Faculty Opinions recommendation of Analysis of translesion replication across an abasic site by DNA polymerase IV of Escherichia coli.

2003 ◽  
Author(s):  
Errol C Friedberg
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
Abasic Site ◽  
Dna Polymerase Iv

Analysis of translesion replication across an abasic site by DNA polymerase IV of Escherichia coli

DNA Repair ◽  
2003 ◽  
Vol 2 (11) ◽  
pp. 1227-1238 ◽  
Author(s):  
Ayelet Maor-Shoshani ◽  
Ken Hayashi ◽  
Haruo Ohmori ◽  
Zvi Livneh
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
Abasic Site ◽  
Dna Polymerase Iv

scholarly journals Error-prone bypass of certain DNA lesions by the human DNA polymerase κ

2000 ◽  
Vol 14 (13) ◽  
pp. 1589-1594 ◽  
Author(s):  
Eiji Ohashi ◽  
Tomoo Ogi ◽  
Rika Kusumoto ◽  
Shigenori Iwai ◽  
Chikahide Masutani ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
High Frequency ◽  
Dna Lesions ◽  
Human Homolog ◽  
Abasic Site ◽  
Thymine Dimer ◽  
Human Dna

The Escherichia coli protein DinB is a newly identified error-prone DNA polymerase. Recently, a human homolog of DinB was identified and named DINB1. We report that the DINB1gene encodes a DNA polymerase (designated polκ), which incorporates mismatched bases on a nondamaged template with a high frequency. Moreover, polκ bypasses an abasic site andN-2–acetylaminofluorene (AAF)-adduct in an error-prone manner but does not bypass a cis–syn or (6-4) thymine–thymine dimer or a cisplatin-adduct. Therefore, our results implicate an important role for polκ in the mutagenic bypass of certain types of DNA lesions.

scholarly journals Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

1999 ◽  
Vol 96 (21) ◽  
pp. 11922-11927 ◽  
Author(s):  
V. L. Gerlach ◽  
L. Aravind ◽  
G. Gotway ◽  
R. A. Schultz ◽  
E. V. Koonin ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
Dna Polymerase Iv ◽  
Human And Mouse

scholarly journals A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli

2013 ◽  
Vol 41 (9) ◽  
pp. 5104-5114 ◽  
Author(s):  
Amit Sharma ◽  
Jithesh Kottur ◽  
Naveen Narayanan ◽  
Deepak T. Nair
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
Serine Residue ◽  
Mutator Activity ◽  
Dna Polymerase Iv

scholarly journals Discrimination against the Fluorescent Cytosine Analog tC by Escherichia coli DNA Polymerase IV DinB

2011 ◽  
Vol 25 (S1) ◽  
Author(s):  
Jason Walsh ◽  
Imenne Bouamaied ◽  
Tom Brown ◽  
Marcus Wilhelmsson ◽  
Penny J Beuning
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
Dna Polymerase Iv
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