scholarly journals Summation and Cancellation Effects on QRS and ST-Segment Changes Induced by Simultaneous Regional Myocardial Ischemia

2018 ◽  
Vol 9 ◽  
Author(s):  
Miquel Vives-Borrás ◽  
Esther Jorge ◽  
Gerard Amorós-Figueras ◽  
Xavier Millán ◽  
Dabit Arzamendi ◽  
...  
Keyword(s):  
Myocardial Ischemia ◽  
St Segment ◽  
Regional Myocardial Ischemia

scholarly journals Changes in intramyocardial ST segment voltage and gas tensions with regional myocardial ischemia in the dog.

1975 ◽  
Vol 37 (4) ◽  
pp. 455-463 ◽  
Author(s):  
S F Khuri ◽  
J T Flaherty ◽  
J B O'Riordan ◽  
B Pitt ◽  
R K Brawley ◽  
...  
Keyword(s):  
Myocardial Ischemia ◽  
St Segment ◽  
Regional Myocardial Ischemia

Routine use of antegrade cardioplegia underestimates the risk of regional myocardial ischemia especially in right coronary disease

2006 ◽  
Vol 54 (S 1) ◽  
Author(s):  
J Strauch ◽  
U Franke ◽  
J Wippermann ◽  
M Kaluza ◽  
T Wahlers
Keyword(s):  
Myocardial Ischemia ◽  
Coronary Disease ◽  
Regional Myocardial Ischemia ◽  
Antegrade Cardioplegia

Functional assessment of myocardial ischemia by intracoronary electrocardiogram

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
M.R Bigler ◽  
F Praz ◽  
G.C.M Siontis ◽  
M Stoller ◽  
R Grossenbacher ◽  
...  
Keyword(s):  
Myocardial Ischemia ◽  
Primary Study ◽  
Coronary Perfusion ◽  
Funding Source ◽  
Maximal Heart Rate ◽  
Fractional Flow ◽  
Coronary Syndrome ◽  
Flow Reserve ◽  
St Segment ◽  
Coronary Lesions

Abstract Background In patients with chronic coronary syndrome (CCS), percutaneous coronary intervention (PCI) targets hemodynamically significant stenoses, i.e., those thought to cause ischemia. The hemodynamic severity of a coronary stenosis increases with its tightness and with the myocardial mass of viable myocardium downstream of the stenosis. Besides the structural angiographic approach, assessment of functional relevance by pressure measurements (fractional flow reserve, FFR; instantaneous wave-free ratio, iFR) is recommended. However, visual angiographic assessment continues to dominate the treatment decisions for intermediate coronary lesions. Conversely, intracoronary ECG (icECG) potentially provides an inexpensive, sensitive and direct measure of myocardial ischemia. Purpose The goal of this study was to test the accuracy of intracoronary ECG during pharmacologic inotropic stress to determine coronary lesion severity in comparison to established physiologic indices (FFR/iFR) as well as with quantitatively determined percent diameter stenosis (%S) using biplane coronary angiography. Method This was a prospective, open-label study in patients with CCS. The primary study end point was the maximal change in icECG ST-segment shift during pharmacologic inotropic stress induced by dobutamine plus atropine obtained within 1 minute after the point of maximal heart rate (estimated by the formula 220 - age). IcECG was acquired by attaching an alligator clamp to the angioplasty guidewire positioned downstream of a stenosis. For the pressure-derived ratios, i.e. FFR and iFR, the coronary perfusion pressure downstream of a lesion as well as the aortic pressure were continuously recorded. Results One hundred patients were included in the study. Pearson-Correlation coefficient was significant between icECG and all three comparators (%S p<0.001, iFR p<0.001, FFR p<0.001). Using the FFR threshold of 0.80 defining coronary hemodynamic significance, ROC-analysis of the absolute icECG ST-segment shift showed an area under the curve (AUC) of 0.708±0.053 (p=0.0001, n=100, FFR<0.80 n=41). AUC for iFR was 0.919±0.030 (p<0.0001), for percent diameter stenosis it was 0.867±0.036 (p<0.0001). Conclusions During pharmacologic inotropic stress, intracoronary ECG ST-segment shift provides specific evidence for regional myocardial ischemia irrespective of the etiology and thus, provides an additional (patho-)physiologic information for decision making in borderline coronary lesions. Funding Acknowledgement Type of funding source: Foundation. Main funding source(s): Swiss Heart Foundation

scholarly journals Electrocardiographic scores of severity and acuteness of myocardial ischemia predict myocardial salvage in patients with anterior ST-segment elevation myocardial infarction

2018 ◽  
Vol 51 (2) ◽  
pp. 195-202 ◽  
Author(s):  
Yama Fakhri ◽  
Maria Sejersten ◽  
Mikkel Malby Schoos ◽  
Henrik Steen Hansen ◽  
Jean-Luc Dubois-Rande ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Myocardial Ischemia ◽  
Myocardial Salvage ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment

Dobutamine-Induced Myocardial Ischemia and ST-Segment Elevation in Collateral-Dependent Myocardium

2013 ◽  
Vol 112 (9) ◽  
pp. 1293-1297 ◽  
Author(s):  
Jamshid Shirani ◽  
Shruthi Pranesh ◽  
Kimia Menhaji ◽  
Vlad Cotarlan ◽  
Alessandra Brofferio
Keyword(s):  
Myocardial Ischemia ◽  
St Segment Elevation ◽  
St Segment

The Effects of Intravenous Clonidine on Regional Myocardial Function in a Canine Model of Regional Myocardial Ischemia

1994 ◽  
Vol 78 (6) ◽  
pp. 1047???1052 ◽  
Author(s):  
Masashi Kono ◽  
Shigeho Morita ◽  
Takayuki Hayashi ◽  
Mieko Saitoh ◽  
Nobuo Fuke ◽  
...  
Keyword(s):  
Myocardial Ischemia ◽  
Myocardial Function ◽  
Canine Model ◽  
Regional Myocardial Function ◽  
Regional Myocardial Ischemia

Myosin Light Chain Phosphorylation during Regional Myocardial Ischemia

1983 ◽  
pp. 479-487
Author(s):  
P. Cummins ◽  
D. M. Yellon ◽  
D. J. Hearse
Keyword(s):  
Myocardial Ischemia ◽  
Light Chain ◽  
Myosin Light Chain ◽  
Myosin Light Chain Phosphorylation ◽  
Regional Myocardial Ischemia
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