Bone augmentation by bone marrow mesenchymal stem cells cultured in three-dimensional biodegradable polymer scaffolds

2009 ◽  
Vol 91A (2) ◽  
pp. 428-435 ◽  
Author(s):  
Toshimitsu Tanaka ◽  
Motohiro Hirose ◽  
Noriko Kotobuki ◽  
Mika Tadokoro ◽  
Hajime Ohgushi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Biodegradable Polymer ◽  
Three Dimensional ◽  
Bone Augmentation ◽  
Polymer Scaffolds ◽  
Marrow Mesenchymal Stem Cells ◽  
Cells Cultured

An Experimental Study Comparing the Expansion of Peripheral Blood Natural Killer (NK) Cells Cultured with Artificial Antigen-Presenting Cells, in the Presence or Absence of Bone Marrow Mesenchymal Stem Cells (MSCs)

2020 ◽  
Vol 62 (5) ◽  
pp. 306-315
Author(s):  
Jaiza Frias Pedroso ◽  
Vanessa de Souza Valim ◽  
Annelise Pezzi ◽  
Juliana Monteiro Furlan ◽  
Gabriele Lenhart ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Experimental Study ◽  
Mesenchymal Stem Cells ◽  
Natural Killer ◽  
Peripheral Blood ◽  
Artificial Antigen ◽  
Marrow Mesenchymal Stem Cells ◽  
Antigen Presenting ◽  
Cells Cultured

k-Casein upregulates osteogenic differentiation on bone marrow mesenchymal stem cells cultured on agarose microcarriers

2019 ◽  
Vol 69 (6) ◽  
pp. 373-380 ◽  
Author(s):  
Hammed Tanimowo Aiyelabegan ◽  
Malihe Ebadi ◽  
Gholam Ali Kardar ◽  
Nasrin Lotfibakhshaiesh ◽  
Farid Abedin Dorkoosh ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Osteogenic Differentiation ◽  
Marrow Mesenchymal Stem Cells ◽  
Cells Cultured

Different combinations of growth factors for the tenogenic differentiation of bone marrow mesenchymal stem cells in monolayer culture and in fibrin-based three-dimensional constructs

2017 ◽  
Vol 95 ◽  
pp. 44-53 ◽  
Author(s):  
Marta Bottagisio ◽  
Silvia Lopa ◽  
Valentina Granata ◽  
Giuseppe Talò ◽  
Chiara Bazzocchi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Growth Factors ◽  
Monolayer Culture ◽  
Three Dimensional ◽  
Tenogenic Differentiation ◽  
Marrow Mesenchymal Stem Cells

scholarly journals Effect of temporally patterned TNF-α delivery on in vitro osteogenic differentiation of mesenchymal stem cells cultured on biodegradable polymer scaffolds

2013 ◽  
Vol 24 (15) ◽  
pp. 1794-1813 ◽  
Author(s):  
Paschalia M. Mountziaris ◽  
E. Dennis Lehman ◽  
Ioannis Mountziaris ◽  
David C. Sing ◽  
F. Kurtis Kasper ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Osteogenic Differentiation ◽  
Biodegradable Polymer ◽  
Polymer Scaffolds ◽  
Tnf Α ◽  
Cells Cultured

scholarly journals Character of Spreading and Cytoskeleton Structure of Bone Marrow Mesenchymal Stem Cells Cultured on Chitosan Scaffolds

2016 ◽  
Vol 26 (2) ◽  
pp. 173-173
Author(s):  
A. V. Kisil ◽  
◽  
V. V. Kiroshka ◽  
Tatyana P. Bondarenko ◽  
V. A. Petrova ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Marrow Mesenchymal Stem Cells ◽  
Chitosan Scaffolds ◽  
Cells Cultured

scholarly journals Three-dimensional spheroid culture of canine hepatocyte-like cells derived from bone marrow mesenchymal stem cells

2020 ◽  
Vol 15 ◽  
pp. 210-215
Author(s):  
Suguru Nitta ◽  
Masaharu Hisasue ◽  
Yu Horiguchi ◽  
Yoko Yamada ◽  
Kaoruko Kikuchi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Three Dimensional ◽  
Spheroid Culture ◽  
Marrow Mesenchymal Stem Cells

EVALUATION OF THREE DIMENSIONAL CONSTRUCT ENGINEERED FROM POLY(LACTIC-CO-GLYCOLIC ACID)/FIBRIN HYBRID SCAFFOLD USING RABBIT BONE MARROW MESENCHYMAL STEM CELLS FOR OSTEOCHONDRAL DEFECT REPAIR

2015 ◽  
Vol 77 (25) ◽  
Author(s):  
Rozlin Abdul Rahman ◽  
Norhamiza Mohamad Sukri ◽  
Noorhidayah Md Nazir ◽  
Muhammad Aa’zamuddin Ahmad Radzi ◽  
Ahmad Hafiz Zulkifly ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Glycolic Acid ◽  
Osteochondral Defect ◽  
Rabbit Model ◽  
Three Dimensional ◽  
Marker Genes ◽  
Repair Capacity ◽  
Marrow Mesenchymal Stem Cells

Articular cartilage has poor repair capacity due to its avascular and aneural properties and has relatively few cells. This study investigated the ability of autologous implantation approach using three dimensional (3D) constructs engineered from bone marrow mesenchymal stem cells (BMSCs) seeded on poly(lactic-co-glycolic acid) (PLGA) with or without fibrin as cells carrier for the repair of osteochondral defect in rabbit model. The engineered 3D constructs – PLGA/Fibrin/BMSCs and PLGA/BMSCs – were cultured for 3 weeks in vitro and implanted autologously to the osteochondral defect created in the rabbit knee. The in vivo constructs were harvested and evaluated by means of gross observation, histology assessment, gene expression study, sulphated glycosaminoglycan (sGAG) production assay and biomechanical evaluation at 6 and 12 weeks post implantation. The results showed that the osteochondral defects treated with the PLGA/Fibrin/BMSCs constructs exhibited better repairment, more cartilaginous extracellular matrix, higher sGAG production, superior compressive strength and more intense expression of chondrogenic marker genes than the PLGA/BMSCs group. This study suggested that the PLGA/Fibrin/BMSCs has the potential to treat osteochondral defect and may be presented as a viable therapeutic option for those who would be in need from the life-extending benefits of tissue replacement or repair.

The process of heme synthesis in bone marrow mesenchymal stem cells cultured with fibroblast growth factor bFGF and under hypoxic conditions

BIOPHYSICS ◽  
2014 ◽  
Vol 59 (6) ◽  
pp. 913-917 ◽  
Author(s):  
A. G. Poleshko ◽  
E. S. Lobanok ◽  
L. M. Mezhevikina ◽  
E. E. Fesenko ◽  
I. D. Volotovski
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth ◽  
Heme Synthesis ◽  
Hypoxic Conditions ◽  
Marrow Mesenchymal Stem Cells ◽  
Cells Cultured

Mechanical stimulations on human bone marrow mesenchymal stem cells enhance cells differentiation in a three‐dimensional layered scaffold

2017 ◽  
Vol 12 (2) ◽  
pp. 360-369 ◽  
Author(s):  
Jessica Schiavi ◽  
Loïc Reppel ◽  
Naceur Charif ◽  
Natalia Isla ◽  
Didier Mainard ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Three Dimensional ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Marrow Mesenchymal Stem Cells
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