scholarly journals Clinical manifestations and epigenetic mechanisms of gastric mucosa associated lymphoid tissue lymphoma and long‑term follow‑up following Helicobacter�pylori eradication

Author(s):  
Yan Song ◽  
Kui Jiang ◽  
Shuai Su ◽  
Bangmao Wang ◽  
Guangxia Chen
2020 ◽  
Vol 52 (11) ◽  
pp. 1365-1366
Author(s):  
Yang-Yuan Chen ◽  
Yung-Fang Chen ◽  
Chih-Hsuan Chen

2019 ◽  
Vol 98 (7) ◽  
pp. 1675-1687 ◽  
Author(s):  
Kosuke Toyoda ◽  
Akiko Miyagi Maeshima ◽  
Junko Nomoto ◽  
Tomotaka Suzuki ◽  
Sayako Yuda ◽  
...  

2008 ◽  
Vol 247 (2) ◽  
pp. 265-269 ◽  
Author(s):  
Sung-Hsin Kuo ◽  
Li-Tzong Chen ◽  
Ming-Shiang Wu ◽  
Chung-Wu Lin ◽  
Kun-Huei Yeh ◽  
...  

2012 ◽  
Vol 33 (5) ◽  
pp. 775-781 ◽  
Author(s):  
Shinichi Takatsuki ◽  
Jeffrey R. Darst ◽  
Bibhuti B. Das ◽  
Thomas E. Fagan ◽  
Robert Wolfe ◽  
...  

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
F. Molinaro ◽  
R. Angotti ◽  
E. Bindi ◽  
M. Sica ◽  
M. Aglianò ◽  
...  

<em>Introduction</em>: Hypospadias is one of the most common birth defects that affect the male urogenital tract. It can present as isolated anomaly, but sometimes can arise in the context of complex disorders of sex development (DSD). These malformations are characterized by a great variety of clinical manifestations and compromise the aesthetic appearance, but also functional and psychological impact that the malformation can determine the patient. <br /><em>Materials and Methods</em>: We conducted a retrospective study of patients undergoing surgery for hypospadias from March 2000 to January 2015. The data was extrapolated from a prospective database. It was considered for each patient: demographics; type of hypospadias; surgical technique; average age for surgery; intraoperative and postoperative complications (early and late). Duckett’s classification was used. <br /><em>Results</em>: 343 urethroplasties were performed. 320 (93%) were primary urethroplasties and 23 (7%) reoperations in patients who had performed many other surgical procedures. 7 patients with megameatus were excluded. The hypospadias have been ranked according to Duckett’s classification, 35 patients had associated diseases. In total were performed: 186 (55%) Snodgrass, 71(21%) Duckett,10 (3%) augmented Duckett, 42 (13%) Magpi, 16 (5%) Duplay, 1 (0,3%) Bracka, 1 (0,3%) was a Bianchi’technique and 5 (1,4%) were Standoli. In 4 patients (1%) were used mixed technique. There were no intraoperative complications. The mean age at surgery was 15 months (range 12-22 months). Postoperative complications were 12%. Long term follow up was done with uroflussimetrie at 3 and 6 months in those who had reached the continence and possible urethral calibrations in those who had submitted a stenosis in post-op.<br /><em>Conclusions</em>: The improvement of surgical techniques, the use of optical amplification tools, the use of suture material (PDS) and the experience gained in recent years have enabled us to optimized the results. Though aware of the potential and actual complications that this type of microsurgical correction can lead to the results we have obtained are comparable to those of major international series and can be considered satisfactory, both from an aesthetic and functional.


2017 ◽  
Vol 58 (4) ◽  
pp. 537-542 ◽  
Author(s):  
Yu Ohkubo ◽  
Yoshihiro Saito ◽  
Hiroki Ushijima ◽  
Masahiro Onishi ◽  
Tomoko Kazumoto ◽  
...  

Abstract This study aimed to assess the long-term outcomes of radiotherapy in patients with localized gastric mucosa–associated lymphoid tissue (MALT) lymphoma. Twenty-seven patients with Stage I gastric MALT lymphoma were treated with radiotherapy from 1999 to 2010. The median age was 65 years (range: 31–84). Fifteen patients were Helicobacter pylori–negative. Thirteen patients were treated with definitive radiotherapy alone. The other 14 patients who had refractory or residual disease following a prior treatment received salvage radiotherapy. The median dose of the radiotherapy was 30 Gy in 20 fractions (range: 30–39.5 Gy). The median follow-up period was 121 months (range: 8–176 months). The 5- and 10-year overall survival rates for all patients were 92% and 87%, respectively. No patients died from MALT lymphoma. Three patients died of other diseases at 8, 33 and 74 months after radiotherapy (myocardial infarction, pneumonia and hepatocellular carcinoma, respectively). No cases of local recurrence were observed during the follow-up period. There were no serious late gastric, liver or kidney complications during a median follow-up period of over 10 years. Two patients remain alive with distant metastases: a lung metastasis and an abdominal lymph node metastasis at 104 months and 21 months after radiotherapy, respectively. Excellent long-term local control was observed in patients with localized gastric MALT lymphoma after radiotherapy. However, lifelong follow-up should be conducted to detect cases of late recurrence, especially distant metastases.


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