BACKGROUND: Hypocalcaemia is a common early complication occurring in post thyroidectomypatients. The aim of this study was determine the frequency of hypocalcaemia serum calcium level lessthen (8.2mg/dl) in patients who were operated upon for guiltier.OBJECTIVES: The objectives of the study, was to determine the frequency of hypocalcaemia in postthyroidectomy patients.PATIENTS AND METHODS: This is a descriptive, prospective study. The study was conducted inthe Department Of Surgery, Saidu Group of Teaching Hospital, Saidu Sharif Swat from January 2011 toJune 2014. Total of ninety patients were included in the study, these were the patients who underwenttotal or near total thyroidectomy for any primary disease of thyroid gland like multinodular goiter andcarcinoma thyroid gland, irrespective of their ages and gender.Patients undergoing lobectomy, subtotal or completion thyroidectomy as the risk of developinghypocalcaemia is very low in these procedures, as well as patients having other medical problemscausing hypocalcaemia like Chronic Renal Failure ,acid base imbalance and osteomalacia, all of thesewere excluded from study. Patients were divided into two groups, group a total thyroidectomy and groupB near total thyroidectomy. Preoperative serum ca++ level determined in all patients and then repeated onthe first post surgery day, and any decrease in serum ca++level noted in both groups.RESULTS: Results obtained were tabulated and analyzed. 48 patients(53%) of patients were more than40 years of age and there was female preponderance. 18 patients (20% )of patients developedhypocalcaemia on the first post-operative day.30 patients(33.4%) of patients had symptoms ofhypocalcaemia on first post-operative day.CONCLUSION: Symptomatically and statistically significant post-operative hypocalcaemia is mostcommon in the first postoperative day but prompt diagnosis is possible to institute treatment.KEYWORD: Serum calcium levels, Post-operative, Thyroidectomy patients