scholarly journals Antimicrobial Susceptibility Testing of Mycobacterium Tuberculosis Complex for First and Second Line Drugs by Broth Dilution in a Microtiter Plate Format

10.3791/3094 ◽  
2011 ◽  
Author(s):  
Leslie Hall ◽  
Kurt P. Jude ◽  
Shirley L. Clark ◽  
Nancy L. Wengenack
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Mycobacterium Tuberculosis Complex ◽  
Microtiter Plate ◽  
Antimicrobial Susceptibility Testing ◽  
Second Line ◽  
Tuberculosis Complex ◽  
Broth Dilution ◽  
Microtiter Plate Format

scholarly journals Reliability of the MB/BacT System for Testing Susceptibility of Mycobacterium tuberculosis Complex Isolates to Antituberculous Drugs

2000 ◽  
Vol 38 (2) ◽  
pp. 872-873 ◽  
Author(s):  
Francesca Brunello ◽  
Roberta Fontana
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Mycobacterium Tuberculosis Complex ◽  
Antimicrobial Susceptibility Testing ◽  
Clinical Isolates ◽  
Tuberculosis Complex ◽  
Antituberculous Drugs ◽  
Testing Susceptibility

The susceptibility of 115 Mycobacterium tuberculosiscomplex clinical isolates to isoniazid, streptomycin, ethambutol, and rifampin was assessed by the MB/BacT and BACTEC 460TB systems. The correlation between the two tests was 98.3% for isoniazid, 100% for streptomycin and rifampin, and 95.8% for ethambutol. Turnaround times for antimicrobial susceptibility testing ranged from 5 to 11 days (median, 8.5 days) for MB/BacT and from 4 to 8 days (median, 6 days) for BACTEC 460TB.

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