Osteogenic Effect of Genistein on In Vitro Bone Formation by Human Bone Marrow Cell Culture - For Development of Advanced Bio-Artificial Bone

2005 ◽  
pp. 667-670
Author(s):  
Noriko Okumura ◽  
Takafumi Yoshikawa ◽  
Jin Iida ◽  
Akitaka Nonomura ◽  
Yoshinori Takakura
Keyword(s):  
Cell Culture ◽  
Bone Marrow ◽  
Bone Formation ◽  
Marrow Cell ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Human Bone Marrow Cell ◽  
Osteogenic Effect ◽  
Bone Marrow Cell Culture

Human Bone Marrow Cell Culture: A Sensitive Method for Determination of the Biocompatibility of Implant Materials

1999 ◽  
Vol 27 (1) ◽  
pp. 137-151 ◽  
Author(s):  
Axel Wilke ◽  
Maximilian Landgraff ◽  
Joachim Orth ◽  
Holger Poenitz ◽  
Heino Kienapfel ◽  
...  
Keyword(s):  
Cell Culture ◽  
Bone Marrow ◽  
Bone Marrow Cell ◽  
Marrow Cell ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Human Bone Marrow Cell ◽  
Bone Marrow Cell Culture ◽  
Sensitive Method

Osteogenic Effect of Genistein on In Vitro Bone Formation by Human Bone Marrow Cell Culture - For Development of Advanced Bio-Artificial Bone

2005 ◽  
Vol 284-286 ◽  
pp. 667-670 ◽  
Author(s):  
Noriko Okumura ◽  
Takafumi Yoshikawa ◽  
Jin Iida ◽  
Akitaka Nonomura ◽  
Yoshinori Takakura
Keyword(s):  
Bone Marrow ◽  
Bone Formation ◽  
Bone Marrow Cells ◽  
Marrow Cell ◽  
Calf Serum ◽  
New Bone Formation ◽  
Human Bone Marrow Cell ◽  
Osteogenic Effect ◽  
Marrow Cells

The effect of genistein, a soybean isoflavone, on new bone formation by bone marrow cells from mature humans was examined. After informed consent was obtained from a 55-year-old woman with osteoporosis and lumbar spondylosis deformans，bone marrow cells were collected from her ilium, cultured in the standard medium of MEM containing fetal calf serum and then cultured with or without the addition of genistein to the bone-forming medium containing dexamethasone etc.． In humans, when genistein was added to the bone-forming medium, genistein (10-7 M and 10-8 M)caused a significant increase in the levels of alkaline phosphatase avtivity and DNA content compared with cells not cultured in genistein． In conclusion，genistein was found to promote bone formation at lower concentrations，and thus may be useful as a bone formation-promoting factor.

Pore Geometry Regulates Early Stage Human Bone Marrow Cell Tissue Formation and Organisation

2013 ◽  
Vol 41 (5) ◽  
pp. 917-930 ◽  
Author(s):  
J. Knychala ◽  
N. Bouropoulos ◽  
C. J. Catt ◽  
O. L. Katsamenis ◽  
C. P. Please ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cell ◽  
Early Stage ◽  
Marrow Cell ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Pore Geometry ◽  
Tissue Formation ◽  
Cell Tissue ◽  
Human Bone Marrow Cell
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