scholarly journals Association between Daily Urinary Sodium Excretion, Ratio of Extracellular Water-to-Total Body Water Ratio, and Kidney Outcome in Patients with Chronic Kidney Disease

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 650
Author(s):  
Kaori Kohatsu ◽  
Sayaka Shimizu ◽  
Yugo Shibagaki ◽  
Tsutomu Sakurada

Whether dietary salt intake affects chronic kidney disease (CKD) progression remains unclear. We conducted a retrospective cohort study to analyze the effects of both daily salt intake (DSI) and volume status on renal outcomes in 197 CKD patients. DSI was estimated by 24-h urinary sodium excretion and volume status was assessed by the ratio of extracellular water (ECW) to total body water (TBW) measured by bioelectrical impedance analysis (BIA). We divided patients into two groups according to DSI (6 g/day) or median ECW/TBW (0.475) and compared renal outcomes of each group. Furthermore, we classified and analyzed four groups according to both DSI and ECW/TBW. The higher DSI group showed a 1.69-fold (95% confidence interval (CI) 1.12–2.57, p = 0.01) excess risk of outcome occurrence compared to the lower group. Among the four groups, compared with Group 1 (low DSI and low ECW/TBW), Group 3 (high DSI and low ECW/TBW) showed a 1.84-fold (95% CI 1.03–3.30, p = 0.04) excess risk of outcome occurrence; however, Group 2 (low DSI and high ECW/TBW) showed no significant difference. High salt intake appears to be associated with poor renal outcome independent of blood pressure (BP), proteinuria, and volume status.

2015 ◽  
Vol 40 (1) ◽  
pp. 59-65 ◽  
Author(s):  
Andrea E.C. Hallvass ◽  
Lígia Maria Claro ◽  
Simone Gonçalves ◽  
Márcia Olandoski ◽  
Fabiana Baggio Nerbass ◽  
...  

The purpose of this study was to estimate sodium intake in a group of patients with chronic kidney disease (CKD) and to correlate the results with the urinary excretion values of sodium and signs of fluid overload. We included patients with CKD in different stages. Urinary sodium was measured in 24 h urine samples. Body composition monitor (BCM) was used to estimate the hydration status. Sixty patients (38 ± 15 ml/min of GFR) presented 4.14 ± 1.71 g/24 h of urinary sodium excretion. Overhydration was detected in 50% of the patients by the BCM. There was a positive correlation between the measured sodium excretion values and BCM, ICW, ECW and TBW. In conclusion, markers of overhydration evaluated by BCM were positively correlated with urinary sodium excretion.


2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i559-i560
Author(s):  
Anastasia Markaki ◽  
Periklis kyriazis ◽  
Athanasios Rizos ◽  
Vasilis Zafiropulos ◽  
Stamatia Skoulikidi ◽  
...  

2013 ◽  
Vol 28 (6) ◽  
pp. 1526-1532 ◽  
Author(s):  
Emily P. McQuarrie ◽  
Ellen Marie Freel ◽  
Patrick B. Mark ◽  
Robert Fraser ◽  
John M.C. Connell ◽  
...  

2014 ◽  
Vol 86 (3) ◽  
pp. 582-588 ◽  
Author(s):  
Li Fan ◽  
Hocine Tighiouart ◽  
Andrew S. Levey ◽  
Gerald J. Beck ◽  
Mark J. Sarnak

Nephron ◽  
2019 ◽  
Vol 143 (4) ◽  
pp. 255-263
Author(s):  
Bruna De Vico Ribeiro ◽  
Fabiana Baggio Nerbass ◽  
Andrea Emanuela Chaud Hallvass ◽  
Roberto Pecoits-Filho ◽  
Lilian Cuppari

Sign in / Sign up

Export Citation Format

Share Document