scholarly journals Imaging the Human Thyroid Using Three-Dimensional Diffuse Optical Tomography: A Preliminary Study

2021 ◽  
Vol 11 (4) ◽  
pp. 1670
Author(s):  
Tetsuya Mimura ◽  
Shinpei Okawa ◽  
Hiroshi Kawaguchi ◽  
Yukari Tanikawa ◽  
Yoko Hoshi

Thyroid cancer is usually diagnosed by ultrasound imaging and fine-needle aspiration biopsy. However, diagnosis of follicular thyroid carcinomas (FTC) is difficult because FTC lacks nuclear atypia and a consensus on histological interpretation. Diffuse optical tomography (DOT) offers the potential to diagnose FTC because it can measure tumor hypoxia, while image reconstruction of the thyroid is still challenging mainly due to the complex anatomical features of the neck. In this study, we attempted to solve this issue by creating a finite element model of the human neck excluding the trachea (a void region). By reconstruction of the absorption coefficients at three wavelengths, 3D tissue oxygen saturation maps of the human thyroid are obtained for the first time by DOT.

2012 ◽  
Vol 17 (12) ◽  
pp. 126009 ◽  
Author(s):  
Kirstin Baum ◽  
Raimo Hartmann ◽  
Tobias Bischoff ◽  
Jan O. Oelerich ◽  
Stephan Finkensieper ◽  
...  

2014 ◽  
Vol 22 (3) ◽  
Author(s):  
Caifang Wang

Abstract.Diffuse optical tomography (DOT) is an optical imaging modality, which provides the spatial distribution of the optical parameters inside a random medium. A propagation back-propagation method named EM-like reconstruction method for stationary DOT problem has been proposed yet. This method is really time consuming. Hence the ordered-subsets (OS) technique for this reconstruction method is studied in this paper. The boundary measurements of DOT are grouped into nonoverlapping and overlapping ordered sequence of subsets with random partition, sequential partition and periodic partition, respectively. The performance of OS methods is compared with the standard EM-like reconstruction method with two-dimensional and three-dimensional numerical experiments. The numerical experiments indicate that reconstruction of nonoverlapping subsets with periodic partition, overlapping subsets with periodic partition and standard EM-like method provide very similar acceptable reconstruction results. However, reconstruction of nonoverlapping subsets with periodic partition spends a minimum of time to get proper results.


2008 ◽  
Vol 27 (6) ◽  
pp. 752-765 ◽  
Author(s):  
G. Boverman ◽  
E.L. Miller ◽  
D.H. Brooks ◽  
D. Isaacson ◽  
Qianqian Fang ◽  
...  

2009 ◽  
Author(s):  
Qizhi Zhang ◽  
Yiyong Tan ◽  
Zhen Yuan ◽  
Eric Sobel ◽  
Huabei Jiang

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