CYTOPATHOLOGICAL SPECTRUM OF NON NEOPLASTIC AND NEOPLASTIC THYROID LESIONS AT TERTIARY CARE CENTRE, GWALIOR

2021 ◽  
pp. 13-15
Author(s):  
Sapna Dhakad ◽  
Shailendra Sharma ◽  
Diljeet Kaur

Background: Thyroid lesions are the important clinical problems encountered in most of patients coming to the tertiary care centre. Fine Needle Aspiration Cytology (FNAC) is the widely accepted diagnostic technique in thyroid lesions. A solitary thyroid nodule is dened as a palpable, single, clinically detectable nodule in the thyroid. They cause more concern because of high probability of malignancy in them, which can range from 5-35% of all solitary thyroid nodules. Nodular lesion comprises those disorders that produce a clinical nodule and consists of non-neoplastic hyperplasia as well as benign and malignant tumors. Aims and Objectives:To study the spectrum of clinical presentation of individuals with thyroid lesions and cytomorphological features. Material and methods: A retrospective study was carried out in cytopathology section in Department of Pathology from January 2015 to December 2017. Total 212 patients with palpable thyroid swelling referred from the OPD of J.A hospital for FNAC were included in the study. The smears made from the aspirate were air dried and stained with May-Grunwald-Giemsa (MGG) stain. Result: The present study was carried out in the Department of Pathology from January 2015 to December 2017. Out of 212 cases most common thyroid lesion was Colloid goitre 35.38%(n=75) followed by Colloid goitre with cystic changes 19.81%(n=42), Follicular Neoplasm 19.34%(n=41), Hashimoto thyroiditis 7.55%(n=16), Colloid cyst 6.13%(n=13), Infected cystic lesion 2.83%(n=6), Benign hyperplasia of thyroid 2.36%(n=5), Adenomatoid goitre 1.89%(n=4), Thyroglossal cyst 1.89%(n=4), Granulomatous thyroiditis 1.41%(n=3), Papillary thyroid carcinoma 0.94%(n=2) and least common was Lymphoma of thyroid 0.47%(n=1). Conclusion: FNAC is almost an accurate technique in diagnosis of palpable and overt thyroid lesions. Thyroid lesions are more common in females than males. Colloid goitre is the commonest thyroid lesion.

2017 ◽  
Vol 8 (3) ◽  
pp. 72-75
Author(s):  
Amit Gupta ◽  
Lovenish Bains ◽  
Deepshikha Yadav ◽  
Prashant Durgapal ◽  
Manish Kumar Agrawal

Background: Tuberculous mastitis (TM) is a rare extra pulmonary presentation of tuberculosis. It may be problematic to distinguish from carcinoma breast, a condition with which it may coexist.  Fine needle aspiration cytology (FNAC) / biopsy are indispensable for diagnosis and tuberculosis culture when positive may be very valuable to guide antimicrobial therapy.Aims and Objectives:  To disseminate the message to the concerned expertise that it can present a diagnostic problem on radiological and microbiological investigations, and thus a high index of suspicion is needed.Materials and Methods: 19 cases of tubercular mastitis between  January 2012 to March 2014 were identified and included in the present study. Cytology and biopsy alongwith AFB stain was done for confirmation.Results: Age ranged between 23- 55 years (median 33 years). Axillary nodes were palpable in 9 (47.3%) patients. Acid Fast Bacilli stain which was positive in only 3 patients. All the 19 patients were started on antitubercular treatment.Conclusion: This study highlights the importance of early diagnosis and aggressive medical and if required surgical management to cure this disease.Asian Journal of Medical Sciences Vol.8(3) 2017 72-75


Author(s):  
Dharmendra Singh Bhadouria ◽  
Shikha Raghuwanshi ◽  
Arun Saxena

Introduction: Thyroid nodules show an overall incidence rate of 4-7% & high probability of malignancy, constituting 5% to 35%. FNAC of Thyroid is most economical and reliable preoperative procedure to distinguish between neoplastic and non- neoplastic lesion. Objectives: To Study Cyto-Morphology of Fine Needle Aspiration of Thyroid nodules. To find out incidence of various types of lesions as per age & sex and to confirm the findings with Histomorphological diagnosis of same nodule. Material & Methods: 100 patients with Thyroid nodule who underwent FNAC & Thyroidectomy taken for an observational study from January 2019 to June 2020. The cytological findings were correlated with histopathological diagnosis. Results: Out of 100 cases 14 cases were  found to be malignant and 86 were found to be benign on histology while cytology showed 93 cases benign and 7  malignant cases .Out of 5 cases suspicious for neoplasm and 3 cases were of follicular neoplasm on cytology which confirmed as papillary carcinoma on histopathology.2 cases which were diagnosed as Benign Thyroid lesion turned out to be papillary carcinoma and 2 cases which were diagnosed as colloid goitre on cytology turned out to be papillary carcinoma on histo pathology .1 case diagnosed as follicular hyperplasia turned out to be papillary carcinoma on histology.1 case diagnosed as MNG in cytology was turned out to be papillary carcinoma on histo pathology. Conclusion: Thyroid cytology proves to be a reliable, simple and cost-effective first line diagnostic procedure with high patient acceptance and without complications. FNAC serves as useful screening test for thyroid lesions. However, inability in distinguishing follicular lesion and inadequate sampling in cystic lesion lead to false diagnosis. Keywords: Histopathology, Thyroid , Lesion.


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