Faculty Opinions recommendation of Sexual transmission of hepatitis C virus among monogamous heterosexual couples: the HCV partners study.

Background: Hepatitis C virus (HCV) is now recognized as the cause of 90% of non-A, non-B (NANB) hepatitis. This virus is responsible for a large percentage of chronic persistent and chronic active hepatitis in the United States. Parenteral and sexual transmission are well described, so a significant population of pregnant patients is at risk. Vertical transmission of the virus to the fetus is dependent upon the level of maternal viremia.Case: The cases described in the following report demonstrate that fulminant disease may present in pregnancy. They also demonstrate the cofactors promoting the severity of illness, methods of diagnosis, potential treatment, and outcome of the infection.Conclusion: HCV may be encountered in pregnancy. Although most acute-phase illness will be self limiting, some patients will manifest liver failure during gestation. Because vertical transmission to the fetus is possible, the pediatrician should be informed of the maternal disease. Chronic hepatitis is almost the rule rather than the exception, so patients require close postpartum follow-up. Interferon, which may alter the course of the chronic disease, has been used on rare occasions in pregnancy.

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Sexual Transmission of Hepatitis C Virus Among Female Sex Workers in India

International Journal of Infectious Diseases ◽

10.1016/j.ijid.2008.05.1096 ◽

2008 ◽

Vol 12 ◽

pp. e416-e417 ◽

Cited By ~ 1

Author(s):

P. Barua ◽

N. Laskar ◽

G.K. Medhi ◽

B. Apum ◽

J. Mahanta

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Sex Workers ◽

Female Sex Workers ◽

Sexual Transmission ◽

Female Sex

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Sexual transmission of hepatitis C virus

Haemophilia ◽

10.1111/j.1365-2516.1995.tb00126.x ◽

1995 ◽

Vol 1 (S4) ◽

pp. 15-18 ◽

Cited By ~ 2

Author(s):

P. TELFER

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Sexual Transmission

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Parenteral and Sexual Transmission of GB Virus C and Hepatitis C Virus among Human Immunodeficiency Virus‐Positive Patients

The Journal of Infectious Diseases ◽

10.1086/517488 ◽

1997 ◽

Vol 175 (4) ◽

pp. 1025-1026 ◽

Cited By ~ 1

Author(s):

Gianfranco Fiordalisi ◽

Alessandra Bettinardi ◽

Isabella Zanella ◽

Roberto Stellini ◽

Giuseppe Paraninfo ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Sexual Transmission ◽

Gb Virus C ◽

Immunodeficiency Virus ◽

Virus C

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Presence and Predictors of Hepatitis C Virus RNA in the Semen of Homeless Men

Biological Research For Nursing ◽

10.1177/1099800402004001004 ◽

2002 ◽

Vol 4 (1) ◽

pp. 22-30 ◽

Cited By ~ 26

Author(s):

Adeline Nyamathi ◽

Wendie A. Robbins ◽

John L. Fahey ◽

Dorothy Wiley ◽

Vyacheslav A. Pekler ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Sexual Transmission ◽

Hcv Rna ◽

Behavioral Risk ◽

Methamphetamine Use ◽

Viral Loads ◽

Homeless Men ◽

Virus Rna ◽

Increase Risk

Although the possibility of sexual transmission of the hepatitis C virus (HCV) remains controversial, little is known of the associations of positive semen specimens with potential demographic and behavioral risk factors. Knowledge of these predictors may suggest factors that increase risk of HCV RNA in the semen. Semen and blood from 80 HCV-infected homeless men were evaluated for the presence ofHCVRNA by means of branch DNA and transcription-mediated amplification analyses. Associations of selected demographic and behavioral characteristics of the participants with presence or absence of HCV in their semen were also assessed. HCV RNA was detected in the semen of 36% of the sample. Associations were found with HCV RNA in semen and older age, higher viral loads of HCV in blood, current alcohol and lifetime methamphetamine use, and having been vaccinated for the hepatitis B virus. Findings suggest that sexual transmission of HCV is plausible and shed light on the need to conduct more in-depth investigations.

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