Electrocochleography in Guinea Pigs with Experimental Endolymphatic Hydrops

1992 ◽  
Vol 51 (Suppl-8) ◽  
pp. 20-23
Author(s):  
Kaoru Uchida ◽  
Masaaki Kitahara ◽  
Yoshiro Yazawa
Keyword(s):  
Guinea Pigs ◽  
Endolymphatic Hydrops

Correlation Between Hearing Loss and Scala Media Area in Guinea Pigs with Long-standing Endolymphatic Hydrops

2003 ◽  
Vol 24 (1) ◽  
pp. 64-72 ◽  
Author(s):  
Morgan E. Hott ◽  
Martin Graham ◽  
Lawrence J. Bonassar ◽  
Cliff A. Megerian
Keyword(s):  
Hearing Loss ◽  
Guinea Pigs ◽  
Endolymphatic Hydrops

Assessment of Cochlea Endolymphatic Hydrops Using 3-D FLAIR and 3-D Real IR Sequence in Guinea Pigs via 3T MRI After Intratympanic Gadolinium

2017 ◽  
Vol 38 (4) ◽  
pp. 585-590 ◽  
Author(s):  
Feng Wang ◽  
Huiying Lyu ◽  
Menglong Zhao ◽  
Yan Sha ◽  
Fang Zhang ◽  
...  
Keyword(s):  
Guinea Pigs ◽  
Endolymphatic Hydrops ◽  
3T Mri

Endolymphatic Hydrops Induced by Immune Response of the Endolymphatic Sac: Relation to Perilymph Antibody Levels

1992 ◽  
Vol 101 (10_suppl) ◽  
pp. 48-53 ◽  
Author(s):  
Shun-Ichi Tomiyama
Keyword(s):  
Immune Response ◽  
Vascular Permeability ◽  
Guinea Pigs ◽  
Endolymphatic Hydrops ◽  
Keyhole Limpet Hemocyanin ◽  
Endolymphatic Sac ◽  
Secondary Immune Response ◽  
Initial Stage ◽  
Antibody Levels

This study investigated the effect of a secondary immune response in the endolymphatic sac on the development of endolymphatic hydrops in guinea pigs. Following secondary keyhole limpet hemocyanin (KLH) challenge directly to the sac in systemically presensitized animals, hydrops rapidly developed within 1 week, then gradually reduced by 4 weeks. After 5 weeks, hydrops gradually recurred and developed again. Mean perilymph anti-KLH antibody levels rose from day 1 to 4 weeks and then decreased. The elevation of perilymph anti-KLH antibody levels on day 2 was due to an increased vascular permeability and there was a local regeneration by the challenge of the sac after day 7. The development of hydrops correlated well with mean perilymph anti-KLH antibody levels in the period from day 1 to day 7. After 2 weeks, there was no correlation between them. These results suggest that an immune response of the sac may induce an excess secretion of endolymph in the initial stage and may further lead to irreversible dysfunction of the sac at a later stage.

scholarly journals Hearing Preservation in Guinea Pigs With Long-Standing Endolymphatic Hydrops

2011 ◽  
Vol 32 (9) ◽  
pp. 1583-1589 ◽  
Author(s):  
Suhael R. Momin ◽  
Sami J. Melki ◽  
Joy O. Obokhare ◽  
Souha A. Fares ◽  
Maroun T. Semaan ◽  
...  
Keyword(s):  
Guinea Pigs ◽  
Endolymphatic Hydrops ◽  
Hearing Preservation

scholarly journals Effect of isosorbide on experimental endolymphatic hydrops in guinea pigs.

1990 ◽  
Vol 83 (3) ◽  
pp. 457-462
Author(s):  
Yoshiro Yazawa ◽  
Masaaki Kitahara
Keyword(s):  
Guinea Pigs ◽  
Endolymphatic Hydrops
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