scholarly journals TBHP-mediated highly efficient dehydrogenative cross-oxidative coupling of methylarenes with acetanilides

2016 ◽  
Vol 12 ◽  
pp. 2250-2255 ◽  
Author(s):  
Cui Chen ◽  
Weibing Liu ◽  
Peng Zhou
Keyword(s):  
Transition Metal ◽  
Organic Solvents ◽  
Oxidative Coupling ◽  
Cross Coupling ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Coupling Method ◽  
Highly Efficient ◽  
Coupling Approach

A TBHP-mediated dehydrogenative cross-oxidative-coupling approach has been developed for the synthesis of N-arylbenzamides from methylarenes and acetanilides. This cross-coupling method is free of transition metal catalysts and ligands, and no extra organic solvents are required, which make it an useful and attractive strategy for the straightforward construction of C–N bonds. Besides, this conversion is an important complement to the conventional C–N forming strategies.

Transition-Metal-Free Synthetic Strategies for the Cross-Coupling Reactions in Water: A Green Approach

2020 ◽  
Vol 07 ◽  
Author(s):  
Tanmay Chatterjee ◽  
Nilanjana Mukherjee
Keyword(s):  
Transition Metal ◽  
Organic Solvents ◽  
Aqueous Media ◽  
Cross Coupling ◽  
Transition Metal Catalysts ◽  
Synthetic Methods ◽  
Coupling Reactions ◽  
Organic Transformations ◽  
Green Approach ◽  
Dehydrogenative Coupling

Abstract: A natural driving force is always working behind the synthetic organic chemists towards the development of ‘green’ synthetic methodologies for the synthesis of useful classes of organic molecules having potential applications. The majority of the essential classes of organic transformations, including C-C and C-X (X = heteroatom) bond-forming crosscoupling reactions, cross dehydrogenative-coupling (CDC) mostly rely on the requirement of transition-metal catalysts and hazardous organic solvents. Hence, the scope in developing green synthetic strategies by avoiding the use of transitionmetal catalysts and hazardous organic solvents for those important and useful classes of organic transformations is very high. Hence, several attempts are made so far. Water being the most abundant, cheap, and green solvent in the world; numerous synthetic methods have been developed in an aqueous medium. In this review, the development of transitionmetal- free green synthetic strategies for various important classes of organic transformations such as C-C and C-X bondforming cross-coupling, cross dehydrogenative-coupling, and oxidative-coupling in an aqueous media is discussed.

Transition metal-free aroylation of NH-sulfoximines with methyl arenes

2015 ◽  
Vol 51 (80) ◽  
pp. 14889-14892 ◽  
Author(s):  
Ya Zou ◽  
Jing Xiao ◽  
Zhihong Peng ◽  
Wanrong Dong ◽  
Delie An
Keyword(s):  
Transition Metal ◽  
Organic Solvents ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Metal Free

An iodine-catalyzed N-aroylation of NH-sulfoximines with methyl arenes was herein demonstrated without participation of external organic solvents, transition metal-catalysts or ligands.

Eco-friendly electrocatalytic oxidation of alcohols on a novel electro generated TEMPO-functionalized MCM-41 modified electrode

2015 ◽  
Vol 17 (2) ◽  
pp. 991-1000 ◽  
Author(s):  
Babak Karimi ◽  
Mohammad Rafiee ◽  
Saber Alizadeh ◽  
Hojatollah Vali
Keyword(s):  
Transition Metal ◽  
Selective Oxidation ◽  
Modified Electrode ◽  
Electrocatalytic Oxidation ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Free System ◽  
Highly Efficient ◽  
Oxidation Of Alcohols ◽  
Mcm 41

The development of a highly efficient and waste-free system for the selective oxidation of alcohols without using expensive transition metal catalysts using a novel electrogenerated TEMPO-functionalized MCM-41 modified electrode is described.

Iodine-mediated synthesis of (E)-vinyl sulfones from sodium sulfinates and cinnamic acids in aqueous medium

RSC Advances ◽  
2015 ◽  
Vol 5 (82) ◽  
pp. 66723-66726 ◽  
Author(s):  
Jian Gao ◽  
Junyi Lai ◽  
Gaoqing Yuan
Keyword(s):  
Transition Metal ◽  
Aqueous Medium ◽  
Efficient Method ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Cinnamic Acids ◽  
Highly Efficient

A green and highly efficient method for the synthesis of (E)-vinyl sulfones promoted by iodine in water has been developed, without transition metal catalysts and ligands.

Synthesis of spiroketals by iridium-catalyzed double hydroalkoxylation

2006 ◽  
Vol 78 (2) ◽  
pp. 385-390 ◽  
Author(s):  
Barbara A. Messerle ◽  
Khuong Q. Vuong
Keyword(s):  
Transition Metal ◽  
Benzyl Alcohol ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Iridium Complex ◽  
Effective Catalyst ◽  
Efficient Approach ◽  
Highly Efficient

A highly efficient approach to the synthesis of spiroketals involves the double cyclization of alkynyl diols using transition-metal catalysts. The iridium complex [Ir(PyP)(CO)2]BPh4 where PyP = 1-[(2-diphenylphosphino)ethyl]pyrazole is an effective catalyst for promoting the formation of spiroketals via this double hydroalkoxylation reaction. The complex promotes the formation of a series of spiroketal products from alkynyl diol starting materials such as 3-ethynylpentane-1,5-diol and 2-(4-hydroxybut-1-ynyl)benzyl alcohol. Stereoselective cyclization occurs for 3-ethynylpentane-1,5-diol, 3-ethynylhexane-1,6-diol. The cycloadditions occur in all but one case with quantitative conversion in under 24 h at 120 °C.

scholarly journals Iodobenzene-catalyzed synthesis of aryl sulfonate esters from aminoquinolines via remote radical C–O cross-coupling

RSC Advances ◽  
2017 ◽  
Vol 7 (78) ◽  
pp. 49436-49439 ◽  
Author(s):  
Chao Shen ◽  
Ming Yang ◽  
Jun Xu ◽  
Chao Chen ◽  
Kai Zheng ◽  
...  
Keyword(s):  
Transition Metal ◽  
Cross Coupling ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Efficient Approach

A simple and efficient approach is established for the iodobenzene-catalyzed synthesis of aryl sulfonate esters from aminoquinolines via remote radical C–O cross-coupling in the absence of any transition metal catalysts.

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