Faculty Opinions recommendation of Effect of different components of triple-H therapy on cerebral perfusion in patients with aneurysmal subarachnoid haemorrhage: a systematic review.

Objective This systematic review aimed to define the relationship between diabetes mellitus (DM) and the risk of aneurysmal subarachnoid haemorrhage (aSAH). Methods Studies associated with DM and aSAH published until March 2016 were retrieved from Pubmed, Embase, Web of Science, and Cochrane Library databases. A random-effects model was used to calculate the relative risks (RRs) with 95% confidence intervals (CIs). Results Eighteen observational studies were retrieved. The overall RRs for DM and aSAH were RRs = 0.59 (0.44, 0.79), with moderate heterogeneity ( I2 = 55.7%, Pheterogeneity = 0.000). Subgroup analysis by study quality revealed a reduced association between DM and aSAH risk in high quality studies only (RRs = 0.40, 95% CI: 0.29, 0.56; I2 = 0.0%, Pheterogeneity = 0.549), therefore study quality may be a source of heterogeneity. Conclusion A potential decreased risk of aSAH in DM patients was found in high quality studies. Further studies are required to confirm this causal relationship and to investigate the biological mechanisms.

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Delayed cerebral ischaemia prevention and treatment after aneurysmal subarachnoid haemorrhage: a systematic review

British Journal of Anaesthesia ◽

10.1093/bja/aew095 ◽

2016 ◽

Vol 117 (1) ◽

pp. 17-40 ◽

Cited By ~ 25

Author(s):

M. Veldeman ◽

A. Höllig ◽

H. Clusmann ◽

A. Stevanovic ◽

R. Rossaint ◽

...

Keyword(s):

Systematic Review ◽

Subarachnoid Haemorrhage ◽

Cerebral Ischaemia ◽

Aneurysmal Subarachnoid Haemorrhage ◽

Delayed Cerebral Ischaemia ◽

Prevention And Treatment

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Treatment of cerebral vasospasm following aneurysmal subarachnoid haemorrhage: a systematic review and meta-analysis

European Radiology ◽

10.1007/s00330-016-4702-y ◽

2016 ◽

Vol 27 (8) ◽

pp. 3333-3342 ◽

Cited By ~ 28

Author(s):

Grégoire Boulouis ◽

Marc Antoine Labeyrie ◽

Jean Raymond ◽

Christine Rodriguez-Régent ◽

Anne Claire Lukaszewicz ◽

...

Keyword(s):

Systematic Review ◽

Subarachnoid Haemorrhage ◽

Cerebral Vasospasm ◽

Meta Analysis ◽

Aneurysmal Subarachnoid Haemorrhage

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Sentinel Headaches in Aneurysmal Subarachnoid Haemorrhage: What is the True Incidence? A Systematic Review

Cephalalgia ◽

10.1046/j.1468-2982.2003.00596.x ◽

2003 ◽

Vol 23 (10) ◽

pp. 935-941 ◽

Cited By ~ 93

Author(s):

A Polmear

Keyword(s):

Systematic Review ◽

Subarachnoid Haemorrhage ◽

Case Control ◽

Aneurysmal Subarachnoid Haemorrhage ◽

Recall Bias ◽

Case Control Studies ◽

True Incidence ◽

Number Of Patients ◽

History Of ◽

Real Entity

The aim of this systematic review was to determine the incidence of sentinel headache reported by patients with aneurysmal subarachnoid haemorrhage, and whether they are likely to be due to recall bias or to misdiagnosis of a previous haemorrhage. Nine studies of good quality, which reported the number of patients with aneurysmal subarachnoid haemorrhage with a history of sentinel headache, gave rates of 10% to 43%. Two case-control studies, in which the frequency of a history of sentinel headache in patients with aneurysmal subarachnoid haemorrhage was compared with that in controls with non-aneurysmal subarachnoid haemorrhage or with stroke, gave an incidence of 5% (95% confidence interval 0.5, 16) in controls, suggesting that only a small number of apparent sentinel headaches are due to recall bias. Sentinel headaches appear to be a real entity. Their true incidence may vary from near zero to about 40% according to the rate of misdiagnosis in the community under consideration.

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