scholarly journals Spectrophotometric Determination of Mesalazine, Carbamazepine and Diclofenac Sodium in Pharmaceutical Preparations by Using Nile Blue Dye

2019 ◽  
Vol 28 (4) ◽  
pp. 48-69
Author(s):  
Abdussamed Saeed ◽  
Elham Salih
Keyword(s):  
Spectrophotometric Determination ◽  
Nile Blue ◽  
Diclofenac Sodium ◽  
Pharmaceutical Preparations ◽  
Blue Dye

scholarly journals SPECTROPHOTOMETRIC DETERMINATION OF SOME PHARMACEUTICAL COMPOUNDS USING 2,2-DIPHENYL-1-PICRYLHYDRAZYL

2000 ◽  
Vol 68 (4) ◽  
pp. 403-419 ◽  
Author(s):  
Hesham Salem
Keyword(s):  
Hydrogen Atom ◽  
Spectrophotometric Determination ◽  
Diclofenac Sodium ◽  
Pharmaceutical Preparations ◽  
Standard Addition ◽  
Pharmaceutical Compounds ◽  
Radical Coupling ◽  
Violet Color ◽  
Good Agreement

A simple, rapid and sensitive spectrophotometric procedure for the assay of some drugs has been developed. The method is based on the reaction of the studied drugs with 2,2-diphenyl-1-picrylhydrazyl (DPPH). The latter is employed to abstract a hydrogen atom from the drugs thereby promoting a process of radical coupling. This results in a reduction of the violet color of DPPH with the formation of the yellow colored 2,2-diphenyl-1-picrylhydrazine (DPPH2). The decrease in the intensity of the violet color is used to measure the concentration of the drugs. All measurements are made at λ= 520 nm on methanolic solutions of the reagent and drugs. Beer's law is obeyed in the ranges of 5-30 µg/ml (for aceclofenac, diclofenac sodium and thiaprofenic acid), 2-15 µg/ml (for tenoxicam, furosemide and lansoprazole) and 2-12 µg/ml (for benoxinate hydrochloride and ritodrine). The validity of the method was tested by carrying out standard addition procedure analyzing the studied drugs in pure form as well as in their pharmaceutical preparations without interference from common additives. Results of the proposed methods are in good agreement with those of the official or reported methods.

scholarly journals Utilização dos métodos automáticos em fluxos com detecção espectrofotométrica na determinação de diclofenaco de sódio em formulações farmacêuticas e fluidos corporais

2019 ◽  
Vol 48 (1) ◽  
pp. 29-43
Author(s):  
Paulo Roberto Barrros Gomes ◽  
Victor Elias Mouchrek Filho ◽  
Rayone Wesly Santos de Oliveira ◽  
Adriana Pereira Everton ◽  
Jonas Batista Reis ◽  
...  
Keyword(s):  
Spectrophotometric Determination ◽  
Spectrophotometric Method ◽  
Flow System ◽  
Diclofenac Sodium ◽  
Pharmaceutical Preparations ◽  
Pharmaceutical Formulations ◽  
Sequential Injection Analysis ◽  
Sequential Injection ◽  
Para Determinar

Este trabalho descreveu e comparou quatro estudos entre si que utilizaram métodos automáticos em fluxo com detecção espectrofotométrica e a reação de oxidação do diclofenaco para determinar diclofenaco em formulações farmacêuticas e fluidos corporais. Para isso, utilizamos os seguintes artigos: Versatility of a multicommuted flow system in the spectrometric determination of three analytes, Sequential injection spectrophotometric method for the assay of anti-inflammatory diclofenac sodium in pharmaceutical preparations, Screening of conditions controlling spectrophotometric sequential injection analysis e Sequential injection spectrophotometric determination of diclofenac in urine and pharmaceutical formulations e detalhamos as metodologias empregadas, os resultados, conclusões obtidas e comparamos entre eles os limites de detecção, desvio padrão relativo e a frequência analítica. Os resultados mostraram diferenças significativas entre métodos empregados e a utilização do Sistema automático do tipo Análise por Injeção Sequencial, apesar deste possuir menor frequência analítica.

Spectrophotometric Determination of Lignocaine in Pure Form and in Pharmaceutical Preparations

1997 ◽  
Vol 30 (15) ◽  
pp. 2743-2753 ◽  
Author(s):  
M. S. Rizk ◽  
Y M Issa ◽  
A F Shoukry ◽  
E M Atia
Keyword(s):  
Spectrophotometric Determination ◽  
Pharmaceutical Preparations ◽  
Pure Form

Spectrophotometric determination of Metronidazole and Secnidazole in pharmaceutical preparations based on the formation of dyes

2006 ◽  
Vol 70 (3) ◽  
pp. 259-262 ◽  
Author(s):  
T SAFFAJ ◽  
M CHARROUF ◽  
A ABOURRICHE ◽  
Y ABOUD ◽  
A BENNAMARA ◽  
...  
Keyword(s):  
Spectrophotometric Determination ◽  
Pharmaceutical Preparations

scholarly journals Spectrophotometric Determination of Epinephrine in Pharmaceutical Preparations Using Praseodymium as Mediating Metals

2011 ◽  
Vol 8 (1) ◽  
pp. 110-117 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Relative Error ◽  
Spectrophotometric Determination ◽  
Spectrophotometric Method ◽  
Pharmaceutical Preparations ◽  
Direct Methods ◽  
Orange Yellow ◽  
Sensitive Spectrophotometric Method

A simple, accurate and sensitive spectrophotometric method for the determinaion of epinephrine is described . The method is based on the coordination of Pr (III) with epinephrine at pH 6. Absorbance of the resulting orange yellow complex is measured at 482 nm . A graph of absorbance versus concentrations shows that beer 's low is obeyed over the concentration range (1-50)mg.ml-1 of epinephrine with molar absorpitivity of ( 2.180x103 L.mol-1.cm-1 ), a sandell sensitivity of (0.084 mg.cm-2 ), a relative error of (-2.83%) , a corrolation coffecient (r= 0.9989) and recovery % ( 97.03 ± 0.75 ) depending on the concentration.This method is applied to analyse EP in several commercially available pharmaceutical preparations using direct methods .All statistical calculations are implemented via a Minitab software version 11.

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