Povidone-iodine toxicity in a child posted for laparoscopic removal of hepatic and renal hydatid cysts

Hydatid disease is a zoonotic infection caused by larval stages of dog tapeworms belonging to the genus Echinococcus (family taeniidae) and is also referred to as echinococcosis. Human cystic echinococcosis caused byE. granulosusis the most common presentation and probably accounts for more than 95% of the estimated 2-3 million annual worldwide cases. The liver (70–80%) and lungs (15–25%) are the most frequent locations for echinococcal cysts. The diagnosis is made through the combined assessment of clinical, radiological, and laboratory findings. The treatment is mainly surgical, and, with appropriate diagnosis and treatment, prognosis is good. With advances and increasing experience in laparoscopic surgery, many more attempts have been made to offer the advantage of such a procedure to these patients (Chowbey et al. (2003)).

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POVIDONE-IODINE TOXICITY

The Lancet ◽

10.1016/s0140-6736(76)92390-4 ◽

1976 ◽

Vol 308 (7978) ◽

pp. 207 ◽

Cited By ~ 6

Author(s):

JonathanL. Meakins ◽

JohnB. Pietsch

Keyword(s):

Povidone Iodine ◽

Iodine Toxicity

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Iodine toxicity secondary to continuous povidone-iodine mediastinal irrigation in dogs

Journal of Surgical Research ◽

10.1016/0022-4804(90)90191-4 ◽

1990 ◽

Vol 49 (5) ◽

pp. 428-434 ◽

Cited By ~ 11

Author(s):

Philip L. Glick ◽

B.Joseph Guglielmo ◽

Michael E. Winter ◽

Walter Finkbeiner ◽

Kevin Turley

Keyword(s):

Povidone Iodine ◽

Mediastinal Irrigation ◽

Iodine Toxicity

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A case of ARF after chromopertubation with povidone iodine

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20182923 ◽

2018 ◽

Vol 7 (7) ◽

pp. 2982 ◽

Cited By ~ 1

Author(s):

Savita S. Gautam ◽

Rajesh S. Gautam

Keyword(s):

Renal Failure ◽

Acute Renal Failure ◽

Povidone Iodine ◽

Symptomatic Treatment ◽

Favourable Outcome ◽

Clinical Feature ◽

Cutaneous Lesions ◽

Tubular Necrosis ◽

Cutaneous Administration ◽

Iodine Toxicity

Povidone iodine is a widely-used antiseptic agent, especially for cutaneous lesions. Despite its apparent innocuousness, some cases of acute renal failure are reportedly due to iodine toxicity. Authors report a case of an acute renal failure secondary to povidone iodine exposure in a 22-year-old woman. She underwent a hysteroscopy for diagnosis of secondary sterility with bilateral tubal block in hysterosalpingogram, and povidone iodine was used as the contrast agent. She developed acute renal failure with oliguria, later on anuria during the postoperative period. Treatment with diuretics and hemodialysis led to a favourable outcome and return of normal kidney function. Mucosal administration of povidone iodine appears to lead to greater iodine toxicity than cutaneous administration. The clinical feature of this patient suggested tubular necrosis caused by iodine, after the other possible causes of acute renal failure were ruled out. Acute renal failure secondary to povidone iodine administration is possible, especially through mucosal surfaces. Outcome is favourable after the conclusion of exposure and symptomatic treatment.

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