scholarly journals PRIMARY GASTROINTESTINAL STROMAL TUMOUR OF THE PROSTATE: A CASE REPORT OF A RARE TUMOUR

2018 ◽  
Vol 4 (2) ◽  
Author(s):  
Muhammad Arshad Irshad Khalil ◽  
Nouman Khan ◽  
Azfar Ali ◽  
Khurram Mir
Keyword(s):  
Case Report ◽  
Prostate Specific Antigen ◽  
Bladder Outlet Obstruction ◽  
Specific Antigen ◽  
Outlet Obstruction ◽  
Gastrointestinal Stromal Tumour ◽  
Stromal Tumour ◽  
Rare Tumour ◽  
Normal Prostate

A 70-year-old gentleman underwent prostatectomy for bladder outlet obstruction due to enlarged prostate and was found to have primary extragastrointestinal stromal tumour (EGIST). He has been started on imatinib therapy and is presently on follow-up. Prostatic EGIST should be one of the differential diagnoses in patients with enlarged prostate with normal prostate-specific antigen levels.Key words: Prostate, gastrointestinal stromal tumour, PSA  

scholarly journals Solitary Lung Metastasis of Prostate Cancer with a Long Disease-Free Interval and Normal Prostate-Specific Antigen Level

2021 ◽  
pp. 284-289
Author(s):  
Hiroyuki Yoshitake ◽  
Shoji Oura ◽  
Tomoyuki Yamaguchi ◽  
Shinichiro Makimoto
Keyword(s):  
Prostate Cancer ◽  
Prostate Specific Antigen ◽  
Lung Metastasis ◽  
Specific Antigen ◽  
Middle Lobe ◽  
Primary Adenocarcinoma ◽  
Wide Resection ◽  
Normal Prostate ◽  
Solid Nodule

An 83-year-old man with core needle biopsy-proven Gleason score 5 prostate cancer had received radiotherapy including 18 Gy brachytherapy to the prostate cancer, leading to no locoregional and distant recurrence for more than 5 years with the normalization of elevated prostate-specific antigen (PSA) level before the radiotherapy. Due to the enlargement of coexisting ground glass nodule (GGN) in the left lung from 1 to 2.1 cm, the patient underwent wide resection of the GGN 7 years later. Under the diagnosis of adenocarcinoma in situ of the lung, follow-up computed tomography 6 months after the wide resection showed a rapid enlargement of a solid nodule having been judged as a presumed inflammatory nodule in the middle lobe, highly suggesting a malignant neoplasm of the lung. Due to both the tall columnar atypical cells with trabecular pattern on frozen section and no elevation of serum PSA level, we judged the nodule as a primary adenocarcinoma of the lung and further resected the middle lobe with lymph node dissection. Immunostaining of the tumor showed all the CK7, CK20, TTF-1, napsin A, synaptophysin, chromogranin, CD56, CDX2, p53, beta-catenin, and MUC2 negative, and PSA highly positive, clearly showing the solid nodule as a solitary lung metastasis of the prostate cancer. Physicians should note the possible solitary lung metastasis of prostate cancer, especially bearing indolent biology, with no elevation of the PSA level even after the completion of standard 5-year follow-up.

Recurrent paediatric gastrointestinal stromal tumour of the stomach after 11-years follow-up period – Case report and review of the literature

2021 ◽  
Vol 11 (4) ◽  
pp. 184
Author(s):  
MieAli Mohamed ◽  
KhadigaM Ali ◽  
IkbalA Elkholy ◽  
AhmedY Altonbary ◽  
Ahmed Abdallah ◽  
...  
Keyword(s):  
Case Report ◽  
Gastrointestinal Stromal Tumour ◽  
Stromal Tumour ◽  
Review Of The Literature

Serum prostate-specific antigen to predict the presence of bladder outlet obstruction in men with urinary symptoms

2004 ◽  
Vol 94 (9) ◽  
pp. 1283-1286 ◽  
Author(s):  
Marc E. Laniado ◽  
Jeremy L. Ockrim ◽  
Angelo Marronaro ◽  
Andrea Tubaro ◽  
Simon S. Carter
Keyword(s):  
Prostate Specific Antigen ◽  
Bladder Outlet Obstruction ◽  
Specific Antigen ◽  
Outlet Obstruction ◽  
Urinary Symptoms ◽  
Serum Prostate Specific Antigen

scholarly journals CORRELATION OF PSA, PV, AND IPP IN DETECTING BOO CAUSED BY PROSTATE ENLARGEMENT

2014 ◽  
Vol 21 (2) ◽  
Author(s):  
Indra Cahya Kurnia ◽  
Tanaya Ghinorawa ◽  
Sungsang Rochadi
Keyword(s):  
Prostate Specific Antigen ◽  
Bladder Outlet Obstruction ◽  
Prostate Volume ◽  
Specific Antigen ◽  
Outlet Obstruction ◽  
Roc Curves ◽  
Transabdominal Ultrasound ◽  
Prostate Hyperplasia ◽  
Predictive Values ◽  
Intravesical Prostatic Protrusion

Objective: To define the relationship between intravesical prostatic protrusion (IPP), prostate specific antigen (PSA), and prostate volume (PV), and to determine which one is the best predictor of bladder outlet obstruction (BOO) due to benign prostatic enlargement. Material & method: 95 male patients > 40 years old presenting with LUTS and BPH, between January until July 2012. They were evaluated with digital rectal examination (DRE), International Prostate Symptoms Score (IPSS), total PSA serum, uroflowmetry, post-void residual urine measurement, IPP and PV using transabdominal ultrasound. Statistical analysis included Chi-square and Spearman’s Rank correlation test.Receiver Operator Characteristic (ROC) curves were used to evaluate the correlation of PSA, PV, and IPP with BOO. Results: Mean PSA was significantly higher in obstructed patients (8.6 ng/mL; 0.76-130) compared to non-obstructed patients (6.44 ng/mL; 1.0-40.6). Mean PV was significantly larger in obstructed patients (50.33 mL ± 24.34) compared to non-obstructed patients (45.39 mL ± 23.43). Mean IPP was significantly greater in obstructed patients (7.29 ± 2.78) compared to non-obstructed patients (6.59 ± 2.93). The Spearman rho correlation coefficients were 0.617, 0.721, and 0.797, for PSA, PV, and IPP, respectively. Using ROC curves, the areas under the curve for PSA, PV, and IPP were 0.509, 0.562 and 0.602, respectively. The positive predictive values of PV, PSA, and IPP were 59.7%, 55.6% and 60.2% respectively. Conclusion: PSA, PV, and IPP measured through transabdominal ultrasonography are noninvasive and accessible method that significantly correlates with BOO in BPH patients. IPP is a better predictor for BOO than PSA or PV.Keywords: Bladder outlet obstruction, intravesical prostatic protrusion, prostate specific antigen, prostate volume, transabdominal ultrasound, benign prostate hyperplasia.

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