scholarly journals Experimental Study of Using a 3-D Position Sensitive CdZnTe Detector for Proton Beam Range Verification

2021 ◽  
Author(s):  
Valerie Nwadeyi ◽  
Paul maggi ◽  
Zhong He ◽  
Jerimy Polf
Keyword(s):  
Proton Beam ◽  
Expectation Maximization ◽  
Gamma Ray ◽  
Prompt Gamma ◽  
Cdznte Detector ◽  
Maximum Likelihood Expectation Maximization ◽  
Gamma Ray Imaging ◽  
Position Sensitive ◽  
Beam Range ◽  
Range Verification

This manuscript discusses the use of a large volume array CZT detector for experimental prompt gamma-ray imaging. Namely, the 718 keV and the 4.44 MeV photopeaks produced from proton-carbon interactions are imaged using maximum likelihood expectation maximization (MLEM). Various proton beam irradiations are used to characterize the feasibility of using both photopeaks for beam range verification.

scholarly journals Experimental Study of Using a 3-D Position Sensitive CdZnTe Detector for Proton Beam Range Verification

2021 ◽  
Author(s):  
Valerie Nwadeyi ◽  
Paul maggi ◽  
Zhong He ◽  
Jerimy Polf
Keyword(s):  
Proton Beam ◽  
Expectation Maximization ◽  
Gamma Ray ◽  
Prompt Gamma ◽  
Cdznte Detector ◽  
Maximum Likelihood Expectation Maximization ◽  
Gamma Ray Imaging ◽  
Position Sensitive ◽  
Beam Range ◽  
Range Verification

This manuscript discusses the use of a large volume array CZT detector for experimental prompt gamma-ray imaging. Namely, the 718 keV and the 4.44 MeV photopeaks produced from proton-carbon interactions are imaged using maximum likelihood expectation maximization (MLEM). Various proton beam irradiations are used to characterize the feasibility of using both photopeaks for beam range verification.

scholarly journals Experimental Study of Using a 3-D Position Sensitive CdZnTe Detector for Proton Beam Range Verification

2021 ◽  
Author(s):  
Valerie Nwadeyi ◽  
Paul maggi ◽  
Zhong He ◽  
Jerimy Polf
Keyword(s):  
Proton Beam ◽  
Expectation Maximization ◽  
Gamma Ray ◽  
Prompt Gamma ◽  
Cdznte Detector ◽  
Maximum Likelihood Expectation Maximization ◽  
Gamma Ray Imaging ◽  
Position Sensitive ◽  
Beam Range ◽  
Range Verification

This manuscript discusses the use of a large volume array CZT detector for experimental prompt gamma-ray imaging. Namely, the 718 keV and the 4.44 MeV photopeaks produced from proton-carbon interactions are imaged using maximum likelihood expectation maximization (MLEM). Various proton beam irradiations are used to characterize the feasibility of using both photopeaks for beam range verification.

scholarly journals Experimental Study of Using a 3-D Position Sensitive CdZnTe Detector for Proton Beam Range Verification

2021 ◽  
Author(s):  
Valerie Nwadeyi ◽  
Paul maggi ◽  
Zhong He ◽  
Jerimy Polf
Keyword(s):  
Proton Beam ◽  
Gamma Ray ◽  
Incident Angle ◽  
Prompt Gamma ◽  
Compton Imaging ◽  
Cdznte Detector ◽  
Maximum Likelihood Expectation Maximization ◽  
Position Sensitive ◽  
Beam Range ◽  
Range Verification

<p><i>Position sensitive CdZnTe Compton imaging cameras are currently being studied for their use of proton beam range verification for radiotherapy applications. This work presents the use of an experimental large volume CdZnTe detector for the detection of prompt gamma rays that are emitted from proton-nuclei interaction within plastic (C2H4) targets. Two experiments were conducted where the incident angle and the dose profile of the beam were varied. The energy spectra from these experiments show that the angle at which the beam enters the target can influence the photopeak to Compton continuum ratios, resulting in more than 18% increase at 718 keV when the beam is parallel to the detector. Images of the 718 keV and 4.44 MeV characteristic prompt gamma ray emission from carbon-proton interactions are reconstructed using list-mode maximum likelihood expectation maximization (MLEM). Images from these prompt gamma emissions line up well with the expected location of the proton beam within the plastic targets.</i><br></p>

WE-D-BRF-03: Proton Beam Range Verification with a Single Prompt Gamma-Ray Detector

2014 ◽  
Vol 41 (6Part29) ◽  
pp. 495-495
Author(s):  
J Verburg ◽  
M Testa ◽  
E Cascio ◽  
T Bortfeld ◽  
H Lu ◽  
...  
Keyword(s):  
Proton Beam ◽  
Gamma Ray ◽  
Prompt Gamma ◽  
Gamma Ray Detector ◽  
Beam Range ◽  
Range Verification

scholarly journals Characterization of prompt gamma-ray emission with respect to the Bragg peak for proton beam range verification: A Monte Carlo study

2017 ◽  
Vol 33 ◽  
pp. 197-206 ◽  
Author(s):  
Melek Zarifi ◽  
Susanna Guatelli ◽  
David Bolst ◽  
Brian Hutton ◽  
Anatoly Rosenfeld ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Proton Beam ◽  
Bragg Peak ◽  
Gamma Ray ◽  
Monte Carlo Study ◽  
Prompt Gamma ◽  
Gamma Ray Emission ◽  
Beam Range ◽  
Range Verification

scholarly journals 3D prompt gamma imaging for proton beam range verification

2018 ◽  
Vol 63 (3) ◽  
pp. 035019 ◽  
Author(s):  
E Draeger ◽  
D Mackin ◽  
S Peterson ◽  
H Chen ◽  
S Avery ◽  
...  
Keyword(s):  
Proton Beam ◽  
Prompt Gamma ◽  
Gamma Imaging ◽  
Prompt Gamma Imaging ◽  
Beam Range ◽  
Range Verification

scholarly journals Time-Encoded Gamma-Ray Imaging Using a 3-D Position-Sensitive CdZnTe Detector Array

2020 ◽  
Vol 67 (2) ◽  
pp. 464-472
Author(s):  
Steven T. Brown ◽  
David Goodman ◽  
Jiyang Chu ◽  
Bennett Williams ◽  
Martin R. Williamson ◽  
...  
Keyword(s):  
Gamma Ray ◽  
Detector Array ◽  
Cdznte Detector ◽  
Gamma Ray Imaging ◽  
Position Sensitive

scholarly journals A Study of The Clinical Viability of A Prototype Compton Camera for Prompt Gamma Imaging Based Proton Beam Range Verification

2021 ◽  
Author(s):  
Jerimy Polf ◽  
Carlos A. Barajas ◽  
Gerson C. Kroiz ◽  
Stephen W. Peterson ◽  
Paul Maggi ◽  
...  
Keyword(s):  
Proton Beam ◽  
Prompt Gamma ◽  
Reconstruction Algorithms ◽  
Compton Camera ◽  
Detection Rates ◽  
Proton Beams ◽  
Proton Beam Radiotherapy ◽  
Beam Range ◽  
Range Verification

Abstract We present Compton camera (CC) based PG imaging for proton range verification at clinical dose rates. PG emission from a tissue-equivalent phantom during irradiation with clinical proton beams was measured with a prototype CC. Images were reconstructed of the raw measured data and of data processed with a neural network (NN) trained to identify “true” and “false” PG events. From these images, we determine if PG images produced by the prototype CC could provide clinically useful information about the in vivo range of the proton beams delivered during proton beam radiotherapy. NN processing of the data was found necessary to allow identification of the proton beam path from the PG images. Furthermore, to allow the localization of the end of the proton beam range with a precision of ≤ 3mm with the prototype CC, ~1 x 109 protons would need to be delivered, which is on the order of magnitude delivered for a standard proton radiotherapy treatment field. To obtain higher precision in beam range determination and to allow imaging a single proton pencil beam delivered within the full treatment field, further improvements in PG detection rates by the CC, NN data processing, and image reconstruction algorithms are needed.

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