scholarly journals Place of bronchoscopy in the diagnostics and follow-up of patients with idiopathic pulmonary hemosiderosis

Folia Medica ◽  
2021 ◽  
Vol 63 (4) ◽  
pp. 582-585
Author(s):  
Ivanka P. Karavelikova

The idiopathic pulmonary hemosiderosis is a rare, life-threatening condition observed mainly in children and characterized by recurrent episodes of diffuse alveolar hemorrhages. The disease is characterized by the triad of hemoptysis, alveolar infiltrates in chest radiography, and iron-deficiency anemia. The recurrent episodes of alveolar hemorrhage can lead to chronic iron-deficiency anemia and irreversible pulmonary fibrosis; therefore, early diagnosis and treatment are crucial to the outcome of the disease.The idiopathic pulmonary hemosiderosis is a rare, life-threatening condition observed mainly in children and characterized by recurrent episodes of diffuse alveolar hemorrhages. The disease is characterized by the triad of hemoptysis, alveolar infiltrates in chest radiography, and iron-deficiency anemia. The recurrent episodes of alveolar hemorrhage can lead to chronic iron-deficiency anemia and irreversible pulmonary fibrosis; therefore, early diagnosis and treatment are crucial to the outcome of the disease.

2010 ◽  
Vol 68 ◽  
pp. 640-641
Author(s):  
S Corujeira ◽  
R Santos-Silva ◽  
F Ferreira ◽  
C Rego ◽  
A Maia ◽  
...  

2017 ◽  
Vol 9 (2) ◽  
Author(s):  
Sultan Aydin Koker ◽  
Salih Gözmen ◽  
Yeşim Oymak ◽  
Tuba Hilkay Karapinar ◽  
Demet Can ◽  
...  

Idiopathic pulmonary hemosiderosis (IPH) is an uncommon chronic disorder in children. It is characterized by recurrent pulmonary hemorrhage and may result in hemoptysis and pulmonary insufficiency. The most common hematologic manifestation of IPH is iron deficiency anemia. The etiology of IPH is not known and its diagnosis may be difficult due to the variable clinical courses. The most helpful signs for identifying IPH are iron deficiency anemia and recurrent or chronic cough, hemoptysis, dyspnea, wheezing. We report here 5 pediatric cases of IPH presenting with iron deficiency anemia and without pulmonary symptoms. Mean corpuscular volume was low in all patients; iron was low in 4 out of 5 cases; total iron binding capacity was high in all of them; ferritin was low in 3 patients. At follow up, none of them had responded successfully to the iron therapy. Although they didn’t present with pulmonary symptoms, chest radiographs incidentally revealed diffuse reticulonoduler shadows in all of them. Computed tomography revealed diffuse ground-glass opacities, consolidation, increased density. The diagnosis was confirmed by the detection of hemosiderinladen macrophages in bronchoalveolar lavage fluid and gastric aspirate. If patients with iron deficiency anemia don’t respond to iron therapy, they should be examined for IPH. Chest radiographs should be taken even in absence of pulmonary symptoms. Early diagnosis is important for a timely management of IPH.


2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
A. Potalivo ◽  
L. Finessi ◽  
F. Facondini ◽  
A. Lupo ◽  
C. Andreoni ◽  
...  

Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of alveolar hemorrhage in children but should be considered in children with anemia of unknown origin who develop respiratory complications. It is commonly characterized by the triad of recurrent hemoptysis, diffuse parenchymal infiltrates, and iron-deficiency anemia. Pathogenesis is unclear and diagnosis may be difficult along with a variable clinical course. A 6-year-old boy was admitted to the hospital with a severe iron-deficiency anemia, but he later developed severe acute respiratory failure and hemoptysis requiring intubation and mechanical ventilation. The suspicion of IPH led to the use of immunosuppressive therapy with high dose of corticosteroids with rapid improvement in clinical condition and discharge from hospital.


CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 922A
Author(s):  
Jeffrey Chen ◽  
Antonio Bonet ◽  
Scott Oh ◽  
G. Pezeshkpour ◽  
Guy Soo Hoo

Author(s):  
Anjuna Reghunath ◽  
Joyutpal Biswas ◽  
Mahesh Kumar Mittal ◽  
Reeta Kanaujiya ◽  
Geetika Khanna

AbstractIdiopathic pulmonary hemosiderosis (IPH) is an unusual cause of pediatric iron deficiency anemia (IDA) characterized by alveolar hemorrhage leading to hemosiderin deposition and fibrosis in the lungs. Though the typical triad of presentation is hemoptysis, IDA, and lung opacities on thoracic radiographs, often the sole manifestation of IPH may be severe IDA in children.


Cureus ◽  
2021 ◽  
Author(s):  
Abdulrahman M Alateeq ◽  
Hessa A Alshammari ◽  
Abdulmalik M Alsaif

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