scholarly journals Dr. Jean-Pierre Estèbe

2021 ◽  
Vol 25 (2) ◽  
Author(s):  
Dr. Xavier Falieres
Keyword(s):  
Intensive Care ◽  
Regional Anesthesia ◽  
Local Anesthetics ◽  
Medical Studies ◽  
Fundamental Research

It is with great sadness that we heard of the death of Dr Jean-Pierre Estèbe, French anesthesiologist, on the 16th of March 2021. Jean-Pierre Estèbe was born in 1955. He started his medical studies in Rennes, France in 1975 and continued with training in anesthesia-intensive care, primarily wanting to become an intensivist. He was passionate about his job, spending his energy on two fronts: pain and loco-regional anesthesia, problems within and the relevant fundamental research; more specifically the prolongation of analgesia with local anesthetics, which were finalized by a university thesis in 2001.

scholarly journals Direct Cytotoxic and Indirect, Immune-Mediated Effects of Local Anesthetics Against Cancer

2022 ◽  
Vol 11 ◽  
Author(s):  
Alejandra Wu Chuang ◽  
Oliver Kepp ◽  
Guido Kroemer ◽  
Lucillia Bezu
Keyword(s):  
Local Anesthetics ◽  
Oncological Surgery ◽  
Residual Cancer ◽  
Term Survival ◽  
Cytotoxic Effects ◽  
Mediated Effects ◽  
Anticancer Effects ◽  
Immune Mediated ◽  
Fundamental Research

Local anesthetics are frequently employed during surgery in order to control peri- and postoperative pain. Retrospective studies have revealed an unexpected correlation between increased long-term survival and the use of local anesthetics during oncological surgery. This effect of local anesthetics might rely on direct cytotoxic effects on malignant cells or on indirect, immune-mediated effects. It is tempting to speculate, yet needs to be formally proven, that the combination of local anesthetics with oncological surgery and conventional anticancer therapy would offer an opportunity to control residual cancer cells. This review summarizes findings from fundamental research together with clinical data on the use of local anesthetics as anticancer standalone drugs or their combination with conventional treatments. We suggest that a better comprehension of the anticancer effects of local anesthetics at the preclinical and clinical levels may broadly improve the surgical treatment of cancer.

Local Anesthetics for Regional Anesthesia and Pain Management

2008 ◽  
pp. 811-838 ◽  
Author(s):  
Francis V. Salinas ◽  
Khalid Malik ◽  
Honorio T. Benzon
Keyword(s):  
Pain Management ◽  
Regional Anesthesia ◽  
Local Anesthetics

Regional Anesthesia Equipment

2020 ◽  
pp. 6-16
Keyword(s):  
Regional Anesthesia ◽  
Acute Pain ◽  
Local Anesthetics ◽  
Pain Medicine ◽  
Anesthesia Equipment

This chapter outlines the conditions, equipment, and documentation necessary for a successful regional anesthesia and acute pain medicine practice. Local Anesthetics and Additives

Recovery and Discharge for Procedures Conducted Outside of the Operating Room

2011 ◽  
pp. 37-41
Author(s):  
Lianfeng Zhang ◽  
Frances F. Chung
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Operating Room ◽  
Regional Anesthesia ◽  
Postoperative Care ◽  
Postoperative Recovery ◽  
Therapeutic Interventions ◽  
Postanesthesia Care Unit ◽  
Discharge Process ◽  
Step Down

Continued advances in procedural techniques, anesthetic pharmacology, and regional anesthesia allow more prolonged diagnostic and therapeutic interventions to be conducted at an increasing variety of locations outside of the operating room (OOOR). However, recovery and discharge process may vary according to the patient’s condition and the specifics of the procedure. Generally, most patients are sent to the postanesthesia care unit (PACU) and ambulatory surgery unit (ASU) or a medical post-procedure recovery unit not staffed by an anesthesiologist, while some patients receive special postoperative care in a step-down or intensive care unit. Therefore, ensuring rapid postoperative recovery and safe discharge are important components following these OOOR procedures.

Regional Anesthesia Equipment

2019 ◽  
pp. 369-378
Keyword(s):  
Regional Anesthesia ◽  
Acute Pain ◽  
Local Anesthetics ◽  
Pain Medicine ◽  
Anesthesia Equipment

This chapter outlines the conditions, equipment, and documentation necessary for a successful regional anesthesia and acute pain medicine practice. Local Anesthetics and Additives

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