scholarly journals Stress-Induced Enhancement of Ethanol Intake in C57BL/6J Mice with a History of Chronic Ethanol Exposure: Involvement of Kappa Opioid Receptors

Author(s):  
Rachel I. Anderson ◽  
Marcelo F. Lopez ◽  
Howard C. Becker
1990 ◽  
Vol 69 (10) ◽  
pp. 1674-1677 ◽  
Author(s):  
R.J. Henry ◽  
M.M. Ishii ◽  
R.M. Quock

The purpose of this study was to determine whether sensitivity to nitrous oxide analgesia was altered by chronic ethanol exposure. Control mice exposed to 25%, 50%, and 75% nitrous oxide in oxygen demonstrated a concentration-related analgesic effect, as measured by the acetic acid abdominal constriction test. Other mice previously exposed to ethanol vapors for 72 h exhibited a significantly reduced sensitivity to nitrous oxide analgesia. The dose-response curve of the chronic ethanol-exposed group was shifted to the right of that of the control mice. These findings suggest the possibility that subjects with a history of alcohol abuse might have reduced responsiveness to nitrous oxide in a clinical setting.


2016 ◽  
Vol 6 (9) ◽  
Author(s):  
Ashlee Van't Veer ◽  
Karen L. Smith ◽  
Bruce M. Cohen ◽  
William A. Carlezon ◽  
Anita J. Bechtholt

Alcohol ◽  
2008 ◽  
Vol 42 (6) ◽  
pp. 493-497 ◽  
Author(s):  
Linda C. Saland ◽  
Juliana B. Chavez ◽  
David C. Lee ◽  
Raphael R. Garcia ◽  
Kevin K. Caldwell

2012 ◽  
Vol 71 (3) ◽  
pp. 232-238 ◽  
Author(s):  
Richard M. van Rijn ◽  
Daniela I. Brissett ◽  
Jennifer L. Whistler

Analgesia ◽  
1995 ◽  
Vol 1 (4) ◽  
pp. 557-560 ◽  
Author(s):  
Á Márki ◽  
F. Ötvös ◽  
G. Tóth ◽  
S. Hosztafi ◽  
A. Borsodi

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