keyword(s):

Anterior Chamber ◽

Angle Closure Glaucoma ◽

Angle Closure ◽

Anterior Chamber Angle ◽

Iol Implantation ◽

Anatomical Changes ◽

Primary Angle Closure ◽

Primary Angle Closure Glaucoma ◽

The Mean ◽

Chamber Angle

Purpose. To evaluate the effect of phacoemulsification and intraocular lens (IOLs) implantation in eyes with medically uncontrolled primary angle-closure glaucoma (PACG) previously treated with trabeculectomy and to quantify the anatomical changes in the anterior chamber angle by ultrasound biomicroscopy (UBM). Methods. Forty-four eyes of 37 consecutive patients with medically uncontrolled PACG coexisting cataracts with a surgical history of trabeculectomy were included in this study. Each patient underwent phacoemulsification and IOL implantation. Indentation gonioscopy and UBM were performed preoperatively and then again 3 months after surgery. The main outcome measures were best-corrected visual acuity (BCVA), intraocular pressure (IOP), number of antiglaucoma medications and anatomical changes in the anterior chamber angle. Results. The mean logarithm of the minimum angle of resolution BCVA significantly improved from 0.52 ± 0.30 preoperatively to 0.26 ± 0.23 postoperatively (p<0.001). The mean IOP significantly decreased from 24.33 ± 9.65 mmHg preoperatively to 18.04 ± 7.86 mmHg postoperatively (p<0.05). 001). The median number of antiglaucoma medications decreased from 2 preoperatively to 1 postoperatively (p<0.001). There was no significant difference in the extent of peripheral anterior synechia after the surgery (p>0.05). Some parameters, including anterior central chamber depth, angle opening distance at 500 μm, trabecular-iris angle, and scleral ciliary process angle, were significantly higher after than before surgery (p<0.001). However, the crystalline lens rise was significantly smaller following the surgery (p<0.001). Conclusions. Phacoemulsification and IOL implantation reduced the IOP and improved vision in eyes with medically uncontrolled filtered PACG. The mechanism underlying the outcomes observed following surgery might be related to the anterior chamber deepening, widened drainage angle, and improved aqueous fluid flow to the trabecular meshwork.

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Does an iridotomy provide protection against narrowing of the anterior chamber angle during Valsalva maneuvre in eyes with primary angle closure

Eye ◽

10.1038/sj.eye.6702646 ◽

2007 ◽

Vol 22 (3) ◽

pp. 389-393 ◽

Cited By ~ 13

Author(s):

R Sihota ◽

T Dada ◽

A Aggarwal ◽

G Srinivasan ◽

V Gupta ◽

...

Keyword(s):

Anterior Chamber ◽

Angle Closure ◽

Anterior Chamber Angle ◽

Primary Angle Closure ◽

Chamber Angle

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Ultrasound biomicroscopic quantification of the change in anterior chamber angle following laser peripheral iridotomy in early chronic primary angle closure glaucoma

Eye ◽

10.1038/sj.eye.6702317 ◽

2006 ◽

Vol 21 (6) ◽

pp. 735-741 ◽

Cited By ~ 14

Author(s):

S Kaushik ◽

S Kumar ◽

R Jain ◽

R Bansal ◽

S S Pandav ◽

...

Keyword(s):

Anterior Chamber ◽

Angle Closure Glaucoma ◽

Angle Closure ◽

Anterior Chamber Angle ◽

Laser Peripheral Iridotomy ◽

Primary Angle Closure ◽

Primary Angle Closure Glaucoma ◽

Peripheral Iridotomy ◽

Chamber Angle

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Evaluation of Anterior Chamber Depth and Anterior Chamber Angle Changing After Phacoemulsification in the Primary Angle Close Suspect Eyes

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2019.378 ◽

2019 ◽

Vol 7 (24) ◽

pp. 4297-4300

Author(s):

Anh Tuan Vu ◽

Van Anh Bui ◽

Hai Long Vu ◽

Do Quyet ◽

Than Van Thai ◽

...

Keyword(s):

Anterior Chamber ◽

Intraocular Lens ◽

Anterior Chamber Depth ◽

Angle Closure ◽

Control Group ◽

Anterior Chamber Angle ◽

Interventional Study ◽

Primary Angle Closure ◽

Shallow Anterior Chamber ◽

Chamber Angle

BACKGROUND: Phacoemulsification surgery has the ability to deeply alter the segment anterior morphology, especially in eye with shallow anterior chamber (AC), narrow anterior chamber angle (ACA). However, the changes of anterior chamber depth (ACD) and ACA on the close angle suspect eyes after phacoemulsification have not been mentioned in many studies. So, we conduct this research. AIM: To evaluate the alteration in the ACA and ACD after phacoemulsification in the close angle suspect eyes. METHODS: Interventional study with no control group. Subjects were the primary angle closure suspect (PACS) eyes, that were operated by phacoemulsification with intraocular lens (IOL) at Glaucoma Department of VNIO from December 2017 to October 2018. RESULTS: 29 PACS eyes with cataract were operated by phacoemulsification with intraocular lens. After 3 months of monitoring, the average ACD augmented from 2.082 ± 0.244 to 3.673 ± 0.222 mm. AOD500 increase from 0.183 ± 0.088 to 0.388 ± 0.132 μm, AOD750 increased from 0.278 ± 0.105 to 0.576 ± 0.149 μm. The TISA500 enlarged from 0.068 ± 0.033 to 0.140 ± 0.052 mm2, TISA750 enlarged from 0.125 ± 0.052 to 0.256 ± 0.089 mm2 at the third month (p < 0.01). CONCLUSION: Phacoemulsification surgery increases the ACD and enlarged the angle in the PACS eyes.

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REVIEW CLINICAL CHARACTERISTICS AND TREATMENT OUTCOME OF PRIMARY ANGLE CLOSURE GLAUCOMA BY USED ND: YAG LASER PERIPHERAL IRIDOTOMY

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2012.2.3 ◽

2012 ◽

pp. 18-24

Author(s):

Huu Quoc Nguyen Nguyen ◽

Nam Trung Nguyen

Keyword(s):

Anterior Chamber ◽

Angle Closure Glaucoma ◽

Angle Closure ◽

Anterior Chamber Angle ◽

Yag Laser ◽

Primary Angle Closure ◽

Primary Angle Closure Glaucoma ◽

Low Levels ◽

Angle Width ◽

Chamber Angle

Objectives: To review the clinical characteristics of primary angle closure glaucoma and the outcome of Nd: YAG laser peripheral iridoctom. Materials and Methods: Prospective study of 46 eyes underwent iridotomy, evaluation of the intraocular pressure and the anterior chamber angle within 2 weeks, 1 month, 3 months & 6 months after treatment. Results: The majority of subjects were females 73.33%, over 60 years of age (80%), blurred vision and decrease visual acuity when the patient were hospitalized (43.48%), 19.65% eye pain, physical symptoms are mainly shallow anterior chamber or pupillary reflexes relaxing lazy. Embryonic glaucoma and chronic angle glaucoma distribution percentage 69.57%. Mean IOP after 2 weeks X = 18.17 ± 1.37 mmHg, 7.66 mmHg lower than before treatment. Anterior chamber angle width increased significantly after 2 weeks of treatment. And no significant changer after 1 month, 3 months & 6 months. There was a precise inverse relation between anterior chamber angle width before treatment with low levels of IOP after treatment, and there was a precise proportional relation between the low levels of IOP with the increase of chamber angle width after treatment. Conclusion: Nd: YAG laser iridotomy is effective in widening the anterior chamber angle and lowering intraocular pressure in primary angle closure glaucoma.

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New capabilities of optical coherence tomography in the diagnostics of primary angle-closure glaucoma

National Journal glaucoma ◽

10.53432/2078-4104-2021-20-2-14-22 ◽

2021 ◽

Vol 20 (2) ◽

pp. 14-22

Author(s):

V. P. Erichev ◽

R. P. Poleva ◽

Kh. Hadiri

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Angle Closure Glaucoma ◽

Angle Closure ◽

Ophthalmological Examination ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Primary Angle Closure ◽

Primary Angle Closure Glaucoma ◽

Chamber Angle

INTRODUCTION. Recently, posterior vitreous detachment (PVD) was suggested as a fundamental pathologic process in primary angle-closure glaucoma (PACG) in morphologically predisposed patients with anatomically narrow anterior chamber angle.PURPOSE. To study the role of PVD in the development and clinical manifestation of PACG in anatomically predisposed eyes and to assess the capabilities of posterior segment optical coherence tomography (PS-OCT) in PACG diagnostics.MATERIALS AND METHODS. Thirty eyes with newly diagnosed stage I-II PACG and thirty eyes predisposed to PACG (with narrow anterior chamber angle without glaucoma signs) were enrolled in the study. All patients underwent ophthalmological examination, Hyams test, ocular ultrasound (OU) and PS-OCT.RESULTS. PVD with retrohyaloid space (RHS) formation was revealed in all PACG eyes. Positive Hyams test was in 86.67% eyes with PACG, and 13.33% were negative. All the eyes with PVD as a result of Hyams test experienced RHS enhancement correlating with IOP rise. Despite the negative results of Hyams test in some PACG eyes with PVD — glaucomatous optic neuropathy signs were present. Possible causes are discussed.PVD with RHS formation was revealed in 53.33% predisposed to PACG eyes — all with positive result of Hyams test. The other 46.67% eyes predisposed to PACG had negative Hyams test, no PVD and no RHS.CONCLUSION. Obtained results confirm a new theory of PACG etiopathogenesis suggesting PVD with PGS to be the essential mechanism of POAG development in morphologically predisposed eyes. PS-OCT appears to be crucial in PACG early diagnostics.

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