scholarly journals Light and scanning electron microscopic examination of the Saanen goat heart

2020 ◽  
Vol 44 (6) ◽  
pp. 1172-1180
Author(s):  
Sedef SELVİLER SİZER ◽  
Yonca Betil KABAK ◽  
Murat KABAK
Keyword(s):  
Microscopic Examination ◽  
Electron Microscopic Examination ◽  
Electron Microscopic ◽  
Saanen Goat ◽  
Scanning Electron Microscopic ◽  
Scanning Electron

Developmental Disturbances of the Rat Molar Induced By Two Diphosphonates

1989 ◽  
Vol 3 (2) ◽  
pp. 234-240 ◽  
Author(s):  
N. Fouda ◽  
M. Caracatsanis ◽  
L. Hammarstrom
Keyword(s):  
Microscopic Examination ◽  
Alveolar Bone ◽  
Morphological Changes ◽  
Electron Microscopic Examination ◽  
Enamel Matrix ◽  
Electron Microscopic ◽  
Developmental Disturbances ◽  
Scanning Electron Microscopic ◽  
Rat Molar ◽  
Scanning Electron

Very few reports have been published about the effects of diphosphonates on the cells and tissues of developing teeth. The present study was designed to investigate possible morphological changes in ameloblasts and odontoblasts and relate these changes to defects in the enamel surface of erupted teeth. Young rats were injected subcutaneously with single or multiple doses of HEDP or Cl2MDP (10 mg P/kg b.w.). Light microscopic examination of developing maxillary first molars showed that single injections of HEDP or Cl2MDP induced subameloblastic cysts between the secretory ameloblasts and the developing enamel. The ameloblastic lining of the cysts contained numerous calcified deposits. A few days after injection, hypoplasias were seen in the enamel in areas previously occupied by cysts. In the erupted teeth, scanning electron microscopic examination revealed enamel hypoplasias which were mainly localized on the mesial sides of the cusps. In addition to the previously mentioned disturbances, multiple injections resulted in more extensive cysts, some of which contained non-mineralized enamel matrix. Inhibition of the mineralization of dentin and alveolar bone was also noticed.

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