One-pot synthesis of epoxides from benzyl alcohols and aldehydes
2018 ◽
Vol 14
◽
pp. 2308-2312
◽
Keyword(s):
One Pot
◽
A one-pot synthesis of epoxides from commercially available benzyl alcohols and aldehydes is described. The reaction proceeds through in situ generation of sulfonium salts from benzyl alcohols and their subsequent deprotonation for use in Corey–Chaykovsky epoxidation of aldehydes. The generality of the method is exemplified by the synthesis of 34 epoxides that were made from an array of electronically and sterically varied alcohols and aldehydes.
2015 ◽
Vol 13
(4)
◽
pp. 653-658
2015 ◽
Vol 11
◽
pp. 1265-1273
◽
1990 ◽
Vol 112
(20)
◽
pp. 7441-7442
◽
1996 ◽
Vol 24
(4)
◽
pp. 833-836
◽
2013 ◽
Vol 11
(10)
◽
pp. 1659
◽