scholarly journals Characteristics and outcomes of acute upper gastrointestinal bleeding after therapeutic endoscopy in the elderly

2011 ◽  
Vol 17 (32) ◽  
pp. 3724 ◽  
Author(s):  
Phunchai Charatcharoenwitthaya
2011 ◽  
Vol 140 (5) ◽  
pp. S-741
Author(s):  
Phunchai Charatcharoenwitthaya ◽  
Nonthalee Pausawasdi ◽  
Nuttiya Laosanguaneak ◽  
Jakkrapan Bubthamala ◽  
Tawesak Tanwandee ◽  
...  

Gut ◽  
2021 ◽  
pp. gutjnl-2020-323054
Author(s):  
Cosmos L T Guo ◽  
Sunny H Wong ◽  
Louis H S Lau ◽  
Rashid N S Lui ◽  
Joyce W Y Mak ◽  
...  

ObjectiveWhile it is recommended that patients presenting with acute upper gastrointestinal bleeding (AUGIB) should receive endoscopic intervention within 24 hours, the optimal timing is still uncertain. We aimed to assess whether endoscopy timing postadmission would affect outcomes.DesignWe conducted a retrospective, territory-wide, cohort study with healthcare data from all public hospitals in Hong Kong. Adult patients (age ≥18) that presented with AUGIB between 2013 and 2019 and received therapeutic endoscopy within 48 hours (n=6474) were recruited. Patients were classified based on endoscopic timing postadmission: urgent (t≤6), early (6<t≤24) and late (24<t≤48). Baseline characteristics were balanced with inverse probability of treatment weighting. 30-day all-cause mortality, repeated therapeutic endoscopy rate, intensive care unit (ICU) admission rate and other endpoints were compared.ResultsResults showed that urgent timing (n=1008) had worse outcomes compared with early endoscopy (n=3865), with higher 30-day all-cause mortality (p<0.001), repeat endoscopy rates (p<0.001) and ICU admission rates (p<0.001). Late endoscopy (n=1601) was associated with worse outcomes, with higher 30-day mortality (p=0.003), in-hospital mortality (p=0.022) and 30-day transfusion rates (p=0.018).ConclusionCompared with urgent and late endoscopy among patients who have received therapeutic endoscopies, early endoscopy was associated with superior outcomes especially among patients with non-variceal bleeding. This supports the notion that non-variceal AUGIB patients should receive endoscopy within 24 hours, but also emphasises the importance of prior resuscitation and pharmacotherapy.


2011 ◽  
Vol 140 (5) ◽  
pp. S-397
Author(s):  
Priya Rangasamy ◽  
Haleh Vaziri ◽  
Tarun Rustagi ◽  
Maria E. Soriano ◽  
Deepika Devuni ◽  
...  

2007 ◽  
Vol 54 (1) ◽  
pp. 145-150 ◽  
Author(s):  
D. Popovic ◽  
V. Stankovic-Popovic ◽  
I. Jovanovic ◽  
M.N. Krstic ◽  
S. Djuranovic ◽  
...  

Introduction: Acute upper gastrointestinal bleeding is the commonest emergency managed by gastroenterologists. It manifests like: haematemesis, melaena or haemochezia. Diagnostic endoscopy accurately defining the cause of hemorrhage, while therapeutic endoscopy improves prognosis in patients who present with severe bleeding. Endoscopic therapies can be classified as those based on injection, application of heat, or mechanical clips. Patients and methods: This investigation was conducted in Department of endoscopic haemostasis, Clinic for gastroenterology and hepatology, CCS, using retrospective analysis of patients with acute upper gastrointestinal bleeding during the last five years. The aim of this study was to establish the number of upper gastrointestinal bleeding in our hospital during the last five years, and distribution of income according to type, difficulty, cause factors and risk factors of gastrointestinal bleeding and method of haemostasis. Results: In Department of endoscopic haemostasis 3954 patients with upper gastrointestinal bleeding were endoscoped, and 33,4% of them had bleeding duodenal ulcer. Male patients were statistically significant more present than female patients in group with duodenal ulcer ( 71,8%: 28,2%). 79.7% patients with duodenal ulcer had only haematemesis, while 14,4% patients had haematemesis and melaena. 59,1% patients with bleeding duodenal ulcer consumed salicylates and/or non-steroidal anti-inflammatory drugs ( NSAIDS) ( statistical significant differences ?2 test; p=0.007). Only endoscopic injection was used: in 36.8% of patients used injection of adrenaline solutions, while in 5,9% of patients used injection of adrenaline and absolute alcohol solutions. Conclusion: Using of therapeutic endoscopy improves better prognosis in patients who present with severe acute upper gastrointestinal bleeding. Endoscopist?s experience is an important independent prognostic factor for acute upper gastrointestinal bleeding.


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