Faculty Opinions recommendation of Towards practical, high-capacity, low-maintenance information storage in synthesized DNA.

Author(s):  
Nicola Mulder
2021 ◽  
Author(s):  
Lin Lu ◽  
Kaojin Wang ◽  
Haozhong Wu ◽  
Anjun Qin ◽  
Ben Zhong Tang

With the advent of the big data era, information storage and security are becoming increasingly important. However, high capacity information storage and multilevel anti-counterfeiting are typically difficult to simultaneously achieve....


2021 ◽  
Author(s):  
Lin Lu ◽  
Kaojin Wang ◽  
Haozhong Wu ◽  
Anjun Qin ◽  
Ben Zhong Tang

With the advent of the big data era, information storage and security are becoming increasingly important. However, high capacity information storage and multilevel anti-counterfeiting are typically difficult to simultaneously achieve. To address this challenge, herein, two electrochromic and electrofluorochromic dual-functional polymers with aggregation-induced emission (AIE) features are skillfully designed. Upon application of voltage, the absorption and fluorescence spectra of the two polymers can undergo reversible changes, accompanying with the variation of appearance color and emission. By utilizing the controllable characteristics of polymers, the dual-mode display devices are fabricated via a simple spraying method. More interestingly, the color code device was elaborately constructed by adding color change multiplexing to two-dimensional space, thereby achieving high capacity information storage. Moreover, the color code device can also be applied in the multilevel anti-counterfeiting areas. The encrypted information can be dynamically converted under different voltages. The AIE polymers show great promise in the applications of multidimensional information storage and dynamic anti-counterfeiting and the design strategy may provide a new path for advanced information storage and high security technology.<br><div><br></div>


Nature ◽  
2013 ◽  
Vol 494 (7435) ◽  
pp. 77-80 ◽  
Author(s):  
Nick Goldman ◽  
Paul Bertone ◽  
Siyuan Chen ◽  
Christophe Dessimoz ◽  
Emily M. LeProust ◽  
...  

2022 ◽  
Vol 4 (1) ◽  
Author(s):  
Alex El-Shaikh ◽  
Marius Welzel ◽  
Dominik Heider ◽  
Bernhard Seeger

ABSTRACT Due to the rapid cost decline of synthesizing and sequencing deoxyribonucleic acid (DNA), high information density, and its durability of up to centuries, utilizing DNA as an information storage medium has received the attention of many scientists. State-of-the-art DNA storage systems exploit the high capacity of DNA and enable random access (predominantly random reads) by primers, which serve as unique identifiers for directly accessing data. However, primers come with a significant limitation regarding the maximum available number per DNA library. The number of different primers within a library is typically very small (e.g. ≈10). We propose a method to overcome this deficiency and present a general-purpose technique for addressing and directly accessing thousands to potentially millions of different data objects within the same DNA pool. Our approach utilizes a fountain code, sophisticated probe design, and microarray technologies. A key component is locality-sensitive hashing, making checks for dissimilarity among such a large number of probes and data objects feasible.


2021 ◽  
Author(s):  
Lin Lu ◽  
Kaojin Wang ◽  
Haozhong Wu ◽  
Anjun Qin ◽  
Ben Zhong Tang

With the advent of the big data era, information storage and security are becoming increasingly important. However, high capacity information storage and multilevel anti-counterfeiting are typically difficult to simultaneously achieve. To address this challenge, herein, two electrochromic and electrofluorochromic dual-functional polymers with aggregation-induced emission (AIE) features are skillfully designed. Upon application of voltage, the absorption and fluorescence spectra of the two polymers can undergo reversible changes, accompanying with the variation of appearance color and emission. By utilizing the controllable characteristics of polymers, the dual-mode display devices are fabricated via a simple spraying method. More interestingly, the color code device was elaborately constructed by adding color change multiplexing to two-dimensional space, thereby achieving high capacity information storage. Moreover, the color code device can also be applied in the multilevel anti-counterfeiting areas. The encrypted information can be dynamically converted under different voltages. The AIE polymers show great promise in the applications of multidimensional information storage and dynamic anti-counterfeiting and the design strategy may provide a new path for advanced information storage and high security technology.<br><div><br></div>


2018 ◽  
Vol 24 ◽  
pp. 1185-1187 ◽  
Author(s):  
George B. Stefano ◽  
Fuzhou Wang ◽  
Richard M. Kream

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