Faculty Opinions recommendation of An efficient approach to the discovery of potent inhibitors against glycosyltransferases.

Author(s):  
Thomas W von Geldern
Keyword(s):  
AIAA Journal ◽  
1998 ◽  
Vol 36 ◽  
pp. 2005-2012
Author(s):  
L. He ◽  
W. Ning

2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>


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