scholarly journals Systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysis

2018 ◽  
Author(s):  
Xiang Yang ◽  
Seidu A. Richard ◽  
Jiagang Liu ◽  
Siqing Huang
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Subarachnoid Hemorrhage ◽  
Lupus Erythematosus ◽  
Neurological Complications ◽  
Cord Compression ◽  
Normal Function ◽  
Lower Limbs ◽  
Systemic Lupus ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal

Subarachnoid hemorrhage (SAH) is an uncommon complication of systemic lupus erythematosus (SLE). Solitary association of fatal spinal SAH as a complication of SLE, has not been encountered much in literature although coexisting acute cerebral and spinal SAH have been associated with SLE. We present a 39-year old female with initial diagnosis of SLE eight years ago who suddenly developed a productive cough, acute abdomen and paralysis of the lower limbs. Magnetic resonance imaging of the spine revealed thoracic spinal SAH with varying degrees of thoracic spinal cord compression. The hemorrhage was total evacuated via surgery. She regained normal function of her lower limbers after the operation with no further neurological complications. One of the rare but fatal complications of SLE is solitary spinal SAH without cranial involvement. The best and most appropriate management of this kind of presentation is surgical decompression of the hematoma with total hemostasis. The cause of hemorrhage should be identified intra-operatively and treated appropriately.

scholarly journals Longitudinal extensive transverse myelitis: a rare neurological complication of systemic lupus erythematosus

2019 ◽  
Vol 12 (4) ◽  
pp. e228950
Author(s):  
Sara Seyedali ◽  
Deborah R Alpert
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Neurological Complication ◽  
Transverse Myelitis ◽  
Systemic Lupus ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Longitudinal Extensive Transverse Myelitis ◽  
Intravenous Steroids ◽  
Extensive Transverse Myelitis

We present a 47-year-old woman with recently diagnosed systemic lupus erythematosus who developed progressive numbness and tingling of her upper and lower extremities, followed by weakness and difficulty ambulating. She was diagnosed with longitudinal extensive transverse myelitis involving her entire cervical and thoracic spinal cord. Infectious workup was unrevealing. She failed to respond to pulse–dose intravenous steroids, but slowly improved with the addition of plasmapheresis and cyclophosphamide. Following maintenance treatment with mycophenolate mofetil and slow tapering of oral steroids, she has maintained complete remission with significant recovery of neurological function.

scholarly journals A report of chronic intestinal pseudo-obstruction related to systemic lupus erythematosus

Open Medicine ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. 562-564 ◽  
Author(s):  
Ruiqiang Wang ◽  
Bowen Zheng ◽  
Biyue Wang ◽  
Pupu Ma ◽  
Fengmei Chen ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Clinical Symptoms ◽  
Gastrointestinal Disorder ◽  
Lower Limbs ◽  
Class Iii ◽  
Systemic Lupus ◽  
Intravenous Corticosteroid ◽  
Clinical Presentations ◽  
Intestinal Pseudo Obstruction

AbstractChronic intestinal pseudo-obstruction (CIPO) is a functional gastrointestinal disorder with symptoms of ileus. CIPO can either be idiopathic or secondary to other diseases such as systemic lupus erythematosus (SLE). SLE is involved in many parts of the gastrointestinal system with variable clinical presentations. Reports about reduplicated CIPO as a complication of SLE is infrequent. A 49-year-old female suffering from clinical symptoms of ileus has been hospitalized 3 times over 1 year. Her examination results showed no observation of mechanical obstruction. In August 2017, she came to the nephrology department due to edema in both lower limbs along with symptoms of ileus. After thorough examination, she was diagnosed with secondary CIPO related to SLE. Results of renal biopsy confirmed to be lupus nephritis (Class III-(A) + V). The symptoms of ileus are gradually improved after treatment of full-dose intravenous corticosteroid for 5 days.

scholarly journals Systemic lupus erythematosus with pitting oedema of the distal lower limbs

Rheumatology ◽  
1998 ◽  
Vol 37 (1) ◽  
pp. 104-105 ◽  
Author(s):  
E. Pittau ◽  
A. Tinti ◽  
L. Martini ◽  
A. Bogliolo ◽  
G. Perpignano
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Lower Limbs ◽  
Systemic Lupus

Subarachnoid hemorrhage in systemic lupus erythematosus: Systematic review and report of three cases

2015 ◽  
Vol 128 ◽  
pp. 17-24 ◽  
Author(s):  
Ramon Torné ◽  
Ana Rodríguez-Hernández ◽  
Teuddis Bernard ◽  
Fuat Arikan Abelló ◽  
Jordi Vilalta Castan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Systemic Lupus Erythematosus ◽  
Subarachnoid Hemorrhage ◽  
Lupus Erythematosus ◽  
Systemic Lupus

scholarly journals A rare form of anemia in systemic lupus erythematosus

Reumatismo ◽  
2017 ◽  
Vol 69 (3) ◽  
pp. 119
Author(s):  
C.A. Mansoor ◽  
R. Narayan
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Pernicious Anemia ◽  
Lupus Erythematosus ◽  
Healthy Woman ◽  
Underlying Mechanism ◽  
Lower Limbs ◽  
Deficiency Anemia ◽  
Systemic Lupus ◽  
Rare Form ◽  
Rare Association

Mechanisms responsible for anemia in systemic lupus erythematosus (SLE) can be immune or non-immune. A 27-year-old previously healthy woman was admitted with echymotic patches over the lower limbs for six months, multiple joint pain and fatigue for 2 months. She had severe pallor and multiple echymotic patches over the lower limbs. She was diagnosed with SLE with pernicious anemia and iron deficiency anemia. The rare association of SLE with pernicious anemia was reported previously in few patients. Treatment of SLE along with B12 supplementation is necessary for such patients. Since etiology for anemia in SLE can be of various kinds, a detailed workup for identifying the underlying mechanism is necessary.

Subarachnoid hemorrhage and systemic lupus erythematosus

Lupus ◽  
2000 ◽  
Vol 9 (7) ◽  
pp. 521-526 ◽  
Author(s):  
A Mimori ◽  
T Suzuki ◽  
M Hashimoto ◽  
H Nara ◽  
T Yoshio ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Subarachnoid Hemorrhage ◽  
Lupus Erythematosus ◽  
Systemic Lupus
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