scholarly journals Comparative efficacy and safety of different corticosteroids to reduce inflammatory complications after mandibular third molar surgery: a systematic review and network meta-analysis protocol

Author(s):  
Joao Vitor Canellas ◽  
◽  
Fabio Ritto ◽  
Paul Tiwana ◽  
◽  
...  

Review question / Objective: This systematic review aims to compare the effects of different corticosteroids to reduce postoperative inflammatory complications (pain, edema, and trismus) after mandibular third molar surgery by applying a frequentist network meta-analysis approach. To this end, the proposed study will answer the following questions: 1) Among diverse corticosteroids currently available, what is the best preoperative option to control postoperative inflammatory complications? 2) What is the optimal dose and route of administration of corticosteroids prior to mandibular third molar surgery to control the pain, edema, and trismus induced by the surgery? Condition being studied: Inflammatory complications after mandibular third molar surgery (Pain, edema, and trismus).

2021 ◽  
Author(s):  
Joao Vitor Canellas ◽  
◽  
Fabio Ritto ◽  
Paul Tiwana ◽  
◽  
...  

Review question / Objective: This systematic review aims to compare the effects of different drugs to reduce postoperative inflammatory complications (pain, edema, and trismus) after mandibular third molar surgery by applying a frequentist network meta-analysis approach. To this end, the proposed study will answer the following questions: 1) Among diverse drugs currently available, which postoperative pharmacological regimen is the most efficient to reduce pain after mandibular third molar surgery? 2) Is the pre-emptive analgesia effective in reducing pain immediately after the mandibular third molar surgery? In this case, 3) Which preoperative pharmacological regimen is the most efficient? 4) Among diverse corticosteroids currently available, what is the best option to control the edema induced by the surgery? 5) What is the optimal dose and route of administration of corticosteroids prior to mandibular third molar surgery to control the pain/ edema induced by the surgery? Condition being studied: Inflammatory complications after mandibular third molar surgery (Pain, edema, and trismus).


Author(s):  
Parsa Firoozi ◽  
Marina Rocha Fonseca Souza ◽  
Glaciele Maria de Souza ◽  
Ighor Andrade Fernandes ◽  
Endi Lanza Galvão ◽  
...  

2020 ◽  
Vol 48 (9) ◽  
pp. 902-913
Author(s):  
João Vitor dos Santos Canellas ◽  
Samira Regina Guimarães Fraga ◽  
Monike Fernandes Santoro ◽  
Juliana de Noronha Santos Netto ◽  
Eduardo Muniz Barretto Tinoco

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