scholarly journals Deep margin elevation: a systematic review

2021 ◽  
Vol 19 (3) ◽  
pp. 175-183
Author(s):  
Z. S. Khabadze ◽  
I. V. Bagdasarova ◽  
E. S. Shilyaeva ◽  
A. P. Kotelnikova ◽  
D. A. Nazarova ◽  
...  
Keyword(s):  
Systematic Review ◽  
Resin Composite ◽  
Apical Part ◽  
In Vitro Studies ◽  
Clinical Observations ◽  
Direct Restoration ◽  
Deep Margin ◽  
The Difference ◽  
Crown Lengthening

Deep margin elevation (DME) is a nonsurgical, alternative technique of dental crown lengthening. Portion of direct restoration placed only at the deep apical part of the cavity to elevate the margin to a more coronal and more adequate position for final cementation of indirect restoration.Materials and methods. In this systematic review, we were looking for in vitro studies in which deep margin elevation (DME) technique were used. The electronic databases PubMed and EMBASE were used for the search. The search began on July 29, 2021 and ended on August 10, 2021. We have analyzed the materials and methods of each research and entered them in the appropriate tables to give a clearer assessment of the obtained results.Results. Analysis of marginal quality showed the best results when indirect restorations luted to dentin directly and with DME technique with three consecutive layers of resin composite. In groups without DME there were fewer microleakage. DME did not statistically significantly influence the fracture strength.Conclusions. We conducted a systematic review that included 12 in vitro studies. Even though samples without DME showed better results in in vitro studies, the difference between samples with and without DME was not statistically significant. However, in clinical practice, DME facilitates the insertion of indirect restorations. Therefore, further studies and clinical observations are necessary. 

Transplantation of Adipose-derived Cells for Periodontal Regeneration: A Systematic Review

2019 ◽  
Vol 14 (6) ◽  
pp. 504-518 ◽  
Author(s):  
Dilcele Silva Moreira Dziedzic ◽  
Bassam Felipe Mogharbel ◽  
Priscila Elias Ferreira ◽  
Ana Carolina Irioda ◽  
Katherine Athayde Teixeira de Carvalho
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Platelet Rich Plasma ◽  
Periodontal Regeneration ◽  
In Vitro Studies ◽  
In Vivo Studies ◽  
Cell Sources ◽  
Study Designs

This systematic review evaluated the transplantation of cells derived from adipose tissue for applications in dentistry. SCOPUS, PUBMED and LILACS databases were searched for in vitro studies and pre-clinical animal model studies using the keywords “ADIPOSE”, “CELLS”, and “PERIODONTAL”, with the Boolean operator “AND”. A total of 160 titles and abstracts were identified, and 29 publications met the inclusion criteria, 14 in vitro and 15 in vivo studies. In vitro studies demonstrated that adipose- derived cells stimulate neovascularization, have osteogenic and odontogenic potential; besides adhesion, proliferation and differentiation on probable cell carriers. Preclinical studies described improvement of bone and periodontal healing with the association of adipose-derived cells and the carrier materials tested: Platelet Rich Plasma, Fibrin, Collagen and Synthetic polymer. There is evidence from the current in vitro and in vivo data indicating that adipose-derived cells may contribute to bone and periodontal regeneration. The small quantity of studies and the large variation on study designs, from animal models, cell sources and defect morphology, did not favor a meta-analysis. Additional studies need to be conducted to investigate the regeneration variability and the mechanisms of cell participation in the processes. An overview of animal models, cell sources, and scaffolds, as well as new perspectives are provided for future bone and periodontal regeneration study designs.

scholarly journals Effect of Composite Core Materials on Fracture Resistance of Endodontically Treated Teeth: A Systematic Review and Meta-Analysis of In Vitro Studies

Polymers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 2251
Author(s):  
Maciej Zarow ◽  
Marzena Dominiak ◽  
Katarzyna Szczeklik ◽  
Louis Hardan ◽  
Rim Bourgi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Fracture Resistance ◽  
Meta Analysis ◽  
Cochrane Collaboration ◽  
Composite Resins ◽  
In Vitro Studies ◽  
Endodontically Treated Teeth ◽  
The Cochrane Collaboration ◽  
Core Materials

Various material properties are involved in the success of endodontically treated restorations. At present, restorative composites are commonly employed as core build-up materials. This study aimed to systematically review the literature to assess the effect of using composite core materials on the in vitro fracture of endodontically treated teeth. Two different reviewers screened the literature, up to June 2021, in five distinct electronic databases: PubMed (MedLine), Scopus, Scielo, ISI Web of Science, and EMBASE. Only in vitro studies reporting the effect of the use of composite core materials on the fracture resistance of endodontically treated teeth were included. A meta-analysis was carried out using a software program (Review Manager v5.4.1; The Cochrane Collaboration, Copenhagen, Denmark). The risk of bias in each study was assessed following the parameters of another systematic review. A total of 5016 relevant papers were retrieved from all databases. After assessing the title and abstract, five publications remained for qualitative analysis. From these, only three studies remained for meta-analysis. The fracture strength of endodontically treated teeth where a core build-up composite was used was statistically significantly higher than the control (p = 0.04). Most of the analyses showed a high heterogenicity. The in vitro evidence suggests that the composite core build-up with higher filler content tended to improve the fracture resistance of the endodontically treated teeth, in comparison with conventional composite resins. This research received no external funding. Considering that this systematic review was only carried out on in vitro papers, registration was not performed. Furthermore, there were no identified clinical studies assessing core build-up materials; therefore, more well-designed research on these materials is needed.

scholarly journals Effect of exercise-conditioned human serum in hallmarks of cancer: systematic review and meta-analysis of in vitro studies

2020 ◽  
Author(s):  
Carlos Soares ◽  
Ana Teixeira ◽  
Hugo Sarmento ◽  
Ana Urbano ◽  
Fernanda Silva ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Serum ◽  
Meta Analysis ◽  
In Vitro Studies ◽  
Hallmarks Of Cancer

Effectiveness of ultrasonically activated irrigation on root canal disinfection: a systematic review of in vitro studies

2018 ◽  
Vol 22 (2) ◽  
pp. 655-670 ◽  
Author(s):  
Venkateshbabu Nagendrababu ◽  
Jayakumar Jayaraman ◽  
Anand Suresh ◽  
Senthilnayagam Kalyanasundaram ◽  
Prasanna Neelakantan
Keyword(s):  
Systematic Review ◽  
Root Canal ◽  
In Vitro Studies ◽  
Root Canal Disinfection

Hydroxyapatite, a potent agent to reduce dentin hypersensitivity; systematic review

2021 ◽  
Vol 71 (11) ◽  
pp. 2604-2610
Author(s):  
Hashmat Gul ◽  
Muhammad Asad Ghaffar ◽  
Muhammad Kaleem ◽  
Abdul Samad Khan
Keyword(s):  
Systematic Review ◽  
Literature Search ◽  
Web Of Science ◽  
In Vitro Studies ◽  
Dentin Hypersensitivity ◽  
Dentinal Tubule ◽  
Dentin Permeability ◽  
Tubule Occlusion

Objective: This study reviews different modes of application of hydroxyapatite for treatment of dentin hypersensitivity via dentinal tubule occlusion. Methods: Literature search was performed using keywords, “hydroxyapatite and dentin hypersensitivity, hydroxyapatite and dentinal tubule occlusion, hydroxyapatite and dentin permeability, dentinal tubule occlusion” on Pubmed, Science Direct and Web of Science, which involved the results of previous 10 years (2009-2018). After screening, 16 studies were included in systematic review. Results: The results of in-vitro studies showed that application of hydroxyapatite caused dentinal tubule occlusion leading to reduction in dentin permeability and reduction in dentin hypersensitivity. Conclusion: Hydroxyapatite has the potential to reduce dentin hypersensitivity via dentinal tubule occlusion within 2-8 weeks. Keywords: Dentin hypersensitivity, Hydroxyapatite, Dentinal tubule occlusion. Continuous...

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