scholarly journals Duodenal Ulcer with Massive Gastrointestinal Hemorrhage as an Initial Manifestation in Multiple Myeloma with Extramedullary Disease: A Case Report

Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 134
Author(s):  
Hao-Tse Chiu ◽  
Po-Huang Chen ◽  
Hao Yen ◽  
Chao-Yang Chen ◽  
Chih-Wei Yang ◽  
...  

Plasma cell neoplasms are characterized by dysregulated proliferation of mature B cells, which can present with either single (solitary plasmacytoma) or systemic (multiple myeloma (MM)) involvement. MM with extramedullary plasmacytoma (EMP) is a rare disease that accounts for approximately 3–5% of all plasmacytomas. EMP with gastrointestinal (GI) system involvement is an even rarer entity, accounting for <1% of MM cases. We present a case of aggressive MM with EMP invading the duodenum, initially presented with massive upper GI hemorrhage and small bowel obstruction. A 67-year-old woman was admitted to our hospital owing to a lack of either gas or feces passage for 3 days. Abdominal distention and vomit with a high coffee ground content were observed for 24 h. The patient’s condition was initially diagnosed as small bowel obstruction, upper gastrointestinal bleeding, severe anemia, acute renal failure, and hypercalcemia. Furthermore, an analysis of immunoelectrophoresis in the blood, bone marrow aspiration, and tissue biopsy supported the diagnosis of MM and EMP invading the duodenum, upper GI hemorrhage, and small bowel obstruction. Our study provided the possible involvement of MM and EMP in the differential diagnosis of patients with unexplained GI hemorrhage and small bowel obstruction. A thorough review of the literature regarding the association between MM, GI hemorrhage, and small bowel obstruction is presented in this study.

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Aubrey A. Mwinyogle ◽  
Astha Bhatt ◽  
Katarina Kapisoda ◽  
Justin Somerville ◽  
Steven C. Cunningham

2016 ◽  
Vol 50 (1) ◽  
pp. e25-e27
Author(s):  
Harika Tirumani ◽  
Sree Harsha Tirumani ◽  
Nikhil H. Ramaiya ◽  
Nikhil C. Munshi

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Khuram Khan ◽  
Saqib Saeed ◽  
Haytham Maria ◽  
Mohammed Sbeih ◽  
Farhana Iqbal ◽  
...  

Introduction. Duodenal diverticulum is a rare disease that can be easily missed. The incidence of duodenal diverticulum diagnosed by upper GI study is approximately 5%. Autopsy results show that 22% of the population have duodenum diverticulum. Most patients with duodenal diverticulum are asymptomatic. However, complications like inflammation, perforation with retroperitoneal abscess, sepsis, pancreatitis, bile duct obstruction, and bleeding can occur. Approximately 162 cases of perforated duodenal diverticulum have been reported in the literature. Case Presentation. We present a rare case of an 82-year-old female with perforation of a duodenal diverticulum caused by small bowel obstruction; in addition to this, there was a synchronous colonic tumor. Conclusion. Diagnosis and management of this rare disorder are controversial. Nonoperative management is advocated in some cases. Some of the cases require early aggressive surgical intervention. The mortality rate remains approximately 45% in all these patients.


2014 ◽  
Vol 4 (1) ◽  
pp. 36-39
Author(s):  
Kalpana Sharma

ABSTRACT Metastatic involvement of small intestine from a head and neck primary is a rare occurrence and carries an unfavourable prognosis. Small bowel metastases usually present with obstruction, perforation or bleeding. Small bowel obstruction due to a metastatic stricture is uncommon and mostly occurs as part of generalized carcinomatosis. Rarely, it selectively affects in the form of a solitary malignant stricture. We report the first case in medical literature of a patient presenting with small bowel obstruction due to a solitary malignant jejunal stricture caused by metastasis from a primary squamous cell carcinoma of the pyriform fossa, four years after the primary tumor was diagnosed and treated with radiotherapy. To the best of our knowledge, there are no reports of primary tumors of hypopharynx metastasizing to jejunum and presenting antemortem. The rarity of intestinal obstruction as an initial manifestation of metastatic dissemination of a hypopharyngeal malignancy as well as its poor prognosis has been discussed. How to cite this article Sharma K. Solitary Jejunal Metastasis from Carcinoma Pyriform Fossa presenting as Intestinal Obstruction. Int J Phonosurg Laryngol 2014;4(1):36-39.


2015 ◽  
Vol 88 (3) ◽  
pp. 330
Author(s):  
Myung-Won Lee ◽  
Ji-Young Moon ◽  
Hea-Won Rhu ◽  
Yoon-Seok Choi ◽  
Ik-Chan Song ◽  
...  

2007 ◽  
Vol 57 (6) ◽  
pp. 571
Author(s):  
Young Cheol Lee ◽  
Young Tong Kim ◽  
Won Kyung Bae ◽  
Il Young Kim

2019 ◽  
Vol 8 (2) ◽  
Author(s):  
David Muchuweti ◽  
Hopewell Mungani ◽  
Hopewell Mungani ◽  
Farai Mahomva ◽  
Edwin Gamba Muguti ◽  
...  

Oftentimes general surgeons working in poorly resourced communities carry out emergency abdominal surgery in patients with acute abdomen with no definitive preoperative diagnosis. The definitive diagnosis is made at laparotomy. Perforated small bowel obstruction secondary to heavy Infestation with Ascaris Lumbricoides brings a number of intraoperative challenges requiring correct intraoperative surgical management decisions. We present a case of a 17 year-old patient who was admitted with a diagnosis of small bowel obstruction who at laparotomy was found to have perforated gangrenous small bowel volvulus with heavy worm load visible through the bowel wall. Because of faecal peritoneal contamination and haemodynamic instability she underwent a two staged procedure with good outcome.


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