scholarly journals An Improved High Yield Total Synthesis and Cytotoxicity Study of the Marine Alkaloid Neoamphimedine: An ATP-Competitive Inhibitor of Topoisomerase IIα and Potent Anticancer Agent

Marine Drugs ◽  
2014 ◽  
Vol 12 (9) ◽  
pp. 4833-4850 ◽  
Author(s):  
Linfeng Li ◽  
Adedoyin Abraham ◽  
Qiong Zhou ◽  
Hadi Ali ◽  
Jeremy O'Brien ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Anticancer Agent ◽  
Competitive Inhibitor ◽  
High Yield ◽  
Topoisomerase Iiα ◽  
Marine Alkaloid

Formal total synthesis of (±)-7-deoxycylindrospermopsin and its 8-epi isomer

2021 ◽  
Author(s):  
Si-Qing Wang ◽  
Wei-Yi Qi ◽  
Xue-Song Yin ◽  
Bing-Feng Shi
Keyword(s):  
Total Synthesis ◽  
Guanidine Group ◽  
Marine Alkaloid

7-Deoxycylindrospermopsin is a member of cylindrospermopsin marine alkaloid containing a cyclic guanidine group. Herein, we present a concise formal total synthesis of (±)-7-deoxycylindrospermopsin in 14 steps from commercailly available 4-methoxypyridine....

First Total Synthesis of a Fluorinated Calystegin

2010 ◽  
Vol 65 (4) ◽  
pp. 445-451 ◽  
Author(s):  
René Csuk ◽  
Erik Prell ◽  
Stefan Reißmann ◽  
Claudia Korb
Keyword(s):  
Total Synthesis ◽  
Ring Opening ◽  
Competitive Inhibitor ◽  
Ring Closure ◽  
Target Compound ◽  
Metathesis Reaction ◽  
Grubbs Catalyst ◽  
Ring Opening Reaction ◽  
Ultrasound Assisted ◽  
Key Steps

A straightforward chiral pool synthesis for the first fluorinated calystegin is described. Key steps of this synthesis include an ultrasound-assisted Zn-mediated tandem ring opening reaction followed by a Grubbs’ catalyst-mediated ring closure metathesis reaction. The target compound is a selective and competitive inhibitor for a β -glycosidase.

Total Synthesis of Anticancer Agent EBC-23

2016 ◽  
Vol 18 (17) ◽  
pp. 4202-4205 ◽  
Author(s):  
Dodda Vasudeva Reddy ◽  
Gowravaram Sabitha ◽  
Tadikamalla Prabhakar Rao ◽  
Jhillu Singh Yadav
Keyword(s):  
Total Synthesis ◽  
Anticancer Agent

scholarly journals Total Synthesis of Kealiiquinone, an Imidazole Marine Alkaloid.

1997 ◽  
Vol 45 (9) ◽  
pp. 1393-1398 ◽  
Author(s):  
Ikuo KAWASAKI ◽  
Norio TAGUCHI ◽  
Masayuki YAMASHITA ◽  
Shunsaku OHTA
Keyword(s):  
Total Synthesis ◽  
Marine Alkaloid

Total Synthesis of a Marine Alkaloid from the TunicateDendrodoa grossularia

2008 ◽  
Vol 10 (17) ◽  
pp. 3737-3739 ◽  
Author(s):  
Christopher D. Hupp ◽  
Jetze J. Tepe
Keyword(s):  
Total Synthesis ◽  
Marine Alkaloid

ChemInform Abstract: Enantioselective Total Synthesis of the Marine Alkaloid Lepadin B.

ChemInform ◽  
2010 ◽  
Vol 30 (31) ◽  
pp. no-no
Author(s):  
Naoki Toyooka ◽  
Maiko Okumura ◽  
Hiroki Takahata
Keyword(s):  
Total Synthesis ◽  
Enantioselective Total Synthesis ◽  
Marine Alkaloid

A formal total synthesis of the marine alkaloid aaptamine

Tetrahedron ◽  
2008 ◽  
Vol 64 (22) ◽  
pp. 5236-5245 ◽  
Author(s):  
Enrique L. Larghi ◽  
Blaise V. Obrist ◽  
Teodoro S. Kaufman
Keyword(s):  
Total Synthesis ◽  
Marine Alkaloid

Total synthesis of the putative structure of the marine alkaloid haliclorensin

2001 ◽  
Vol 25 (11) ◽  
pp. 1347-1350 ◽  
Author(s):  
Martin G. Banwell ◽  
Andrew M. Bray ◽  
Alison J. Edwards ◽  
David J. Wong
Keyword(s):  
Total Synthesis ◽  
Marine Alkaloid
Sign in / Sign up

Export Citation Format

Share Document