scholarly journals Seafloor Classification in a Sand Wave Environment on the Dutch Continental Shelf Using Multibeam Echosounder Backscatter Data

Geosciences ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 142 ◽  
Author(s):  
Leo Koop ◽  
Alireza Amiri-Simkooei ◽  
Karin J. van der Reijden ◽  
Sarah O’Flynn ◽  
Mirjam Snellen ◽  
...  

High resolution maps of sandy seafloors are valuable to understand seafloor dynamics, plan engineering projects, and create detailed benthic habitat maps. This paper presents multibeam echosounder backscatter classification results of the Brown Bank area of the North Sea. We apply the Bayesian classification method in a megaripple and sand wave area with significant slopes. Prior to the classification, corrections are implemented to account for the slopes. This includes corrections on the backscatter value and its corresponding incident angle. A trade-off in classification resolutions is found. A higher geo-acoustic resolution is obtained at the price of losing spatial resolution, however, the Bayesian classification method remains robust with respect to these trade-off decisions. The classification results are compared to grab sample particle size analysis and classified video footage. In non-distinctive sedimentary environments, the acoustic classes are not attributed to only the mean grain size of the grab samples but to the full spectrum of the grain sizes. Finally, we show the Bayesian classification results can be used to characterize the sedimentary composition of megaripples. Coarser sediments were found in the troughs and on the crests, finer sediments on the stoss slopes and a mixture of sediments on the lee slopes.

Author(s):  
EL- Assal I. A. ◽  
Retnowati .

Objective of the present investigation was enthused by the possibility to develop solid lipid nanoparticles (SLNs) of hydrophilic drug acyclovir. Also study vitro and vivo drug delivery. Methods: Drug loaded SLNs (ACV-SLNs) were prepared by high pressure homogenization of aqueous surfactant solutions containing the drug-loaded lipids in the melted or in the solid state with formula optimization study (Different lipid concentration, drug loaded, homogenization / stirring speed and compritol 888ATO: drug ratio). ACV - SLN incorporated in cream base. The pH was evaluated and rheological study. Drug release was evaluated and compared with simple cream- drug, ACV – SLN with compritol 888ATO and marketed cream. The potential of SLN as the carrier for dermal delivery was studied. Results: Particle size analysis of SLNs prove small, smooth, spherical shape particle ranged from 150 to 200 nm for unloaded and from 330 to 444 nm for ACV loaded particles. The EE% for optimal formula is 72% with suitable pH for skin application. Rheological behavior is shear thinning and thixotropic. Release study proved controlled drug release for SLNs especially in formula containing compritol88 ATO. Stability study emphasized an insignificant change in SLNs properties over 6 month. In-vivo study showed significantly higher accumulation of ACV in stratum corneum, dermal layer, and receptor compartment compared with blank skin. Conclusion: AVC-loaded SLNs might be beneficial in controlling drug release, stable and improving dermal delivery of antiviral agent(s).


Circular ◽  
1985 ◽  
Author(s):  
Lawrence J. Poppe ◽  
A.H. Eliason ◽  
J.J. Fredericks

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