Low-Dose Intraoperative Mitomycin-C Versus Conjunctival Autograft in Primary Pterygium Surgery: Long Term Follow-Up

AIM: To evaluate the safety and efficacy of limbal conjunctival autograft transplantation for treating primary pterygium over a period of 3y. METHODS: Prospective observational consecutive case series. In this study, 264 eyes of 264 patients (142 males and 122 females) with nasal primary pterygium were treated using the technique of limbal conjunctival autograft. The mean ages of the patients were 54.22±15.24y. After excision of the pterygium patients were followed up on 1, 3, 7d and at 1, 3, 6, 9, 12, and 36mo. Recurrence of pterygium, complications, operation time and corneal epithelialization time were evaluated. RESULTS: The average surgery time was 25.7±2.6min. With a minimum 3-year of follow-up, postoperative corneal epithelialization was completed in 3.85±0.72d. Complications were observed in 14 cases. Vision-threating complications such as iritis, scleral thinning symblepharon or ulceration were not detected in the study. Five eyes with graft edema, 3 eyes with granuloma formation and 6 cases with a subconjunctival hematoma in the nasal conjunctiva. By the end of 3-year follow-up, recurrence was detected in 11 cases. The recurrence rate was 4.17%, and the onset of recurrence was 3mo, the average recurrence time was 8mo. CONCLUSION: There were no severe complications and few recurrences when limbal conjunctival autograft transplantation was performed after long-term follow-up, we suggest that limbal conjunctival autograft transplantation is a safe and effective technique in primary pterygium. We also recommend that 12-month follow-up is optimal on primary pterygium surgery.

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Long-Term Follow-Up of Pterygium Surgery Using a Conjunctival Autograft and Tissucol

Cornea ◽

10.1097/ico.0b013e3181dea7f0 ◽

2011 ◽

Vol 30 (1) ◽

pp. 34-36 ◽

Cited By ~ 12

Author(s):

Carla P Nieuwendaal ◽

Ivanka J E van der Meulen ◽

Maarten Mourits ◽

Ruthie Lapid-Gortzak

Keyword(s):

Conjunctival Autograft ◽

Long Term Follow Up ◽

Pterygium Surgery

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A comparative evaluation of conjunctival autograft and intra- operative mitomycin-C in the management of primary pterygium- our experience

International Surgery Journal ◽

10.18203/2349-2902.isj20171617 ◽

2017 ◽

Vol 4 (6) ◽

pp. 1866

Author(s):

Satish D. Shet ◽

Piyush S. Gupta

Keyword(s):

Mitomycin C ◽

Tertiary Care ◽

Care Hospital ◽

Recurrence Rates ◽

Tropical Country ◽

Conjunctival Autograft ◽

Pterygium Surgery ◽

Comparative Prospective Study ◽

Primary Pterygium

Background: Surgery is the treatment of choice in the management of primary pterygium. Recurrence following excision is frustrating to both the surgeons and patients alike. India being a tropical country is an ideal home for pterygium.Methods: This study was carried out in a tertiary care hospital. A comparative prospective study was performed in 80 patients presenting with primary pterygium who fulfill inclusion and exclusion criteria were taken for the study for the period from January 2011 to December 2012. They were randomised in two equal groups to undergo primary pterygium surgery with conjunctival autograft and excision of primary pterygium followed by intraoperative use of Mitomycin-C for 3 minutes to study the effectiveness of adjuncts i.e. mitomycin -C and conjunctival autograft in preventing recurrence of pterygium after excision and complications following the procedure. Follow up visits were scheduled for the postoperative days 1, 7, 30 days and 3 and 6 months. mean follow up was for 9 months.Results: No significant intra operative complications were noted except for 2 cases of button holing of the conjunctival graft. Recurrence was noted in 1 case after conjunctival autograft and 1 case in mitomycin C group.Conclusions: The adjuncts in primary pterygium surgery as conjunctival autograft and pterygium excision with mitomycin-C significantly reduces the recurrence rates than bare sclera excision alone.

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