Cerebral salt wasting syndrome in traumatic brain injury following therapeutic barbiturate coma

2011 ◽  
Vol 153 (8) ◽  
pp. 1719-1720 ◽  
Author(s):  
M. Kontogiorgi ◽  
P. Opsimoulis ◽  
E. Diamanti-Kandarakis ◽  
A. Karabinis
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cerebral Salt Wasting Syndrome ◽  
Barbiturate Coma ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

scholarly journals Cerebral salt wasting syndrome caused by severe traumatic brain injury: pediatric case report and review of the literature

2021 ◽  
Author(s):  
Mohamed Aziz Daghmouri ◽  
Maroua Oueslati ◽  
Mohamed Amine Touati ◽  
Olfa Faten ◽  
Sameh Zakhama ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cerebral Salt Wasting Syndrome ◽  
Pediatric Case ◽  
Cerebral Salt Wasting ◽  
Adequate Treatment ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Acute Traumatic Brain Injury ◽  
Salt Wasting Syndrome

Following acute traumatic brain injury, cerebral salt wasting (CSW) syndrome is considered as an important cause of hyponatremia apart from syndrome of inappropriate antidiuretic hormone. Differentiation between the two syndromes is crucial for the initiation of an adequate treatment. So we report a pediatric case.

scholarly journals Pengelolaan Diabetes Insipidus dengan Cerebral Salt Wasting Syndrome dan Tension Pneumocephalus pada Pasien Pascabedah Eksisi Tumor Pineal

2021 ◽  
Vol 10 (3) ◽  
pp. 182-192
Author(s):  
Dhania A. Santosa ◽  
◽  
Nancy Margareta Rehatta
Keyword(s):  
Brain Injury ◽  
Diabetes Insipidus ◽  
Pineal Tumor ◽  
Secondary Brain Injury ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Tension Pneumocephalus ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

Electrolyte imbalance is an often incident in patients underwent neurosurgery and it potentially induces secondary brain injury, leading to a worse outcome, despite successful surgery. Diabetes insipidus is a frequent hypernatremic condition, commonly caused by abnormalities in the hypophysis; but rarely happens due to pineal tumor. A 21-year-old male with preoperative diabetes insipidus experienced episodes of diabetes insipidus complicated by cerebral salt wasting syndrome and tension pneumocephalus after a successful pineal tumor removal surgery. Closed observation on volume status, plasma glucose and electrolyte, along with optimal dose of desmopressin were keys of successful postoperative management in this patient in order to avoid the patient from secondary brain injury. An intensivist plays a key role, mainly in the understanding of intracranial pathophysiology and its implications to fluid and electrolyte balance.

scholarly journals Central Neurogenic Diabetes Insipidus, Syndrome of Inappropriate Secretion of Antidiuretic Hormone, and Cerebral Salt-Wasting Syndrome in Traumatic Brain Injury

2012 ◽  
Vol 32 (2) ◽  
pp. e1-e7 ◽  
Author(s):  
Cynthia (Cindi) A. John ◽  
Michael W. Day
Keyword(s):  
Traumatic Brain Injury ◽  
Diabetes Insipidus ◽  
Antidiuretic Hormone ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Inappropriate Secretion ◽  
Salt Wasting Syndrome ◽  
Neurogenic Diabetes Insipidus

Central neurogenic diabetes insipidus, syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome are secondary events that affect patients with traumatic brain injury. All 3 syndromes affect both sodium and water balance; however, they have differences in pathophysiology, diagnosis, and treatment. Differentiating between hypernatremia (central neurogenic diabetes insipidus) and the 2 hyponatremia syndromes (syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome) is critical for preventing worsening neurological outcomes in patients with head injuries.

scholarly journals Cerebral salt wasting syndrome

2016 ◽  
Vol 03 (03) ◽  
pp. 205-210 ◽  
Author(s):  
Harshal Dholke ◽  
Ann Campos ◽  
C. Reddy ◽  
Manas Panigrahi
Keyword(s):  
Brain Injury ◽  
Hormone Secretion ◽  
Sodium Balance ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Adequate Hydration ◽  
Sodium Regulation ◽  
Salt Wasting Syndrome

AbstractTraumatic brain injury (TBI) is on the rise, especially in today’s fast-paced world. TBI requires not only neurosurgical expertise but also neurointensivist involvement for a better outcome. Disturbances of sodium balance are common in patients with brain injury, as the central nervous system plays a major role in sodium regulation. Hyponatraemia, defined as serum sodium <135 meq/L is commonly seen and is especially deleterious as it can contribute to cerebral oedema in these patients. Syndrome of inappropriate antidiuretic hormone secretion (SIADH), is the most well-known cause of hyponatraemia in this subset of patients. Cerebral Salt Wasting Syndrome (CSWS), leading to renal sodium loss is an important cause of hyponatraemia in patients with TBI. Although incompletely studied, decreased renal sympathetic responses and cerebral natriuretic factors play a role in the pathogenesis of CSWS. Maintaining a positive sodium balance and adequate hydration can help in the treatment. It is important to differentiate between SIADH and CSWS when trying to ascertain a case for patients with acute brain injury, as the treatment of the two are diametrically opposite.

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