Faculty Opinions recommendation of Patient reported outcome of adult perioperative anaesthesia in the United Kingdom: a cross-sectional observational study.

2018 ◽  
Author(s):  
Luzius A Steiner
Keyword(s):  
United Kingdom ◽  
Observational Study ◽  
Patient Reported Outcome ◽  
Cross Sectional ◽  
The United Kingdom ◽  
Patient Reported

scholarly journals Predicting EQ-5D Index Scores from the PROMIS-29 Profile for the United Kingdom, France, and Germany

2020 ◽  
Author(s):  
Christoph Paul Klapproth ◽  
Jan van Bebber ◽  
Christopher J. Gibbons ◽  
Jose M Valderas ◽  
Leplege Alain ◽  
...  
Keyword(s):  
United Kingdom ◽  
Health Utility ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
Order Effects ◽  
The United Kingdom ◽  
Life Years ◽  
Patient Reported ◽  
Reported Health ◽  
The Uk

Abstract Background: EQ-5D health utility (HU) scores are commonly used in health economics to compute quality-adjusted life years (QALYs). EQ-5D scores, which are country-specific, can be derived directly or by mapping from self-reported health-related quality of life (HRQoL) scales such as the PROMIS-29 profile. The PROMIS-29 from the Patient Reported Outcome Measures Information System is a comprehensive assessment of self-reported health with excellent psychometric properties. We sought to find optimal models for predicting EQ-5D scores from the PROMIS-29 in the United Kingdom, France, and Germany and compared the prediction performances with that of a US model.Methods: We collected EQ-5D-5L and PROMIS-29 profiles and three samples representative of the general populations in the UK (n=1,509), France (n=1,501), and Germany (n=1,502). We used stepwise regression with backward selection to find the best models to predict the EQ-5D score from all seven PROMIS-29 domains. We investigated the agreement between the observed and predicted EQ-5D scores in all three countries using various indices for the prediction performance, including Bland-Altman plots to examine the performance along the HU continuum.Results:The EQ-5D index scores were best predicted in Germany (RMSEGER = 0.10, MAEGER = 0.06), followed by France (RMSEFR = 0.11, MAEFR = 0.08) and the UK (RMSEUK = 0.12, MAEUK = 0.09). The Bland-Altman plots show that the inclusion of higher-order effects reduced the underprediction of low HU scores.Conclusions: Our models provide a valid method to predict EQ-5D-5L index scores from the PROMIS-29 for the UK, France, and Germany.

scholarly journals Prevalence of unmet needs for spasticity management in care home residents in the East Midlands, United Kingdom: a cross-sectional observational study

2019 ◽  
Vol 33 (11) ◽  
pp. 1819-1830 ◽  
Author(s):  
Laura Edwards ◽  
Benjamin Ellis ◽  
Clare Donnellan ◽  
Hanan Osman ◽  
Naseer Haboubi ◽  
...  
Keyword(s):  
United Kingdom ◽  
Observational Study ◽  
Unmet Needs ◽  
Care Home ◽  
Unmet Need ◽  
Passive Movement ◽  
Cross Sectional ◽  
The United Kingdom ◽  
East Midlands

Objective: To establish the prevalence of unmet need for spasticity management in care home residents in two counties of the United Kingdom. Design: Cross-sectional observational study with a six-month follow-up arm for participants with identified unmet needs. Setting: 22 care homes in Derbyshire and Nottinghamshire. Subjects: 60 care home residents with upper motor neuron syndrome–related spasticity. Interventions: No intervention. When unmet needs around spasticity management were identified, the participant’s general practitioner was advised of these in writing. Main measures: Resistance to Passive Movement Scale to assess spasticity; recording of (a) the presence of factors which may aggravate spasticity, (b) potential complications of spasticity, (c) spasticity-related needs and (d) current interventions to manage spasticity. Two assessors judged the presence or absence of needs for spasticity management and whether these needs were met by current care. Results: Out of 60 participants, 14 had no spasticity-related needs; 46 had spasticity-related needs; 11 had needs which were being met by current care and 35 participants had spasticity-related needs at baseline which were not being met by their current care. These were most frequently related to the risk of contracture development or problems with skin hygiene or integrity in the upper limb. In total, 6 participants had one or more pressure sores and 35 participants had one or more established joint contractures. A total of 31 participants were available for follow-up. Informing general practitioners of unmet needs resulted in no change to spasticity management in 23/31 cases. Conclusion: Care home residents in this study had high levels of unmet need for spasticity management.

scholarly journals Predicting EQ-5D-3L index value from the PROMIS-29 profile for the United Kingdom, France, and Germany

2020 ◽  
Author(s):  
Christoph Paul Klapproth ◽  
Jan van Bebber ◽  
Christopher J. Sidey-Gibbons ◽  
Jose M Valderas ◽  
Alain Leplege ◽  
...  
Keyword(s):  
United Kingdom ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
Order Effects ◽  
Health State ◽  
The United Kingdom ◽  
Life Years ◽  
Patient Reported ◽  
Reported Health ◽  
The Uk

Abstract Background: EQ-5D health state utilities (HSU) are commonly used in health economics to compute quality-adjusted life years (QALYs). The EQ-5D, which is country-specific, can be derived directly or by mapping from self-reported health-related quality of life (HRQoL) scales such as the PROMIS-29 profile. The PROMIS-29 from the Patient Reported Outcome Measures Information System is a comprehensive assessment of self-reported health with excellent psychometric properties. We sought to find optimal models predicting the EQ-5D from the PROMIS-29 in the United Kingdom, France, and Germany and compared the prediction performances with that of a US model.Methods: We collected EQ-5D-5L and PROMIS-29 profiles and three samples representative of the general populations in the UK (n=1,509), France (n=1,501), and Germany (n=1,502). We used stepwise regression with backward selection to find the best models to predict the EQ-5D from all seven PROMIS-29 domains. We investigated the agreement between the observed and predicted EQ-5D in all three countries using various indices for the prediction performance, including Bland-Altman plots to examine the performance along the HSU continuum.Results: The EQ-5D was best predicted in France (nRMSEFRA = 0.075, nMAEFRA = 0.052), followed by the UK (nRMSEUK = 0.076, nMAEUK = 0.053) and Germany (nRMSEGER = 0.079, nMAEGER = 0.051). The Bland-Altman plots show that the inclusion of higher-order effects reduced the overprediction of low HSU scores.Conclusions: Our models provide a valid method to predict the EQ-5D from the PROMIS-29 for the UK, France, and Germany.

scholarly journals A cross sectional analysis of a case-control study about quality of life in CRS in the UK; a comparison between CRS subtypes

2016 ◽  
Vol 54 (4) ◽  
pp. 311-315
Author(s):  
S. Erskine ◽  
C. Hopkins ◽  
N. Kumar ◽  
J. Wilson ◽  
A. Clark ◽  
...  
Keyword(s):  
Nasal Polyps ◽  
Patient Reported Outcome ◽  
Cross Sectional ◽  
The United Kingdom ◽  
Patient Reported ◽  
Before And After ◽  
Sinonasal Outcome Test ◽  
The Uk ◽  
Sectional Analysis ◽  
Snot 22

Background: The Sinonasal Outcome Test (SNOT-22) has been used as a patient reported outcome measure to grade symptom severity before and after treatment for chronic rhinosinusitis (CRS). Methodology: This analysis uses data from the CRS Epidemiology Study (CRES). The overarching aim of CRES was to determine factors that influence the onset and severity of CRS. A study-specific questionnaire including SNOT-22 was distributed to patients with CRS attending ENT clinics across 30 centres in the United Kingdom. The aim of this analysis was to compare SNOT-22 scores between those with different types of CRS to determine any differences present in the total score or the subdomains and to assess whether any differences varied according to gender. Results: There were a total of 1249 CRS participants in the following subgroups: CRS without nasal polyps (CRSsNPs) (n=553), CRS with nasal polyps (CRSwNPs) (n=651), allergic fungal rhinosinusitis (AFRS) (n=45). Since there were differing gender ratios in each subgroup, males and females were analysed separately. The mean and standard deviation for SNOT-22 was: males CRSsNP 41.1 (21.0), CRSwNP 41.7 (20.5); females CRSsNP 49.6 (19.7), CRSwNP 49.5 (22.9). In the nasal domain, those with CRSwNP scored more highly than those with CRSsNP; for males 18.1 (8.1) vs. 15.9 (7.9); for females 19.6 (8.0) vs 16.7 (7.5). Conclusions: Patients with CRSwNPs report higher symptom scores in the nasal domain of SNOT-22 than those with CRSsNPs with women in both subgroups reporting higher total scores than men.

scholarly journals Predicting EQ-5D-5L crosswalk from the PROMIS-29 profile for the United Kingdom, France, and Germany

2020 ◽  
Author(s):  
Christoph Paul Klapproth ◽  
Jan van Bebber ◽  
Christopher J. Sidey-Gibbons ◽  
Jose M Valderas ◽  
Alain Leplege ◽  
...  
Keyword(s):  
United Kingdom ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
Order Effects ◽  
Health State ◽  
The United Kingdom ◽  
Life Years ◽  
Patient Reported ◽  
Reported Health ◽  
The Uk

Abstract Background: EQ-5D health state utilities (HSU) are commonly used in health economics to compute quality-adjusted life years (QALYs). The EQ-5D, which is country-specific, can be derived directly or by mapping from self-reported health-related quality of life (HRQoL) scales such as the PROMIS-29 profile. The PROMIS-29 from the Patient Reported Outcome Measures Information System is a comprehensive assessment of self-reported health with excellent psychometric properties. We sought to find optimal models predicting the EQ-5D-5L crosswalk from the PROMIS-29 in the United Kingdom, France, and Germany and compared the prediction performances with that of a US model.Methods: We collected EQ-5D-5L and PROMIS-29 profiles and three samples representative of the general populations in the UK (n=1,509), France (n=1,501), and Germany (n=1,502). We used stepwise regression with backward selection to find the best models to predict the EQ-5D-5L crosswalk from all seven PROMIS-29 domains. We investigated the agreement between the observed and predicted EQ-5D-5L crosswalk in all three countries using various indices for the prediction performance, including Bland-Altman plots to examine the performance along the HSU continuum.Results: The EQ-5D-5L crosswalk was best predicted in France (nRMSEFRA = 0.075, nMAEFRA = 0.052), followed by the UK (nRMSEUK = 0.076, nMAEUK = 0.053) and Germany (nRMSEGER = 0.079, nMAEGER = 0.051). The Bland-Altman plots show that the inclusion of higher-order effects reduced the overprediction of low HSU scores.Conclusions: Our models provide a valid method to predict the EQ-5D-5L crosswalk from the PROMIS-29 for the UK, France, and Germany.

scholarly journals Predicting EQ-5D-5L crosswalk from the PROMIS-29 profile for the United Kingdom, France, and Germany

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Christoph Paul Klapproth ◽  
J. van Bebber ◽  
C. J. Sidey-Gibbons ◽  
J. M. Valderas ◽  
A. Leplege ◽  
...  
Keyword(s):  
United Kingdom ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
Order Effects ◽  
Health State ◽  
The United Kingdom ◽  
Life Years ◽  
Patient Reported ◽  
Reported Health ◽  
The Uk

Abstract Background EQ-5D health state utilities (HSU) are commonly used in health economics to compute quality-adjusted life years (QALYs). The EQ-5D, which is country-specific, can be derived directly or by mapping from self-reported health-related quality of life (HRQoL) scales such as the PROMIS-29 profile. The PROMIS-29 from the Patient Reported Outcome Measures Information System is a comprehensive assessment of self-reported health with excellent psychometric properties. We sought to find optimal models predicting the EQ-5D-5L crosswalk from the PROMIS-29 in the United Kingdom, France, and Germany and compared the prediction performances with that of a US model. Methods We collected EQ-5D-5L and PROMIS-29 profiles and three samples representative of the general populations in the UK (n = 1509), France (n = 1501), and Germany (n = 1502). We used stepwise regression with backward selection to find the best models to predict the EQ-5D-5L crosswalk from all seven PROMIS-29 domains. We investigated the agreement between the observed and predicted EQ-5D-5L crosswalk in all three countries using various indices for the prediction performance, including Bland–Altman plots to examine the performance along the HSU continuum. Results The EQ-5D-5L crosswalk was best predicted in France (nRMSEFRA = 0.075, nMAEFRA = 0.052), followed by the UK (nRMSEUK = 0.076, nMAEUK = 0.053) and Germany (nRMSEGER = 0.079, nMAEGER = 0.051). The Bland–Altman plots show that the inclusion of higher-order effects reduced the overprediction of low HSU scores. Conclusions Our models provide a valid method to predict the EQ-5D-5L crosswalk from the PROMIS-29 for the UK, France, and Germany.

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