<b>Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of Macitentan, a New Endothelin Receptor Antagonist, in Healthy Japanese Male Subjects </b>

Endothelin Receptor ◽

Japanese Male ◽

Japanese Male Subjects ◽

Clinical Pharmacokinetics and Pharmacodynamics of the Endothelin Receptor Antagonist Macitentan

Clinical Pharmacokinetics ◽

10.1007/s40262-015-0255-5 ◽

2015 ◽

Vol 54 (5) ◽

pp. 457-471 ◽

Cited By ~ 21

Author(s):

P. N. Sidharta ◽

A. Treiber ◽

J. Dingemanse

Keyword(s):

Receptor Antagonist ◽

Endothelin Receptor ◽

Clinical Pharmacokinetics

Pharmacokinetics and pharmacodynamics of tezosentan, an intravenous dual endothelin receptor antagonist, following chronic infusion in healthy subjects

British Journal of Clinical Pharmacology ◽

10.1046/j.1365-2125.2002.01158.x ◽

2002 ◽

Vol 53 (4) ◽

pp. 355-362 ◽

Cited By ~ 26

Author(s):

Jasper Dingemanse ◽

Martine Clozel ◽

Paul L. M. Van Giersbergen

Keyword(s):

Receptor Antagonist ◽

Healthy Subjects ◽

Endothelin Receptor ◽

Chronic Infusion

Pharmacokinetics and pharmacodynamics of the endothelin-receptor antagonist bosentan in healthy human subjects

Clinical Pharmacology & Therapeutics ◽

10.1016/s0009-9236(96)90127-7 ◽

1996 ◽

Vol 60 (2) ◽

pp. 124-137 ◽

Cited By ~ 158

Author(s):

Cornelia Weber ◽

Rita Schmitt ◽

Herbert Birnboeck ◽

Gerard Hopfgartner ◽

Sjoerd P. van Marle ◽

...

Keyword(s):

Receptor Antagonist ◽

Human Subjects ◽

Endothelin Receptor ◽

Healthy Human ◽

Healthy Human Subjects

Safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple doses of apixaban in healthy Japanese male subjects

International Journal of Clinical Pharmacology and Therapeutics ◽

10.5414/cp201967 ◽

2014 ◽

Cited By ~ 3

Author(s):

Naomi Yamahira ◽

Charles Frost ◽

Hiroyuki Fukase ◽

Zhigang Yu ◽

Jessie Wang ◽

...

Keyword(s):

Multiple Doses ◽

Japanese Male ◽

Japanese Male Subjects ◽

Safety, tolerability, pharmacokinetics, and pharmacodynamics of macitentan, an endothelin receptor antagonist, in an ascending multiple-dose study in healthy subjects

The Journal of Clinical Pharmacology ◽

10.1002/jcph.152 ◽

2013 ◽

pp. n/a-n/a ◽

Cited By ~ 15

Author(s):

Patricia N. Sidharta ◽

Paul L. M. van Giersbergen ◽

Jasper Dingemanse

Keyword(s):

Receptor Antagonist ◽

Healthy Subjects ◽

Multiple Dose ◽

Endothelin Receptor ◽

Multiple Dose Study ◽

Dose Study

Effect of the Endothelin-Receptor Antagonist Bosentan on the Pharmacokinetics and Pharmacodynamics of Warfarin

The Journal of Clinical Pharmacology ◽

10.1177/00912709922008380 ◽

1999 ◽

Vol 39 (8) ◽

pp. 847-854 ◽

Cited By ~ 57

Author(s):

Cornelia Weber ◽

Ludger Banken ◽

Herbert Birnboeck ◽

Rainer Schulz

Keyword(s):

Receptor Antagonist ◽

Pharmacokinetics And Pharmacodynamics

Endothelin Receptor ◽

Pharmacokinetics and pharmacodynamics of single-dose oral tolvaptan in fasted and non-fasted states in healthy Caucasian and Japanese male subjects

European Journal of Clinical Pharmacology ◽

10.1007/s00228-012-1295-5 ◽

2012 ◽

Vol 68 (12) ◽

pp. 1595-1603 ◽

Cited By ~ 23

Author(s):

Susan E. Shoaf ◽

Seong Ryul Kim ◽

Patricia Bricmont ◽

Suresh Mallikaarjun

Keyword(s):

Single Dose ◽

Japanese Male ◽

Dose Oral ◽

Japanese Male Subjects ◽

Single- and multiple-dose tolerability, safety, pharmacokinetics, and pharmacodynamics of the dual endothelin receptor antagonist aprocitentan in healthy adult and elderly subjects

Drug Design Development and Therapy ◽

10.2147/dddt.s199051 ◽

2019 ◽

Vol Volume 13 ◽

pp. 949-964 ◽

Cited By ~ 9

Author(s):

Patricia Sidharta ◽

Meggane Melchior ◽

Martin K. Kankam ◽

Jasper Dingemanse

Keyword(s):

Receptor Antagonist ◽

Multiple Dose ◽

Healthy Adult ◽

Pharmacokinetics And Pharmacodynamics

Elderly Subjects ◽

Endothelin Receptor ◽

Tolerability, pharmacokinetics, and pharmacodynamics of clazosentan, a parenteral endothelin receptor antagonist

European Journal of Clinical Pharmacology ◽

10.1007/s00228-006-0117-z ◽

2006 ◽

Vol 63 (2) ◽

pp. 151-158 ◽

Cited By ~ 19

Author(s):

Paul L. M. van Giersbergen ◽

Jasper Dingemanse

Keyword(s):

Receptor Antagonist ◽

Pharmacokinetics And Pharmacodynamics

Endothelin Receptor ◽

Pharmacokinetics and pharmacodynamics of mepolizumab, an anti–interleukin 5 monoclonal antibody, in healthy Japanese male subjects

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.205 ◽

2015 ◽

Vol 5 (2) ◽

pp. 102-108 ◽

Cited By ~ 12

Author(s):

Naohiro Tsukamoto ◽

Naoki Takahashi ◽

Hiroshi Itoh ◽

Isabelle Pouliquen

Keyword(s):

Monoclonal Antibody ◽

Interleukin 5 ◽

Japanese Male ◽

Japanese Male Subjects ◽