scholarly journals Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions

2021 ◽  
Vol 10 (4) ◽  
pp. 701
Author(s):  
Pierleone Lucatelli ◽  
Mario Corona ◽  
Leonardo Teodoli ◽  
Piergiorgio Nardis ◽  
Alessandro Cannavale ◽  
...  
Keyword(s):  
Clinical Success ◽  
Embolic Agent ◽  
Fluoroscopic Guidance ◽  
Gastric Bleeding ◽  
Percutaneous Embolization ◽  
Safety And Efficacy ◽  
Liquid Embolic ◽  
Internal Iliac ◽  
Liquid Embolic Agent ◽  
Single Intervention

Objective: To evaluate the safety and efficacy of the Phil liquid embolic agent in non-neurological embolization procedures. M&M: Thirty-five patients with a mean age of 62.5 years underwent percutaneous embolization using Phil for the treatment of visceral arterial bleedings in 20/35 patients (including three gluteal, one bladder, two superior mesenteric, three epigastric, one deep femoral, five internal iliac, four intercostal, and one lingual arteries), splanchnic pseudoaneurysms in 11/35 patients (including three hepatic, five splenic, and three renal arteries), pancreatic bleeding metastasis in 1/35 patient, and gastric bleeding varices in 3/35 patients. Phil is composed of a non-adhesive copolymer dissolved in DMSO (Anhydrous Dimethyl Sulfoxide) with different viscosity. Procedures were performed slowly under continuous fluoroscopic guidance to avoid embolization of non-target vessels. Results: Clinical success was obtained with a single intervention in 34 cases (97.15%), while a repeated procedure was required in one case (2.85%). No technical complications nor non-target embolization occurred. A case of post-embolic syndrome was noted (2.85%) in one patient. DMSO administration-related pain was successfully controlled by medical therapy. Conclusion: Phil can be considered a safe and effective embolic agent for the treatment of non-neurologic bleeding.

scholarly journals Successful embolisation of pelvic fistulating vessels to the prostate arising after TURP – a rare cause of postoperative bleeding

2020 ◽  
Vol 102 (3) ◽  
pp. e60-e62
Author(s):  
JF Donati-Bourne ◽  
S Morris ◽  
S Nour ◽  
IJ McCafferty ◽  
Y Smith
Keyword(s):  
Postoperative Bleeding ◽  
Embolic Agent ◽  
Standard Management ◽  
Core Skill ◽  
Liquid Embolic ◽  
Prostatic Enlargement ◽  
Internal Iliac ◽  
Liquid Embolic Agent ◽  
The Right ◽  
Pelvic Varices

Transurethral resection of the prostate (TURP) is considered the gold-standard operation to treat lower urinary tract symptoms due to benign prostatic enlargement in men. Postoperative bleeding is a recognised complication and managing it is a core skill required by attending urologists. We report a rare case of postoperative bleeding caused by fistulating vessels to the prostate which developed after TURP. These fistulas arose from the right internal iliac vessels and communicated with pre-existing pelvic varices affecting the right paraprostaticand seminal vesicle tissues. The fistulating vessels were successfully embolised with liquid embolic agent. Surgeons should be aware that persisting haemorrhage can occur post-TURP from the rare presence of fistulating vessels communicating with pelvic varices. Early computed tomography angiographic assessment is warranted in cases where bleeding is prolonged and refractory to standard management in view of timely referral for percutaneous embolisation.

Minimally Invasive Treatment of a Bronchobiliary Fistula that Developed Secondary to Chemotherapy-induced Stricturing

2018 ◽  
Vol 2 ◽  
pp. 13
Author(s):  
Samuel L Rice ◽  
Patrick H Dinkelborg ◽  
Leah R Flood ◽  
William Alago
Keyword(s):  
Minimally Invasive ◽  
Biliary Tree ◽  
Embolic Agent ◽  
Fistula Tract ◽  
Invasive Treatment ◽  
Bronchobiliary Fistula ◽  
Percutaneous Embolization ◽  
Liquid Embolic ◽  
Bronchial System ◽  
Liquid Embolic Agent

A bronchobiliary fistula (BBF) is a rare abnormal communication between the biliary tree and bronchial system. The majority of cases are the result of biliary obstruction or injury, with the major symptomatology of cough and biliptysis. The initial management of BBFs is variable but aims to decompress the biliary system allowing for diversion and passive healing of the fistula tract. Definitive management is with surgical fistulectomy. New minimally invasive therapeutic approaches utilizing endoscopic or percutaneous methodology have been described with some success. We present the successful treatment of a BBF that developed secondary to chemotherapy-induced biliary stricturing (CIBS) with a novel percutaneous embolization approach using a vascular plug and liquid embolic agent.

scholarly journals Percutaneous Embolization of Scalp Arteriovenous Malformation Using New Liquid Embolic Agent, SQUID: A Technical Report

2017 ◽  
Vol 01 (03) ◽  
pp. 171-174 ◽  
Author(s):  
Santhosh Kannath ◽  
Jayadevan Rajan
Keyword(s):  
Vascular Malformations ◽  
Surgical Excision ◽  
Percutaneous Treatment ◽  
Primary Treatment ◽  
Embolic Agent ◽  
Surgical Approaches ◽  
Percutaneous Embolization ◽  
Liquid Embolic ◽  
Complete Obliteration ◽  
Liquid Embolic Agent

AbstractScalp arteriovenous malformations (AVMs) are rare extracranial vascular malformations that are traditionally treated by surgical excision or by combined endovascular-surgical approaches. We describe percutaneous treatment of scalp AVM, using a new liquid embolic agent, SQUID. Because of its nonadhesive property, prolonged injection and complete obliteration of scalp AVM is feasible. The cast formed is aesthetically appealing to the patient, and it may obviate the need for further surgical excision. It could be considered as the primary treatment option for patients unwilling for surgery.

scholarly journals Concomitant Transarterial and Transvenous Embolization of a Pelvic Arteriovenous Malformation Using a New Liquid Embolic Agent, Squid-12 and Detachable Coils

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Aysun Erbahceci Salik ◽  
Filiz Islim ◽  
Ahmet Akgul ◽  
Barbaros Erhan Cil
Keyword(s):  
Embolic Agent ◽  
Transvenous Embolization ◽  
Ethylene Vinyl Alcohol ◽  
Lower Viscosity ◽  
Liquid Embolic ◽  
Internal Iliac ◽  
Liquid Embolic Agent ◽  
Detachable Coils ◽  
Multiple Feeding ◽  
The Right

We describe a complex congenital pelvic AVM with multiple feeding arteries arising from the side branches of the right internal iliac artery and a single draining vein in a male patient. Concomitant transarterial and transvenous embolization with a new liquid embolic agent Squid-12 and metallic coils enabled a complete embolization at a single session. Squid-12 is composed of ethylene vinyl alcohol copolymers and its lower viscosity makes it a promising agent for the treatment of AVMs. The patient showed prompt resolution of the symptoms and complete devascularization of the AVM lesion was persisted on the 1-month control angiography. The patient was asymptomatic on the 6th month follow-up.

scholarly journals Giant Hepatic Artery Aneurysm Associated with Immunoglobulin G4-Related Disease Successfully Treated Using a Liquid Embolic Agent

2015 ◽  
Vol 16 (4) ◽  
pp. 953 ◽  
Author(s):  
Michele Rossi ◽  
Edoardo Virgilio ◽  
Florindo Laurino ◽  
Gianluigi Orgera ◽  
Paolo Menè ◽  
...  
Keyword(s):  
Hepatic Artery ◽  
Artery Aneurysm ◽  
Embolic Agent ◽  
Hepatic Artery Aneurysm ◽  
Immunoglobulin G4 ◽  
Related Disease ◽  
Liquid Embolic ◽  
Liquid Embolic Agent

scholarly journals Investigation of a New Version of the Liquid Embolic Agent PHIL with Extra-Low-Viscosity in an Endovascular Embolization Model

2018 ◽  
Vol 39 (9) ◽  
pp. 1696-1702 ◽  
Author(s):  
D.F. Vollherbst ◽  
R. Otto ◽  
M. Hantz ◽  
C. Ulfert ◽  
H.U. Kauczor ◽  
...  
Keyword(s):  
Endovascular Embolization ◽  
Embolic Agent ◽  
Low Viscosity ◽  
Liquid Embolic ◽  
Liquid Embolic Agent

scholarly journals Re-treatment of residual aneurysms after flow diversion: An experimental study

2018 ◽  
Vol 31 (3) ◽  
pp. 270-279 ◽  
Author(s):  
Robert Fahed ◽  
Tim E Darsaut ◽  
Marc Kotowski ◽  
Igor Salazkin ◽  
Jean Raymond
Keyword(s):  
Flow Diverter ◽  
Artery Occlusion ◽  
Flow Diversion ◽  
Embolic Agent ◽  
Parent Artery ◽  
Arterial Lumen ◽  
Parent Artery Occlusion ◽  
Liquid Embolic ◽  
Liquid Embolic Agent ◽  
Flow Diverters

Aim Flow diverters are increasingly used to treat aneurysms, but treatment is not always effective. The management of aneurysms that fail to occlude following flow diversion is problematic. We aimed to reproduce failures in an animal model and study re-treatment with additional flow diverters alone or with flow diverters and liquid embolic agent. Material and methods Twenty wide-necked aneurysms were created at the carotid-lingual bifurcation in 10 dogs, and were treated with flow diverters 4–6 weeks later. Follow-up angiography was performed at three months. Suitable residual aneurysms were randomly allocated: re-treatment with flow diverters alone ( n = 6), or with the injection of liquid embolic between two layers of flow diverters ( n = 4) or no re-treatment ( n = 2). Angiography was repeated three months later, followed by euthanasia, photography and pathology. Results Patent wide-necked aneurysms were produced in 17/20 attempts (85%); three months after flow diversion there were 15/17 (88%) residual aneurysms. In three cases, re-treatment was not possible because the flow diverter had prolapsed into the aneurysm, leaving 12 aneurysms to study. Re-treated aneurysms showed improved angiographic results at six months (median score of 2; P = 0.03), but residual aneurysms were present in all cases. Parent artery occlusion occurred in two aneurysms treated with flow diverter plus liquid embolic. At pathology, aneurysms were only partially filled with thrombus; leaks through the flow diverters were found in the neointima connecting the arterial lumen to residual aneurysms. Conclusion Re-treatment of residual flow-diverted experimental aneurysms with additional flow diverters did not lead to aneurysm occlusion.

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