Faculty Opinions recommendation of Subcutaneous trigeminal nerve field stimulation for refractory trigeminal pain: a cohort analysis.

A 72-year-old female patient is presented, who was diagnosed with herpes zoster along the left ophthalmic branch of the trigeminal nerve with associated cutaneous vesicles. The patient subsequently developed postherpetic neuralgia in the same dermatome, which, after remission, transformed into paroxysmal trigeminal pain. The two different symptom sets, with the former consistent with PHN and the later consistent with trigeminal neuralgia, were unique to our practice and the literature.

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Trigeminal Neuralgia Caused by Venous Compression

Neurosurgery ◽

10.1227/01.neu.0000129552.87291.87 ◽

2004 ◽

Vol 55 (2) ◽

pp. 334-339 ◽

Cited By ~ 72

Author(s):

Toshio Matsushima ◽

Phuong Huynh-Le ◽

Masayuki Miyazono

Keyword(s):

Trigeminal Neuralgia ◽

Trigeminal Nerve ◽

Microvascular Decompression ◽

Complete Relief ◽

Surgical Results ◽

Meckel’S Cave ◽

Trigeminal Pain ◽

Venous Compression ◽

Facial Numbness ◽

Meckel's Cave

Abstract OBJECTIVE: The purpose of this study is to clarify whether venous compression on the trigeminal nerve really causes trigeminal neuralgia or not, and to identify which veins are the offending veins. METHODS: We used microvascular decompression in operations on 121 patients with typical trigeminal neuralgia. We analyzed the intraoperative findings and surgical results in these 121 cases. RESULTS: In 7 of the 121 cases, only the vein was identified as a compressive factor on the trigeminal nerve. In 6 of these 7 cases, single venous compression was found, whereas the remaining case had two offending veins. The transverse pontine vein was most frequently found as the offending vein near Meckel's cave. All patients showed complete relief of trigeminal pain after decompression of the veins, but four of them developed facial numbness after surgery, which tended to be slight and did not require any treatment. CONCLUSION: Our surgical experiences showed that venous compression could cause trigeminal neuralgia by itself and that the transverse pontine vein should be carefully observed because it is most frequently the offending vein.

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Trigeminal Pain and Its Distribution in Different Trigeminal Nerve Branches

Anesthesiology and Pain Medicine ◽

10.5812/aapm.3764 ◽

2012 ◽

Vol 1 (4) ◽

pp. 271-272 ◽

Cited By ~ 2

Author(s):

Maria Nikolaos Piagkou ◽

Maria Piagkou ◽

Panagiotis Skandalakis ◽

Giannoulis Piagkos ◽

Theano Demesticha

Keyword(s):

Trigeminal Nerve ◽

Trigeminal Pain

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Trigeminal Pain and Its Distribution in Different Trigeminal Nerve Branches

Anesthesiology and Pain Medicine ◽

10.5812/anesthpain.3764 ◽

2012 ◽

Vol 1 (4) ◽

pp. 271-272

Author(s):

Maria Nikolaos Piagkou ◽

Panagiotis Skandalakis ◽

Theano Demesticha

Keyword(s):

Trigeminal Nerve ◽

Trigeminal Pain

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Pathological Mechanisms and Therapeutic Targets for Trigeminal Neuropathic Pain

Medicines ◽

10.3390/medicines6030091 ◽

2019 ◽

Vol 6 (3) ◽

pp. 91 ◽

Cited By ~ 4

Author(s):

Bista ◽

Imlach

Keyword(s):

Neuropathic Pain ◽

Trigeminal Nerve ◽

Healthcare Providers ◽

Great Promise ◽

Preclinical Studies ◽

Therapeutic Approaches ◽

Chronic Pain Condition ◽

Trigeminal Neuropathic Pain ◽

Trigeminal Pain ◽

Central Nervous System Dysfunction

Trigeminal neuropathic pain is a chronic pain condition caused by damage or inflammation of the trigeminal nerve or its branches, with both peripheral and central nervous system dysfunction contributing to the disorder. Trigeminal pain conditions present with diagnostic and therapeutic challenges to healthcare providers and often require multiple therapeutic approaches for pain reduction. This review will provide the overview of pathophysiology in peripheral and central nociceptive circuits that are involved in neuropathic pain conditions involving the trigeminal nerve and the current therapeutics that are used to treat these disorders. Recent advances in treatment of trigeminal pain, including novel therapeutics that target ion channels and receptors, gene therapy and monoclonal antibodies that have shown great promise in preclinical studies and clinical trials will also be described.

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