Faculty Opinions recommendation of Actin cytoskeleton as the principal determinant of size-dependent DNA mobility in cytoplasm: a new barrier for non-viral gene delivery.

2005 ◽  
Author(s):  
Yu-Li Wang
Keyword(s):  
Gene Delivery ◽  
Actin Cytoskeleton ◽  
Viral Gene ◽  
Size Dependent ◽  
Dna Mobility ◽  
Viral Gene Delivery

Recent advances in the analysis full/empty capsid ratio and genome integrity of adeno-associated virus (AAV) gene delivery vectors

2020 ◽  
Vol 20 ◽  
Author(s):  
L. Hajba ◽  
A. Guttman
Keyword(s):  
Gene Delivery ◽  
High Efficiency ◽  
Analytical Techniques ◽  
Viral Gene ◽  
Adeno Associated Virus ◽  
Gene Delivery Vectors ◽  
Empty Capsid ◽  
Purification Methods ◽  
Viral Gene Delivery

: Adeno-associated virus (AAV) is one of the most promising viral gene delivery vectors with long-term gene expression and disease correction featuring high efficiency and excellent safety in human clinical trials. During the production of AAV vectors,there are several quality control (QC)parameters that should be rigorously monitored to comply with clini-cal safety and efficacy. This review gives a short summary of the most frequently used AVV production and purification methods,focusing on the analytical techniques applied to determine the full/empty capsid ratio and the integrity of the encapsidated therapeutic DNA of the products.

Non-viral gene delivery to atelectatic and ventilated lungs

2002 ◽  
Vol 73 (2) ◽  
pp. 432-437 ◽  
Author(s):  
Uz Stammberger ◽  
Aima N. Uduehi ◽  
Bartosz Kubisa ◽  
Thierry Roth ◽  
Ralph A. Schmid
Keyword(s):  
Gene Delivery ◽  
Viral Gene ◽  
Viral Gene Delivery

Modulating polymer chemistry to enhance non-viral gene delivery inside hydrogels with tunable matrix stiffness

Biomaterials ◽  
2013 ◽  
Vol 34 (37) ◽  
pp. 9657-9665 ◽  
Author(s):  
Michael Keeney ◽  
Sheila Onyiah ◽  
Zhe Zhang ◽  
Xinming Tong ◽  
Li-Hsin Han ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Polymer Chemistry ◽  
Viral Gene ◽  
Matrix Stiffness ◽  
Viral Gene Delivery

scholarly journals Non-viral gene delivery nanoparticles based on Poly(β-amino esters) for treatment of glioblastoma

Biomaterials ◽  
2011 ◽  
Vol 32 (23) ◽  
pp. 5402-5410 ◽  
Author(s):  
Stephany Y. Tzeng ◽  
Hugo Guerrero-Cázares ◽  
Elliott E. Martinez ◽  
Joel C. Sunshine ◽  
Alfredo Quiñones-Hinojosa ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Viral Gene ◽  
Amino Esters ◽  
Viral Gene Delivery

Non-Viral Gene Delivery Methods

2013 ◽  
Vol 14 (1) ◽  
pp. 46-60 ◽  
Author(s):  
Weiwei Wang ◽  
Wenzhong Li ◽  
Nan Ma ◽  
Gustav Steinhoff
Keyword(s):  
Gene Delivery ◽  
Viral Gene ◽  
Delivery Methods ◽  
Viral Gene Delivery

scholarly journals Delivery of Condensed DNA by Liposomal Non-viral Gene Delivery System into Nucleus of Dendritic Cells

2006 ◽  
Vol 29 (6) ◽  
pp. 1290-1293 ◽  
Author(s):  
Takashi Nakamura ◽  
Rumiko Moriguchi ◽  
Kentaro Kogure ◽  
Arisa Minoura ◽  
Tomoya Masuda ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Gene Delivery ◽  
Delivery System ◽  
Viral Gene ◽  
Gene Delivery System ◽  
Viral Gene Delivery ◽  
Condensed Dna
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