Faculty Opinions recommendation of Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington's disease models.

2015 ◽  
Author(s):  
John Lowe
Keyword(s):  
Huntington's Disease ◽  
Small Molecules ◽  
Huntington’S Disease ◽  
Disease Models ◽  
Connectivity Mapping

scholarly journals Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington’s disease models

2015 ◽  
Vol 94 (2) ◽  
pp. 235-245 ◽  
Author(s):  
Joshua L. Smalley ◽  
Carlo Breda ◽  
Robert P. Mason ◽  
Gurdeep Kooner ◽  
Ruth Luthi-Carter ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Small Molecules ◽  
Huntington’S Disease ◽  
Disease Models ◽  
Connectivity Mapping

Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models

2013 ◽  
Vol 127 (1) ◽  
pp. 22-35 ◽  
Author(s):  
Paola Conforti ◽  
Chiara Zuccato ◽  
Germano Gaudenzi ◽  
Alessandro Ieraci ◽  
Stefano Camnasio ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Small Molecules ◽  
Huntington’S Disease ◽  
Gene Transcription ◽  
Disease Models ◽  
Neuronal Gene ◽  
Repressor Complex

scholarly journals Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

2007 ◽  
Vol 3 (6) ◽  
pp. 331-338 ◽  
Author(s):  
Sovan Sarkar ◽  
Ethan O Perlstein ◽  
Sara Imarisio ◽  
Sandra Pineau ◽  
Axelle Cordenier ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Small Molecules ◽  
Huntington’S Disease ◽  
Disease Models

scholarly journals ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington’s disease models

2016 ◽  
Vol 11 (1) ◽  
Author(s):  
Mitchell S. Wold ◽  
Junghyun Lim ◽  
Véronik Lachance ◽  
Zhiqiang Deng ◽  
Zhenyu Yue
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Disease Models

scholarly journals Small Molecule Enhancers of Rapamycin-Induced TOR Inhibition Promote Autophagy, Reduce Toxicity in Huntington’s Disease Models and Enhance Killing of Mycobacteria by Macrophages

Autophagy ◽  
2007 ◽  
Vol 3 (6) ◽  
pp. 620-622 ◽  
Author(s):  
R. Andres Floto ◽  
Sovan Sarkar ◽  
Ethan O. Perlstein ◽  
Beate Kampmann ◽  
Stuart L. Schreiber ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Small Molecule ◽  
Disease Models ◽  
Small Molecule Enhancers

scholarly journals Probucol modulates oxidative stress and excitotoxicity in Huntington's disease models in vitro

2012 ◽  
Vol 87 (4-5) ◽  
pp. 397-405 ◽  
Author(s):  
Dirleise Colle ◽  
Juliana M. Hartwig ◽  
Félix A. Antunes Soares ◽  
Marcelo Farina
Keyword(s):  
Oxidative Stress ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Disease Models
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