scholarly journals Bone marrow mesenchymal stem cells combined with calcium alginate gel modified by hTGF-β1 for the construction of tissue-engineered cartilage in three-dimensional conditions

2012 ◽  
Vol 5 (1) ◽  
pp. 95-101 ◽  
Author(s):  
SHAOBO ZHU ◽  
TAO ZHANG ◽  
CHEN SUN ◽  
AIXI YU ◽  
BAIWEN QI ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Calcium Alginate ◽  
Three Dimensional ◽  
Alginate Gel ◽  
Marrow Mesenchymal Stem Cells ◽  
Calcium Alginate Gel ◽  
Engineered Cartilage

Quantitative Study of Tissue-Engineered Cartilage With Human Bone Marrow Mesenchymal Stem Cells

2005 ◽  
Vol 7 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Yonggang Pang ◽  
Pengcheng Cui ◽  
Wenxian Chen ◽  
Pengfei Gao ◽  
Huizhong Zhang
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Quantitative Study ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Marrow Mesenchymal Stem Cells ◽  
Engineered Cartilage

Different combinations of growth factors for the tenogenic differentiation of bone marrow mesenchymal stem cells in monolayer culture and in fibrin-based three-dimensional constructs

2017 ◽  
Vol 95 ◽  
pp. 44-53 ◽  
Author(s):  
Marta Bottagisio ◽  
Silvia Lopa ◽  
Valentina Granata ◽  
Giuseppe Talò ◽  
Chiara Bazzocchi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Growth Factors ◽  
Monolayer Culture ◽  
Three Dimensional ◽  
Tenogenic Differentiation ◽  
Marrow Mesenchymal Stem Cells

Bone augmentation by bone marrow mesenchymal stem cells cultured in three-dimensional biodegradable polymer scaffolds

2009 ◽  
Vol 91A (2) ◽  
pp. 428-435 ◽  
Author(s):  
Toshimitsu Tanaka ◽  
Motohiro Hirose ◽  
Noriko Kotobuki ◽  
Mika Tadokoro ◽  
Hajime Ohgushi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Biodegradable Polymer ◽  
Three Dimensional ◽  
Bone Augmentation ◽  
Polymer Scaffolds ◽  
Marrow Mesenchymal Stem Cells ◽  
Cells Cultured

Different Ratios of Bone Marrow Mesenchymal Stem Cells and Chondrocytes Used in Tissue-Engineered Cartilage and Its Application for Human Ear-Shaped Substitutes in vitro

2013 ◽  
Vol 198 (5) ◽  
pp. 357-366 ◽  
Author(s):  
Ning Kang ◽  
Xia Liu ◽  
Li Yan ◽  
Qian Wang ◽  
Yilin Cao ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Marrow Mesenchymal Stem Cells ◽  
Human Ear ◽  
Engineered Cartilage

scholarly journals Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs

EBioMedicine ◽  
2020 ◽  
Vol 53 ◽  
pp. 102698 ◽  
Author(s):  
Daisuke Ukeba ◽  
Hideki Sudo ◽  
Takeru Tsujimoto ◽  
Katsuro Ura ◽  
Katsuhisa Yamada ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Therapeutic Strategy ◽  
Intervertebral Discs ◽  
Alginate Gel ◽  
Marrow Mesenchymal Stem Cells ◽  
Degenerated Intervertebral Discs

scholarly journals Three-dimensional spheroid culture of canine hepatocyte-like cells derived from bone marrow mesenchymal stem cells

2020 ◽  
Vol 15 ◽  
pp. 210-215
Author(s):  
Suguru Nitta ◽  
Masaharu Hisasue ◽  
Yu Horiguchi ◽  
Yoko Yamada ◽  
Kaoruko Kikuchi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Three Dimensional ◽  
Spheroid Culture ◽  
Marrow Mesenchymal Stem Cells

EVALUATION OF THREE DIMENSIONAL CONSTRUCT ENGINEERED FROM POLY(LACTIC-CO-GLYCOLIC ACID)/FIBRIN HYBRID SCAFFOLD USING RABBIT BONE MARROW MESENCHYMAL STEM CELLS FOR OSTEOCHONDRAL DEFECT REPAIR

2015 ◽  
Vol 77 (25) ◽  
Author(s):  
Rozlin Abdul Rahman ◽  
Norhamiza Mohamad Sukri ◽  
Noorhidayah Md Nazir ◽  
Muhammad Aa’zamuddin Ahmad Radzi ◽  
Ahmad Hafiz Zulkifly ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Glycolic Acid ◽  
Osteochondral Defect ◽  
Rabbit Model ◽  
Three Dimensional ◽  
Marker Genes ◽  
Repair Capacity ◽  
Marrow Mesenchymal Stem Cells

Articular cartilage has poor repair capacity due to its avascular and aneural properties and has relatively few cells. This study investigated the ability of autologous implantation approach using three dimensional (3D) constructs engineered from bone marrow mesenchymal stem cells (BMSCs) seeded on poly(lactic-co-glycolic acid) (PLGA) with or without fibrin as cells carrier for the repair of osteochondral defect in rabbit model. The engineered 3D constructs – PLGA/Fibrin/BMSCs and PLGA/BMSCs – were cultured for 3 weeks in vitro and implanted autologously to the osteochondral defect created in the rabbit knee. The in vivo constructs were harvested and evaluated by means of gross observation, histology assessment, gene expression study, sulphated glycosaminoglycan (sGAG) production assay and biomechanical evaluation at 6 and 12 weeks post implantation. The results showed that the osteochondral defects treated with the PLGA/Fibrin/BMSCs constructs exhibited better repairment, more cartilaginous extracellular matrix, higher sGAG production, superior compressive strength and more intense expression of chondrogenic marker genes than the PLGA/BMSCs group. This study suggested that the PLGA/Fibrin/BMSCs has the potential to treat osteochondral defect and may be presented as a viable therapeutic option for those who would be in need from the life-extending benefits of tissue replacement or repair.

Mechanical stimulations on human bone marrow mesenchymal stem cells enhance cells differentiation in a three‐dimensional layered scaffold

2017 ◽  
Vol 12 (2) ◽  
pp. 360-369 ◽  
Author(s):  
Jessica Schiavi ◽  
Loïc Reppel ◽  
Naceur Charif ◽  
Natalia Isla ◽  
Didier Mainard ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Three Dimensional ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Marrow Mesenchymal Stem Cells

scholarly journals 520 CHONDROGENIC POTENTIALITY OF HYPOXIA ON HUMAN BONE MARROW MESENCHYMAL STEM CELLS IN THREE DIMENSIONAL CULTURE

2010 ◽  
Vol 18 ◽  
pp. S233
Author(s):  
C. Henrionnet ◽  
G. Liang ◽  
L. Galois ◽  
D. Mainard ◽  
D. Bensoussan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Three Dimensional ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Marrow Mesenchymal Stem Cells ◽  
Three Dimensional Culture
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