scholarly journals On symmetric division deg index of trees with given parameters

2021 ◽  
Vol 6 (6) ◽  
pp. 6528-6541
Author(s):  
Jianwei Du ◽  
◽  
Xiaoling Sun
Keyword(s):  
Symmetric Division

scholarly journals Symmetric Division and Expression of Its Regulatory Gene Numb in Human Cervical Squamous Carcinoma Cells

Pathobiology ◽  
2009 ◽  
Vol 76 (3) ◽  
pp. 149-154 ◽  
Author(s):  
Huaizeng Chen ◽  
Xiaojun Chen ◽  
Feng Ye ◽  
Weiguo Lu ◽  
Xing Xie
Keyword(s):  
Regulatory Gene ◽  
Squamous Carcinoma ◽  
Carcinoma Cells ◽  
Symmetric Division ◽  
Squamous Carcinoma Cells

scholarly journals Nano Let-7b sensitization of eliminating esophageal cancer stem-like cells is dependent on blockade of Wnt activation of symmetric division

2017 ◽  
Vol 51 (4) ◽  
pp. 1077-1088 ◽  
Author(s):  
Yamei Pang ◽  
Jian Liu ◽  
Xiang Li ◽  
Yiwen Zhang ◽  
Boxiang Zhang ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Symmetric Division

New results on symmetric division deg index

2020 ◽  
Author(s):  
Modjtaba Ghorbani ◽  
Samaneh Zangi ◽  
Najaf Amraei
Keyword(s):  
Symmetric Division

scholarly journals Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells

2018 ◽  
Vol 116 (2) ◽  
pp. 625-630 ◽  
Author(s):  
Kana Tominaga ◽  
Hiroshi Minato ◽  
Takahiko Murayama ◽  
Asako Sasahara ◽  
Tatsunori Nishimura ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Molecular Mechanisms ◽  
Breast Cancer Patients ◽  
Asymmetric Cell Divisions ◽  
Symmetric Division ◽  
Cell Divisions ◽  
Tumor Sphere ◽  
Neuropilin 1 ◽  
Niche Factor ◽  
Sphere Formation

Cancer stem-like cells (CSCs) are expanded in the CSC niche by increased frequency of symmetric cell divisions at the expense of asymmetric cell divisions. The symmetric division of CSCs is important for the malignant properties of cancer; however, underlying molecular mechanisms remain largely elusive. Here, we show a cytokine, semaphorin 3 (Sema3), produced from the CSC niche, induces symmetric divisions of CSCs to expand the CSC population. Our findings indicate that stimulation with Sema3 induced sphere formation in breast cancer cells through neuropilin 1 (NP1) receptor that was specifically expressed in breast CSCs (BCSCs). Knockdown of MICAL3, a cytoplasmic Sema3 signal transducer, greatly decreased tumor sphere formation and tumor-initiating activity. Mechanistically, Sema3 induced interaction among MICAL3, collapsin response mediator protein 2 (CRMP2), and Numb. It appears that activity of MICAL3 monooxygenase (MO) stimulated by Sema3 is required for tumor sphere formation, interaction between CRMP2 and Numb, and accumulation of Numb protein. We found that knockdown of CRMP2 or Numb significantly decreased tumor sphere formation. Moreover, MICAL3 knockdown significantly decreased Sema3-induced symmetric divisions in NP1/Numb-positive BCSCs and increased asymmetric division that produces NP1/Numb negative cells without stem-like properties. In addition, breast cancer patients with NP1-positive cancer tissues show poor prognosis. Therefore, the niche factor Sema3-stimulated NP1/MICAL3/CRMP2/Numb axis appears to expand CSCs at least partly through increased frequency of MICAL3-mediated symmetric division of CSCs.

scholarly journals Valency-based molecular descriptors of Bakelite network BNmn$B\text N_{m}^{n}$

2019 ◽  
Vol 17 (1) ◽  
pp. 663-670 ◽  
Author(s):  
Maqsood Ahmad ◽  
Muhammad Javaid ◽  
Muhammad Saeed ◽  
Chahn Yong Jung
Keyword(s):  
Physical Properties ◽  
Molecular Descriptors ◽  
Molecular Graph ◽  
Synthetic Polymer ◽  
Topological Indices ◽  
Qsar Studies ◽  
Zagreb Indices ◽  
Symmetric Division ◽  
Atom Bond

AbstractBakelite network $BN_{m}^{n}$is a molecular graph of bakelite, a pioneering and revolutionary synthetic polymer (Thermosetting Plastic) and regarded as the material of a thousand uses. In this paper, we aim to compute various degree-based topological indices of a molecular graph of bakelite network $BN_{m}^{n}$. These molecular descriptors play a fundamental role in QSPR/QSAR studies in describing the chemical and physical properties of Bakelite network $BN_{m}^{n}$. We computed atom-bond connectivity ABC its fourth version ABC4 geometric arithmetic GA its fifth version GA5 Narumi-Katayama, sum-connectivity and Sanskruti indices, first, second, modified and augmented Zagreb indices, inverse and general Randic’ indices, symmetric division, harmonic and inverse sum indices of $BN_{m}^{n}$.

Spindle in position for symmetric division

2012 ◽  
Vol 13 (5) ◽  
pp. 278-279
Author(s):  
Maria Papatriantafyllou
Keyword(s):  
Symmetric Division
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